Search Results - "Luhua, Song"

4-Coumarate 3-hydroxylase in the lignin biosynthesis pathway is a cytosolic ascorbate peroxidase by Barros, Jaime, Escamilla-Trevino, Luis, Song, Luhua, Rao, Xiaolan, Serrani-Yarce, Juan Carlos, Palacios, Maite Docampo, Engle, Nancy, Choudhury, Feroza K., Tschaplinski, Timothy J., Venables, Barney J., Mittler, Ron, Dixon, Richard A.

“…Lignin biosynthesis is evolutionarily conserved among higher plants and features a critical 3-hydroxylation reaction involving phenolic esters. However,…”
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Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells by Lipper, Colin H., Karmi, Ola, Sohn, Yang Sung, Darash-Yahana, Merav, Lammert, Heiko, Song, Luhua, Liu, Amy, Mittler, Ron, Nechushtai, Rachel, Onuchic, José N., Jennings, Patricia A.

“…The NEET family is a relatively new class of three related [2Fe-2S] proteins (CISD1–3), important in human health and disease. While there has been growing…”
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Enhanced Tolerance to Oxidative Stress in Transgenic Arabidopsis Plants Expressing Proteins of Unknown Function by Luhua, Song, Ciftci-Yilmaz, Sultan, Harper, Jeffery, Cushman, John, Mittler, Ron

“…Over one-quarter of all plant genes encode proteins of unknown function that can be further classified as proteins with obscure features (POFs), which lack…”
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NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth by Sohn, Yang-Sung, Tamir, Sagi, Song, Luhua, Michaeli, Dorit, Matouk, Imad, Conlan, Andrea R., Harir, Yael, Holt, Sarah H., Shulaev, Vladimir, Paddock, Mark L., Hochberg, Abraham, Cabanchick, Ioav Z., Onuchic, José N., Jennings, Patricia A., Nechushtai, Rachel, Mittler, Ron

“…Mitochondria are emerging as important players in the transformation process of cells, maintaining the biosynthetic and energetic capacities of cancer cells…”
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Ultra‐fast alterations in mRNA levels uncover multiple players in light stress acclimation in plants by Suzuki, Nobuhiro, Devireddy, Amith R, Inupakutika, Madhuri A, Baxter, Aaron, Miller, Gad, Song, Luhua, Shulaev, Elena, Azad, Rajeev K, Shulaev, Vladimir, Mittler, Ron

“…The acclimation of plants to changes in light intensity requires rapid responses at several different levels. These include biochemical and biophysical…”
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Thiamin Confers Enhanced Tolerance to Oxidative Stress in Arabidopsis by Tunc-Ozdemir, Meral, Miller, Gad, Song, Luhua, Kim, James, Sodek, Ahmet, Koussevitzky, Shai, Misra, Amarendra Narayan, Mittler, Ron, Shintani, David

“…Thiamin and thiamin pyrophosphate (TPP) are well known for their important roles in human nutrition and enzyme catalysis. In this work, we present new evidence…”
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The mitochondrial localized CISD-3.1/CISD-3.2 proteins are required to maintain normal germline structure and function in Caenorhabditis elegans by King, Skylar D, Gray, Chipo F, Song, Luhua, Mittler, Ron, Padilla, Pamela A

“…Reproductive organs and developing tissues have high energy demands that require metabolic functions primarily supported by mitochondria function. The highly…”
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Expression of a dominant‐negative AtNEET‐H89C protein disrupts iron–sulfur metabolism and iron homeostasis in Arabidopsis by Zandalinas, Sara I., Song, Luhua, Sengupta, Soham, McInturf, Samuel A., Grant, DeAna G., Marjault, Henri‐Baptiste, Castro‐Guerrero, Norma A., Burks, David, Azad, Rajeev K., Mendoza‐Cozatl, David G., Nechushtai, Rachel, Mittler, Ron

“…Summary Iron–sulfur (Fe–S) clusters play an essential role in plants as protein cofactors mediating diverse electron transfer reactions. Because they can react…”
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Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress by Mittler, Ron, Kim, YongSig, Song, Luhua, Coutu, Jesse, Coutu, Alicia, Ciftci-Yilmaz, Sultan, Lee, Hojoung, Stevenson, Becky, Zhu, Jian-Kang

“…C 2H 2-zinc finger proteins that contain the EAR repressor domain are thought to play a key role in modulating the defense response of plants to abiotic…”
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Targeted Enhancement of Glutamate-to-γ-Aminobutyrate Conversion in Arabidopsis Seeds Affects Carbon-Nitrogen Balance and Storage Reserves in a Development-Dependent Manner by Fait, Aaron, Nesi, Adriano Nunes, Angelovici, Ruthie, Lehmann, Martin, Pham, Phuong Anh, Song, Luhua, Haslam, Richard P., Napier, Johnathan A., Galili, Gad, Fernie, Alisdair R.

