Search Results - "Lui, Ki"
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CHCM1/CHCHD6, Novel Mitochondrial Protein Linked to Regulation of Mitofilin and Mitochondrial Cristae Morphology
Published in The Journal of biological chemistry (02-03-2012)“…The structural integrity of mitochondrial cristae is crucial for mitochondrial functions; however, the molecular events controlling the structural integrity…”
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HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism
Published in Radiation research (01-06-2015)“…Hypoxia is a major cause of radiation resistance, which may predispose to local recurrence after radiation therapy. While hypoxia increases tumor cell survival…”
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White Button Mushroom (Agaricus Bisporus) Exhibits Antiproliferative and Proapoptotic Properties and Inhibits Prostate Tumor Growth in Athymic Mice
Published in Nutrition and cancer (01-01-2008)“…White button mushrooms are a widely consumed food containing phytochemicals beneficial to cancer prevention. The purpose of this research was to evaluate the…”
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Identification and Characterization of RBEL1 Subfamily of GTPases in the Ras Superfamily Involved in Cell Growth Regulation
Published in The Journal of biological chemistry (03-07-2009)“…Recently, we reported the identification of a novel gene named RBEL1 (Rab-like protein 1) and characterized its two encoded isoforms, RBEL1A and RBEL1B, that…”
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RanGTPase: A Key Regulator of Nucleocytoplasmic Trafficking
Published in Molecular and cellular pharmacology (Windsor Mill, Md.) (2009)“…RanGTPase belongs to the Ras superfamily of small GTPases. It possesses a distinctive acidic C-terminal DEDDDL motif and predominantly localizes to the…”
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Efficacy and Tolerability of Brivaracetam in Chinese Population: Focus on Switch From Levetiracetam
Published in American journal of therapeutics (01-11-2023)Get full text
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Characterization of the weak estrogen receptor α agonistic activity of exemestane
Published in Breast cancer research and treatment (01-08-2009)“…Third generation aromatase inhibitors (AI) have shown good clinical efficacy in comparison to the anti-estrogen tamoxifen. The steroidal AI, exemestane (EXE)…”
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The Impact of Genetic Mutations on the Efficacy of Immunotherapies in Lung Cancer
Published in International journal of molecular sciences (07-11-2024)“…Lung cancer is the leading cause of cancer-related mortality worldwide, primarily driven by genetic mutations. The most common genetic alterations implicated…”
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Abstract 4676: 11α-O-2-methylbutanoyl-12β-O-tigloyl-tenacigenin B (MT2) is a novel paclitaxel chemosensitizer to inhibit growth in Taxol non-resistant and Taxol resistant cancers
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract 11α-O-2-methylbutanoyl-12β-O-tigloyl-tenacigenin B (MT2) is a single molecule isolated from a traditional Chinese Medicinal herb Marsdenia tenacissima…”
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The oncogenic potential of Rab-like protein 1A (RBEL1A) GTPase: The first review of RBEL1A research with future research directions and challenges
Published in Journal of Cancer (01-01-2023)“…Research on Rab-like protein 1A (RBEL1A) in the past two decades highlighted the oncogenic properties of this gene. Despite the emerging evidence, its…”
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Negative regulation of p53 by Ras superfamily protein RBEL1A
Published in Journal of cell science (01-06-2013)“…We had previously reported that RBEL1A, a novel Ras-like GTPase, was overexpressed in multiple human malignancies and that its depletion suppressed cell…”
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Amphiphilic Core-Shell Nanocomposite Particles for Enhanced Magnetic Resonance Imaging
Published in Particle & particle systems characterization (01-10-2016)“…A scalable synthesis of magnetic core–shell nanocomposite particles, acting as a novel class of magnetic resonance (MR) contrast agents, has been developed…”
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Regulation of p53 oligomerization by Ras superfamily protein RBEL1A
Published in Genes & cancer (01-07-2015)“…Our previous studies showed that RBEL1A overexpressed in multiple human malignancies and its depletion by RNAi caused severe growth inhibition in tumor cells…”
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Potential tumor-suppressive role of monoglyceride lipase in human colorectal cancer
Published in Oncogene (10-01-2013)“…Human monoglyceride lipase (MGL) is a recently identified lipase and very little is known about its regulation and function in cellular regulatory processes,…”
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MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERα ligands and ERRα ligands
Published in Biochemical pharmacology (15-07-2008)“…We have previously generated a breast cancer cell line, MCF-7aro, which over-expresses aromatase and is also ER positive. Recently, this MCF-7aro cell line was…”
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molecular basis of the interaction between the proline-rich SH3-binding motif of PNRC and estrogen receptor alpha
Published in Nucleic acids research (01-11-2006)“…PNRC and PNRC2 are members of a new family of nuclear receptor coactivators. We systematically determined the molecular basis and the structure/function…”
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Abstract 3841: RBEL1A, a novel GTPase is an important regulator of cell growth and cell survival
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract We have recently reported the characterization of RBEL1 proteins, a novel subfamily of the Ras/Rab-like GTPases. Our studies demonstrate that RBEL1…”
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Characterization of the weak estrogen receptor [alpha] agonistic activity of exemestane
Published in Breast cancer research and treatment (01-08-2009)“…Third generation aromatase inhibitors (AI) have shown good clinical efficacy in comparison to the anti-estrogen tamoxifen. The steroidal AI, exemestane (EXE)…”
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19
Brivaracetam use in Hong Kong: a post-marketing cohort study (P1-1.Virtual)
Published in Neurology (03-05-2022)“…Abstract only…”
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Prognostic factors of status epilepticus in adults: a 6- year retrospective study (P5.079)
Published in Neurology (06-04-2015)“…Abstract only…”
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