Search Results - "Lui, J W"

Compact frequency notched ultra-wideband fractal printed slot antenna by Lui, W.J., Cheng, C.H., Zhu, H.B.

“…A novel frequency notched ultra-wideband (UWB) fractal printed slot antenna is proposed. The antenna is similar in configuration to a conventional…”
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Frailty, pain and psychological variables among older adults living in Hong Kong nursing homes: can we do better to address multimorbidities? by Tse, M. M. Y., Lai, C., Lui, J. Y. W., Kwong, E., Yeung, S. Y.

“…Accessible summary What is known on the subject? Frailty and multimorbidity are common in later life. A higher level of frailty is associated with a higher…”
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PAX3 and ETS1 synergistically activate MET expression in melanoma cells by Kubic, J D, Little, E C, Lui, J W, Iizuka, T, Lang, D

“…Melanoma is a highly aggressive disease that is difficult to treat owing to rapid tumor growth, apoptotic resistance and high metastatic potential. The MET…”
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The Anti-HER3 mAb Seribantumab Effectively Inhibits Growth of Patient-Derived and Isogenic Cell Line and Xenograft Models with Oncogenic NRG1 Fusions by Odintsov, Igor, Lui, Allan J W, Sisso, Whitney J, Gladstone, Eric, Liu, Zebing, Delasos, Lukas, Kurth, Renate I, Sisso, Exequiel M, Vojnic, Morana, Khodos, Inna, Mattar, Marissa S, de Stanchina, Elisa, Leland, Shawn M, Ladanyi, Marc, Somwar, Romel

“…Oncogenic fusions involving the ( ) gene are found in approximately 0.2% of cancers of diverse histologies. The resulting chimeric NRG1 proteins bind…”
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Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements by Schram, Alison M, Odintsov, Igor, Espinosa-Cotton, Madelyn, Khodos, Inna, Sisso, Whitney J, Mattar, Marissa S, Lui, Allan J W, Vojnic, Morana, Shameem, Sara H, Chauhan, Thrusha, Torrisi, Jean, Ford, Jim, O'Connor, Marie N, Geuijen, Cecile A W, Schackmann, Ron C J, Lammerts van Bueren, Jeroen J, Wasserman, Ernesto, de Stanchina, Elisa, O'Reilly, Eileen M, Ladanyi, Marc, Drilon, Alexander, Somwar, Romel

“…NRG1 rearrangements are recurrent oncogenic drivers in solid tumors. NRG1 binds to HER3, leading to heterodimerization with other HER/ERBB kinases, increased…”
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MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by ROS1 Fusions by Sato, Hiroki, Schoenfeld, Adam J, Siau, Evan, Lu, Yue Christine, Tai, Huichun, Suzawa, Ken, Kubota, Daisuke, Lui, Allan J W, Qeriqi, Besnik, Mattar, Marissa, Offin, Michael, Sakaguchi, Masakiyo, Toyooka, Shinichi, Drilon, Alexander, Rosen, Neal X, Kris, Mark G, Solit, David, De Stanchina, Elisa, Davare, Monika A, Riely, Gregory J, Ladanyi, Marc, Somwar, Romel

“…ROS1 tyrosine kinase inhibitors (TKI) provide significant benefit in lung adenocarcinoma patients with ROS1 fusions. However, as observed with all targeted…”
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HER2 Antibody-Drug Conjugates Are Active against Desmoplastic Small Round Cell Tumor by Zhang, Tom, Febres-Aldana, Christopher A, Liu, Zebing, Dix, Jenna-Marie, Cheng, Ryan, Dematteo, Raymond G, Lui, Allan J W, Khodos, Inna, Gili, Leo, Mattar, Marissa S, Lisanti, Jeanine, Kwong, Charlene, Linkov, Irina, Tipping, Murray J, de Stanchina, Elisa, Odintsov, Igor, Ladanyi, Marc, Somwar, Romel

“…Desmoplastic small round cell tumor (DSRCT) is a rare but highly aggressive soft tissue sarcoma that arises in the abdominopelvic cavity of young males. Since…”
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Ultra-wideband folded loop antenna fed by coplanar waveguide by Lui, W. J.

“…In this article, a novel and successful design of ultra‐wideband folded loop antenna is proposed and investigated. The antenna is fed by coplanar waveguide…”
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Novel Preclinical Patient-Derived Lung Cancer Models Reveal Inhibition of HER3 and MTOR Signaling as Therapeutic Strategies for NRG1 Fusion-Positive Cancers by Odintsov, Igor, Mattar, Marissa S, Lui, Allan J W, Offin, Michael, Kurzatkowski, Christopher, Delasos, Lukas, Khodos, Inna, Asher, Marina, Daly, Robert M, Rekhtman, Natasha, de Stanchina, Elisa, Ganji, Gopinath, Ladanyi, Marc, Somwar, Romel

“…NRG1 rearrangements produce chimeric ligands that subvert the ERBB pathway to drive tumorigenesis. A better understanding of the signaling networks that…”
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CIC-Mediated Modulation of MAPK Signaling Opposes Receptor Tyrosine Kinase Inhibitor Response in Kinase-Addicted Sarcoma by Odintsov, Igor, Ortiz, Michael V, Khodos, Inna, Mattar, Marissa S, Lui, Allan J W, Kohsaka, Shinji, de Stanchina, Elisa, Bender, Julia L Glade, Ladanyi, Marc, Somwar, Romel

