Search Results - "Luippold, Gerd"

Short- and Longterm Glycemic Control of Streptozotocin-Induced Diabetic Rats Using Different Insulin Preparations by Luippold, Gerd, Bedenik, Jessica, Voigt, Anke, Grempler, Rolf

“…The chemical induction of diabetes with STZ has gained popularity because of the relative ease of rendering normal animals diabetic. Insulin substitution is…”
Get full text

Characterization of Micro-RNA Changes during the Progression of Type 2 Diabetes in Zucker Diabetic Fatty Rats by Delic, Denis, Eisele, Claudia, Schmid, Ramona, Luippold, Gerd, Mayoux, Eric, Grempler, Rolf

“…The aim of the present pilot study was the identification of micro-RNA changes over time during the development and progression of type 2 diabetes (T2D) in…”
Get full text

An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo by Schiele, Felix, Park, John, Redemann, Norbert, Luippold, Gerd, Nar, Herbert

“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with autosomal dominant hypercholesterolemia, a state of elevated levels of LDL…”
Get full text

Effects of a single dose of amisulpride on functional brain changes during reward- and motivation-related processing using task-based fMRI in healthy subjects and patients with major depressive disorder — study protocol for a randomized clinical trial by Carstens, Luisa, Popp, Margot, Keicher, Christian, Hertrampf, Rita, Weigner, David, Meiering, Marvin S, Luippold, Gerd, Süssmuth, Sigurd D, Beckmann, Christian F, Wunder, Andreas, Grimm, Simone

“…Abstract Background Anhedonia and other deficits in reward- and motivation-related processing in psychiatric patients, including patients with major depressive…”
Get full text

Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK) by Grempler, Rolf, Wolff, Michael, Simon, Eric, Schmid, Ramona, Eisele, Claudia, Rieber, Kathrin, Fischer, Elke, Mettel, Sonja, Gabrielyan, Ogsen, Delic, Denis, Luippold, Gerd, Redeman, Norbert

“…Activation of the AMP-activated protein kinase (AMPK) is an attractive approach for the treatment of type 2 diabetes. AMPK activation reduces glucose levels in…”
Get full text

Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors by Uhrig-Schmidt, Silke, Geiger, Matthias, Luippold, Gerd, Birk, Gerald, Mennerich, Detlev, Neubauer, Heike, Grimm, Dirk, Wolfrum, Christian, Kreuz, Sebastian

“…In recent years, the increasing prevalence of obesity and obesity-related co-morbidities fostered intensive research in the field of adipose tissue biology. To…”
Get full text

Arterial blood pressure and renal sodium excretion in dopamine D3 receptor knockout mice by Staudacher, Torsten, Pech, Bärbel, Tappe, Michael, Gross, Gerhard, Mühlbauer, Bernd, Luippold, Gerd

“…Alterations in the dopaminergic system may contribute to the development of hypertension. Recently, it has been reported that pentobarbital-anesthetized mice…”
Get full text

Simultaneous determination of adenosine, S-adenosylhomocysteine and S-adenosylmethionine in biological samples using solid-phase extraction and high-performance liquid chromatography by Luippold, Gerd, Delabar, Ursula, Kloor, Doris, Mühlbauer, Bernd

“…A sensitive and rapid method for measuring simultaneously adenosine, S-adenosylhomocysteine and S-adenosylmethionine in renal tissue, and for the analysis of…”
Get full text

Subapical Localization of the Dopamine D3 Receptor in Proximal Tubules of the Rat Kidney by Nurnberger, Asja, Rabiger, Marcus, Mack, Andreas, Diaz, Jorge, Sokoloff, Pierre, Muhlbauer, Bernd, Luippold, Gerd

“…The dopamine D3 receptor (D3R), intensively studied in neuroscience, also plays an important role in the regulation of renal and cardiovascular function. In…”
Get full text

Dopamine D3 Receptor mRNA and Renal Response to D3 Receptor Activation in Spontaneously Hypertensive Rats by LUIPPOLD, Gerd, PIESCH, Christine, OSSWALD, Hartmut, MÜHLBAUER, Bernd

“…Defective dopamine receptors may be involved in the development of hypertension. Recently, it has been shown that gene expression and function of the renal…”
Get full text

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling by Zhang, Qian, Delessa, Challa Tenagne, Augustin, Robert, Bakhti, Mostafa, Colldén, Gustav, Drucker, Daniel J., Feuchtinger, Annette, Caceres, Cristina Garcia, Grandl, Gerald, Harger, Alexandra, Herzig, Stephan, Hofmann, Susanna, Holleman, Cassie Lynn, Jastroch, Martin, Keipert, Susanne, Kleinert, Maximilian, Knerr, Patrick J., Kulaj, Konxhe, Legutko, Beata, Lickert, Heiko, Liu, Xue, Luippold, Gerd, Lutter, Dominik, Malogajski, Emilija, Medina, Marta Tarquis, Mowery, Stephanie A., Blutke, Andreas, Perez-Tilve, Diego, Salinno, Ciro, Sehrer, Laura, DiMarchi, Richard D., Tschöp, Matthias H., Stemmer, Kerstin, Finan, Brian, Wolfrum, Christian, Müller, Timo D.

