Search Results - "Luff, Marie"

Racial/ethnic disparities in thyroid cancer in California, 1999–2017 by Luff, Marie K., Kim, Jiyoon, Tseng, Chi-Hong, Livhits, Masha J., Yeh, Michael W., Wu, James X.

“…Recent studies examining treatment disparities in thyroid cancer care found that appropriate use of surgery and radioactive iodine may be improving over time…”
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Postmarket Surveillance of Neuroendovascular Devices by Luff, Marie K., Sedrakyan, Art, Ansari, Sameer A., Siddiqui, Adnan H., Liebeskind, David S.

“…Endovascular devices have catalyzed a global industry for advanced technologies such as flow diverters and stent retrievers. Though adoption of these devices…”
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Modular polymer platform as a novel approach to head and neck cancer therapy by Alhiyari, Yazeed, Shao, Jundong, Han, Albert Y., Miller, Amanda, Krane, Jeffrey F., Luff, Marie, Momcilovic, Milica, Shackelford, David, Gu, Zhen, John, Maie A. St

“…Head and neck cancer is the sixth most common cancer in the world, with more than 300,000 deaths attributed to the disease annually. Aggressive surgical…”
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Nigella sativa oil mitigates xerostomia and preserves salivary function in radiotherapy‐treated mice by Luff, Marie, Evans, Lauran, Hiyari, Sarah, Kwan, Kera, Cameron, Brian, Miller, Amanda, St. John, Maie, Alhiyari, Yazeed

“…Objective This study aimed to assess if Nigella sativa oil (NSO), a health supplement containing thymoquinone as a major component, can act as a protective…”
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Genetic determinants of daytime napping and effects on cardiometabolic health by Dashti, Hassan S., Daghlas, Iyas, Lane, Jacqueline M., Huang, Yunru, Udler, Miriam S., Wang, Heming, Ollila, Hanna M., Jones, Samuel E., Kim, Jaegil, Wood, Andrew R., Weedon, Michael N., Aslibekyan, Stella, Garaulet, Marta, Saxena, Richa

“…Daytime napping is a common, heritable behavior, but its genetic basis and causal relationship with cardiometabolic health remain unclear. Here, we perform a…”
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Identifying Targets for Innovation in Amazon Reviews of Bedwetting Alarms: Thematic Analysis by Sahoo, Astha, Starr, Savannah Leah, Osadchiy, Vadim, Desai, Sophia, Iyer, Neha, Luff, Marie, Sollender, Grace E, Sturm, Renea

“…Nocturnal enuresis (NE) is a frequent diagnosis in pediatric and adolescent populations with an estimated prevalence of around 15% at the age of 6 years. NE…”
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders by Eijsbouts, Chris, Zheng, Tenghao, Kennedy, Nicholas A., Bonfiglio, Ferdinando, Anderson, Carl A., Moutsianas, Loukas, Holliday, Joanne, Shi, Jingchunzi, Shringarpure, Suyash, Voda, Alexandru-Ioan, Farrugia, Gianrico, Franke, Andre, Hübenthal, Matthias, Abecasis, Gonçalo, Zawistowski, Matthew, Skogholt, Anne Heidi, Ness-Jensen, Eivind, Hveem, Kristian, Esko, Tõnu, Teder-Laving, Maris, Zhernakova, Alexandra, Camilleri, Michael, Boeckxstaens, Guy, Whorwell, Peter J., Spiller, Robin, McVean, Gil, D’Amato, Mauro, Jostins, Luke, Parkes, Miles

“…Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying…”
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Genetic analyses identify widespread sex-differential participation bias by Pirastu, Nicola, Cordioli, Mattia, Nandakumar, Priyanka, Mignogna, Gianmarco, Abdellaoui, Abdel, Hollis, Benjamin, Kanai, Masahiro, Rajagopal, Veera M., Parolo, Pietro Della Briotta, Baya, Nikolas, Carey, Caitlin E., Karjalainen, Juha, Als, Thomas D., Van der Zee, Matthijs D., Day, Felix R., Ong, Ken K., Morisaki, Takayuki, de Geus, Eco, Bellocco, Rino, Okada, Yukinori, Børglum, Anders D., Joshi, Peter, Auton, Adam, Hinds, David, Neale, Benjamin M., Walters, Raymond K., Nivard, Michel G., Perry, John R. B., Ganna, Andrea

“…Genetic association results are often interpreted with the assumption that study participation does not affect downstream analyses. Understanding the genetic…”
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Abstract 1729: SUV420H1 depletion reveals therapeutic potential in HPV-negative head and neck squamous cell carcinoma by Moshiri, Arfa, Kim, Sohyoung, Luff, Marie, Saloura, Vassiliki