“…Kinase fusions have been identified in a growing subset of sarcomas, but a lack of preclinical models has impeded their functional analysis as therapeutic…”
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Combination of MDM2 and Targeted Kinase Inhibitors Results in Prolonged Tumor Control in Lung Adenocarcinomas With Oncogenic Tyrosine Kinase Drivers and MDM2 Amplification by Elkrief, Arielle, Odintsov, Igor, Smith, Roger S, Vojnic, Morana, Hayashi, Takuo, Khodos, Inna, Markov, Vladimir, Liu, Zebing, Lui, Allan J W, Bloom, Jamie L, Offin, Michael D, Rudin, Charles M, de Stanchina, Elisa, Riely, Gregory J, Somwar, Romel, Ladanyi, Marc

“…MDM2, a negative regulator of the TP53 tumor suppressor, is oncogenic when amplified. amplification (MDM2amp) is mutually exclusive with mutation and is seen…”
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Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations by Miyazaki, Isao, Odintsov, Igor, Ishida, Keiji, Lui, Allan J W, Kato, Masanori, Suzuki, Tatsuya, Zhang, Tom, Wakayama, Kentaro, Kurth, Renate I, Cheng, Ryan, Fujita, Hidenori, Delasos, Lukas, Vojnic, Morana, Khodos, Inna, Yamada, Yukari, Ishizawa, Kota, Mattar, Marissa S, Funabashi, Kaoru, Chang, Qing, Ohkubo, Shuichi, Yano, Wakako, Terada, Ryuichiro, Giuliano, Claudio, Lu, Yue Christine, Bonifacio, Annalisa, Kunte, Siddharth, Davare, Monika A, Cheng, Emily H, de Stanchina, Elisa, Lovati, Emanuela, Iwasawa, Yoshikazu, Ladanyi, Marc, Somwar, Romel

“…RET receptor tyrosine kinase is activated in various cancers (lung, thyroid, colon and pancreatic, among others) through oncogenic fusions or gain-of-function…”
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Author Correction: Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations by Miyazaki, Isao, Odintsov, Igor, Ishida, Keiji, Lui, Allan J. W., Kato, Masanori, Suzuki, Tatsuya, Zhang, Tom, Wakayama, Kentaro, Kurth, Renate I., Cheng, Ryan, Fujita, Hidenori, Delasos, Lukas, Vojnic, Morana, Khodos, Inna, Yamada, Yukari, Ishizawa, Kota, Mattar, Marissa S., Funabashi, Kaoru, Chang, Qing, Ohkubo, Shuichi, Yano, Wakako, Terada, Ryuichiro, Giuliano, Claudio, Lu, Yue Christine, Bonifacio, Annalisa, Kunte, Siddharth, Davare, Monika A., Cheng, Emily H., de Stanchina, Elisa, Lovati, Emanuela, Iwasawa, Yoshikazu, Ladanyi, Marc, Somwar, Romel

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A novel broadband multislot antenna fed by microstrip line by Lui, W. J., Cheng, C. H., Cheng, Y., Zhu, H. B.

“…A novel broadband multislot antenna fed by microstrip line is presented. By employing the multislot configuration, multimode resonances with close frequencies…”
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A compact ultra-wideband CPW-fed slot antenna with a forklike stub by Lui, W. J., Cheng, C. H., Cheng, Y., Zhu, H. B.

“…A novel ultra‐wideband compact slot antenna fed by a grounded coplanar waveguide (CPW) is presented. This antenna is similar to the conventional CPW‐fed slot…”
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Novel multilayer microstrip bandpass filter with multislots on ground plane by Lui, W. J., Deng, Z., Cheng, C. H., Zhu, H. B.

“…A novel multilayer microstrip bandpass filter is proposed in this paper. The filter is constructed on two substrates with multislots on the common ground plane…”
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MODL-01. TRACTABLE PATIENT-DERIVED MODELS FOR PRECLINICAL THERAPEUTIC STUDIES OF CNS METASTASES by Vojnic, Morana, Odintsov, Igor, Offin, Michael D, Lui, Allan J W, Khodos, Inna, Chang, Qing, Mattar, Marissa S, De Stanchina, Elisa, Ladanyi, Marc, Somwar, Romel

“…Abstract INTRODUCTION Brain metastases are the most common brain tumors and occur in 10-30% of cancer patients, whereas leptomeningeal disease (LMD) occurs in…”
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The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions by Odintsov, Igor, Lui, Allan J W, Sisso, Whitney J, Gladstone, Eric, Liu, Zebing, Delasos, Lukas, Kurth, Renate I, Sisso, Exequiel M, Vojnic, Morana, Khodos, Inna, Mattar, Marissa S, de Stanchina, Elisa, Leland, Shawn M, Ladanyi, Marc, Somwar, Romel

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Compact balanced antipodal slot antenna for ultra-wideband applications by Lui, W. J., Cheng, C. H., Zhu, H. B.

“…A novel, miniature balanced antipodal printed slot antenna for ultra‐wideband applications is proposed. The antenna is fed by strip‐line with a fork‐like stub…”
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