“…Uncertainty exists as to whether the glucose-dependent insulinotropic polypeptide receptor (GIPR) should be activated or inhibited for the treatment of…”
Get full text

Differences in kidney-specific DPP-4 inhibition by linagliptin and sitagliptin by Luippold, Gerd, Mark, Michael, Klein, Thomas, Amann, Kerstin, Daniel, Christoph

“…The two dipeptidyl peptidase (DPP)-4 inhibitors, linagliptin and sitagliptin, were shown to exert different binding kinetics in vitro. Twenty-four hours after…”
Get full text

Dopamine D2 receptors mediate glomerular hyperfiltration due to amino acids by Luippold, G, Mühlbauer, B

“…Renal dopamine has been proposed to be involved in the regulation of glomerular filtration rate (GFR). Because inhibition of dopamine D2 receptors abolishes…”
Get more information

A high-throughput, image-based screen to identify kinases involved in brown adipocyte development by Perdikari, Aliki, Kulenkampff, Elisabeth, Rudigier, Carla, Neubauer, Heike, Luippold, Gerd, Redemann, Norbert, Wolfrum, Christian

“…Brown adipose tissue (BAT) is responsible for thermogenesis that is not associated with shivering through the process of converting chemical energy into heat…”
Get more information

2309-PUB: The Effect of Linagliptin on the Microbiome of Diabetic ZDF Rats by SAYOLS, SERGI, SIMON, ERIC, KLEIN, HOLGER, LEPARC, GERMAN G., MARK, MICHAEL, LUIPPOLD, GERD, KLEIN, THOMAS

“…Recent data suggest that the individual microbiome influences the pathology of type 2 diabetes (T2D). Linagliptin is a dipeptidyl peptidase 4 (DPP-4) inhibitor…”
Get full text

Potent Cholesteryl Ester Transfer Protein Inhibitors of Reduced Lipophilicity: 1,1′-Spiro-Substituted Hexahydrofuroquinoline Derivatives by Trieselmann, Thomas, Wagner, Holger, Fuchs, Klaus, Hamprecht, Dieter, Berta, Daniela, Cremonesi, Paolo, Streicher, Rüdiger, Luippold, Gerd, Volz, Astrid, Markert, Michael, Nar, Herbert

“…A series of 1,1′-spiro-substituted hexahydrofuroquinoline derivatives exhibiting potent cholesteryl ester transfer protein (CETP) inhibition at reduced…”
Get full text

Chronic renal denervation prevents glomerular hyperfiltration in diabetic rats by Luippold, Gerd, Beilharz, Martina, Mühlbauer, Bernd

“…Background. The increase in glomerular filtration rate (GFR) induced by amino acid infusion is attenuated in rats with chronic renal denervation. The aim of…”
Get full text

Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing by Suhre, Karsten, Römisch-Margl, Werner, de Angelis, Martin Hrabé, Adamski, Jerzy, Luippold, Gerd, Augustin, Robert

“…The fatty acid binding protein 4 (FABP4) belongs to the family of lipid chaperones that control intracellular fluxes and compartmentalization of their…”
Get more information

Norepinephrine and cerebral blood flow regulation in patients with arteriovenous malformations by Stüer, Carsten, Ikeda, Toshiki, Stoffel, Michael, Luippold, Gerd, Sakowitz, Oliver, Schaller, Karl, Meyer, Bernhard

“…To test the hypothesis that the sympathetic nervous system plays a role in cerebral blood flow regulation in patients with arteriovenous malformations (AVM)…”
Get full text

Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine by Kloor, Doris, Delabar, Ursula, Mühlbauer, Bernd, Luippold, Gerd, Osswald, Hartmut

“…Most S-adenosylmethionine (AdoMet)-dependent methyltransferases are regulated in vivo by the AdoMet/ S-adenosylhomocysteine (AdoHcy) ratio, also termed as…”
Get full text