“…Abstract Human Papilloma Virus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) poses a significant clinical challenge with limited treatment…”
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Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis by Ong, Jue-Sheng, An, Jiyuan, Han, Xikun, Law, Matthew H, Nandakumar, Priyanka, Schumacher, Johannes, Gockel, Ines, Bohmer, Anne, Jankowski, Janusz, Palles, Claire, Olsen, Catherine M, Neale, Rachel E, Fitzgerald, Rebecca, Thrift, Aaron P, Vaughan, Thomas L, Buas, Matthew F, Hinds, David A, Gharahkhani, Puya, Kendall, Bradley J, MacGregor, Stuart

“…Gastro-oesophageal reflux disease (GERD) has heterogeneous aetiology primarily attributable to its symptom-based definitions. GERD genome-wide association…”
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Recruitment of a Virtual Nationwide Cohort of LRRK2 G2019S Carriers (4746) by Myers, Taylor, Schneider, Ruth, Jensen-Roberts, Stella, Rowbotham, Helen, Luff, Marie, Chanoff, Eli, Amodeo, Katherine, Sharma, Saloni, Alcalay, Roy, Cannon, Paul, Dorsey, E. Ray, Holloway, Robert

“…Abstract only…”
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Prevalence of Alpha-1 Antitrypsin Deficiency, Self-Reported Behavior Change, and Health Care Engagement Among Direct-to-Consumer Recipients of a Personalized Genetic Risk Report by Ashenhurst, James R., Nhan, Hoang, Shelton, Janie F., Wu, Shirley, Tung, Joyce Y., Elson, Sarah L., Stoller, James K., Agee, Michelle, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bryc, Katarzyna, Bullis, Emily, Cameron, Briana, Coker, Daniella, Partida, Gabriel Cuellar, Dhamija, Devika, Das, Sayantan, Elson, Sarah L., Filshtein, Teresa, Fletez-Brant, Kipper, Fontanillas, Pierre, Freyman, Will, Gandhi, Pooja M., Heilbron, Karl, Hicks, Barry, Hinds, David A., Huber, Karen E., Jewett, Ethan M., Jiang, Yunxuan, Kleinman, Aaron, Kukar, Katelyn, Lane, Vanessa A., Lin, Keng-Han, Lowe, Maya, Luff, Marie K., McCreight, Jennifer C., McIntyre, Matthew H., McManus, Kimberly F., Micheletti, Steven J., Moreno, Meghan E., Mountain, Joanna L., Mozaffari, Sahar V., Nandakumar, Priyanka, Noblin, Elizabeth S., O’Connell, Jared, Petrakovitz, Aaron A., Poznik, G. David, Schumacher, Morgan, Shastri, Anjali J., Shelton, Janie F., Shi, Jingchunzi, Shringarpure, Suyash, Tian, Chao, Tran, Vinh, Tung, Joyce Y., Wang, Xin, Wang, Wei, Weldon, Catherine H., Wilton, Peter

“…Alpha-1 antitrypsin deficiency (AATD) is an autosomal co-dominant condition that predisposes to emphysema, cirrhosis, panniculitis, and vasculitis…”
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Abstract 2636: Epigenetic landscape of CD8+ T cell exhaustion and tissue residency in HPV-negative head and neck squamous cell carcinoma by Luff, Marie K., Craviero, Marco, Dar, Mohd Saleem, McKinnon, Katherine, Kaskas, Amir, Allen, Clint T., Saloura, Vassiliki

“…Abstract Background Head and neck cancer is the 8th most common cancer worldwide. Human Papilloma Virus (HPV)-negative head and neck squamous cell carcinoma…”
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Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring by Campos, Adrian I, Ingold, Nathan, Huang, Yunru, Mitchell, Brittany L, Kho, Pik-Fang, Han, Xikun, García-Marín, Luis M, Ong, Jue-Sheng, Law, Matthew H, Yokoyama, Jennifer S, Martin, Nicholas G, Dong, Xianjun, Cuellar-Partida, Gabriel, MacGregor, Stuart, Aslibekyan, Stella, Rentería, Miguel E

“…Abstract Study Objectives Despite its association with severe health conditions, the etiology of sleep apnea (SA) remains understudied. This study sought to…”
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Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson’s disease by Smolensky, Luba, Amondikar, Ninad, Crawford, Karen, Neu, Scott, Kopil, Catherine M., Daeschler, Margaret, Riley, Lindsey, Brown, Ethan, Toga, Arthur W., Tanner, Caroline

“…Fox Insight is an online, longitudinal health study of people with and without Parkinson’s disease with targeted enrollment set to at least 125,000…”
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Genome-wide association analysis and replication in 810,625 individuals with varicose veins by Ahmed, Waheed-Ul-Rahman, Kleeman, Sam, Ng, Michael, Wang, Wei, Auton, Adam, Lee, Regent, Handa, Ashok, Zondervan, Krina T., Wiberg, Akira, Furniss, Dominic

“…Varicose veins affect one-third of Western society, with a significant subset of patients developing venous ulceration, costing $14.9 billion annually in the…”
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Clinical Needs Discovery in Pediatric Urology: Utilizing the Biodesign Process by Luff, Marie K., Zarrin, David A., Zhou, Li, Sahoo, Astha, Desai, Sophia, Iyer, Neha, Starr, Savannah L., Sturm, Renea M.