“…In seeds, glutamate decarboxylase (GAD) operates at the metabolic nexus between carbon and nitrogen metabolism by catalyzing the unidirectional decarboxylation…”
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Linking genes of unknown function with abiotic stress responses by high-throughput phenotype screening by Luhua, Song, Hegie, Alicia, Suzuki, Nobuhiro, Shulaev, Elena, Luo, Xiaozhong, Cenariu, Diana, Ma, Vincent, Kao, Stephanie, Lim, Jennie, Gunay, Meryem Betul, Oosumi, Teruko, Lee, Seung Cho, Harper, Jeffery, Cushman, John, Gollery, Martin, Girke, Thomas, Bailey-Serres, Julia, Stevenson, Rebecca A., Zhu, Jian-Kang, Mittler, Ron

“…Over 13% of all genes in the Arabidopsis thaliana genome encode for proteins classified as having a completely unknown function, with the function of >30% of…”
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Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer by Bai, Fang, Morcos, Faruck, Sohn, Yang-Sung, Darash-Yahana, Merav, Rezende, Celso O., Lipper, Colin H., Paddock, Mark L., Song, Luhua, Luo, Yuting, Holt, Sarah H., Tamir, Sagi, Theodorakis, Emmanuel A., Jennings, Patricia A., Onuchic, José N., Mittler, Ron, Nechushtai, Rachel

“…Identification of novel drug targets and chemotherapeutic agents is a high priority in the fight against cancer. Here, we report that MAD-28, a designed…”
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The cisd gene family regulates physiological germline apoptosis through ced-13 and the canonical cell death pathway in Caenorhabditis elegans by King, Skylar D., Gray, Chipo F., Song, Luhua, Nechushtai, Rachel, Gumienny, Tina L., Mittler, Ron, Padilla, Pamela A.

“…Programmed cell death, which occurs through a conserved core molecular pathway, is important for fundamental developmental and homeostatic processes. The human…”
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Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells by Holt, Sarah H, Darash-Yahana, Merav, Sohn, Yang Sung, Song, Luhua, Karmi, Ola, Tamir, Sagi, Michaeli, Dorit, Luo, Yuting, Paddock, Mark L, Jennings, Patricia A, Onuchic, José N, Azad, Rajeev K, Pikarsky, Eli, Cabantchik, Ioav Z, Nechushtai, Rachel, Mittler, Ron

“…Maintaining iron (Fe) ion and reactive oxygen species homeostasis is essential for cellular function, mitochondrial integrity and the regulation of cell death…”
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The EAR-motif of the Cys2/His2-type Zinc Finger Protein Zat7 Plays a Key Role in the Defense Response of Arabidopsis to Salinity Stress by Ciftci-Yilmaz, Sultan, Morsy, Mustafa R., Song, Luhua, Coutu, Alicia, Krizek, Beth A., Lewis, Michael W., Warren, Daniel, Cushman, John, Connolly, Erin L., Mittler, Ron

“…Cys2/His2-type zinc finger proteins, which contain the EAR transcriptional repressor domain, are thought to play a key role in regulating the defense response…”
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Characterization of Arabidopsis NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism by Nechushtai, Rachel, Conlan, Andrea R., Harir, Yael, Song, Luhua, Yogev, Ohad, Eisenberg-Domovich, Yael, Livnah, Oded, Michaeli, Dorit, Rosen, Rachel, Ma, Vincent, Luo, Yuting, Zuris, John A., Paddock, Mark L., Cabantchik, Zvi Ioav, Jennings, Patricia A., Mittler, Ron

“…The NEET family is a newly discovered group of proteins involved in a diverse array of biological processes, including autophagy, apoptosis, aging, diabetes,…”
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Interactions between mitoNEET and NAF-1 in cells by Karmi, Ola, Holt, Sarah H, Song, Luhua, Tamir, Sagi, Luo, Yuting, Bai, Fang, Adenwalla, Ammar, Darash-Yahana, Merav, Sohn, Yang-Sung, Jennings, Patricia A, Azad, Rajeev K, Onuchic, Jose' N, Morcos, Faruck, Nechushtai, Rachel, Mittler, Ron

“…The NEET proteins mitoNEET (mNT) and nutrient-deprivation autophagy factor-1 (NAF-1) are required for cancer cell proliferation and resistance to oxidative…”
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Lysine enhances methionine content by modulating the expression of S-adenosylmethionine synthase by Hacham, Yael, Song, Luhua, Schuster, Gadi, Amir, Rachel

“…Lysine and methionine are two essential amino acids whose levels affect the nutritional quality of cereals and legume plants. Both amino acids are synthesized…”
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The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells by Zandalinas, Sara I., Song, Luhua, Nechushtai, Rachel, Mendoza-Cozatl, David G., Mittler, Ron

“…NEET proteins are conserved 2Fe-2S proteins that regulate the levels of iron and reactive oxygen species in plant and mammalian cells. Previous studies of…”
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Cloning and characterization of Arabidopsis homologues of the animal CstF complex that regulates 3′ mRNA cleavage and polyadenylation by Yao, Youli, Song, Luhua, Katz, Yael, Galili, Gad

“…The 3′ cleavage and polyadenylation of mRNAs has been studied in detail in animals and yeast, but not in plants. Aimed at elucidating the regulation of mRNA 3′…”
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