“…Introduction Biodesign innovation processes provide a needs-driven approach to medical innovation, empowering both medical trainees and health care providers…”
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A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease by Wightman, Douglas P, Jansen, Iris E, Savage, Jeanne E, Shadrin, Alexey A, Bahrami, Shahram, Holland, Dominic, Rongve, Arvid, Børte, Sigrid, Winsvold, Bendik S, Martinsen, Amy E, Skogholt, Anne Heidi, Willer, Cristen, Bråthen, Geir, Bosnes, Ingunn, Nielsen, Jonas Bille, Fritsche, Lars G, Thomas, Laurent F, Pedersen, Linda M, Gabrielsen, Maiken E, Meisingset, Tore Wergeland, Zhou, Wei, Proitsi, Petroula, Dobson, Richard, Velayudhan, Latha, Sealock, Julia M, Pedersen, Nancy L, Reynolds, Chandra A, Karlsson, Ida K, Magnusson, Sigurdur, Stefansson, Hreinn, Thordardottir, Steinunn, Jonsson, Palmi V, Snaedal, Jon, Zettergren, Anna, Kern, Silke, Waern, Margda, Zetterberg, Henrik, Blennow, Kaj, Stordal, Eystein, Zwart, John-Anker, Selnes, Per, Saltvedt, Ingvild, Sando, Sigrid B, Ulstein, Ingun, Djurovic, Srdjan, Fladby, Tormod, Aarsland, Dag, Ripke, Stephan, Stefansson, Kari, Posthuma, Danielle, Aslibekyan, Stella, Babalola, Elizabeth, Bielenberg, Jessica, Bullis, Emily, Cameron, Briana, Coker, Daniella, Partida, Gabriel Cuellar, Dhamija, Devika, Das, Sayantan, Elson, Sarah L, Filshtein, Teresa, Fletez-Brant, Kipper, Fontanillas, Pierre, Freyman, Will, Gandhi, Pooja M, Hicks, Barry, Hinds, David A, Huber, Karen E, Jewett, Ethan M, Jiang, Yunxuan, Kleinman, Aaron, Kukar, Katelyn, Lane, Vanessa, Lin, Keng-Han, Lowe, Maya, Luff, Marie K, McCreight, Jennifer C, McIntyre, Matthew H, McManus, Kimberly F, Micheletti, Steven J, Moreno, Meghan E, Mountain, Joanna L, Mozaffari, Sahar V, Nandakumar, Priyanka, Noblin, Elizabeth S, O'Connell, Jared, Petrakovitz, Aaron A, Poznik, G David, Schumacher, Morgan, Shastri, Anjali J, Shelton, Janie F, Shi, Jingchunzi, Shringarpure, Suyash, Tian, Chao, Tran, Vinh, Tung, Joyce Y, Wang, Xin, Wang, Wei, Weldon, Catherine H, Wilton, Peter

“…Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts for 50-70% of dementia cases. Currently, only a fraction of the…”
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Smyd3-mediated immuno-modulation in HPV-negative head and neck squamous cell carcinoma mouse models by Tsai, Daniel E., Lovanov, Alexei, Abdelmaksoud, Abdalla, Akhtar, Jawad, Dar, Mohd Saleem, Luff, Marie, McKinnon, Katherine, Kim, Sohyoung, Robbins, Yvette, Huynh, Angel, Murali, Madhavi, Bernard, Benjamin, Sinkoe, Andrew, Luo, Xiaolin, B, Karim, Allen, Clint T., Saloura, Vassiliki

“…SET and MYND-domain containing protein 3 (SMYD3) mediates epigenetic repression of type I IFN response genes in human papillomavirus (HPV)-negative HNSCC…”
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Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy by Krebs, Kristi, Bovijn, Jonas, Zheng, Neil, Lepamets, Maarja, Censin, Jenny C., Jürgenson, Tuuli, Särg, Dage, Abner, Erik, Laisk, Triin, Luo, Yang, Skotte, Line, Geller, Frank, Feenstra, Bjarke, Wang, Wei, Auton, Adam, Agee, Michelle, Aslibekyan, Stella, Bell, Robert K., Bryc, Katarzyna, Clark, Sarah K., Elson, Sarah L., Fletez-Brant, Kipper, Fontanillas, Pierre, Furlotte, Nicholas A., Gandhi, Pooja M., Heilbron, Karl, Hicks, Barry, Hinds, David A., Huber, Karen E., Jewett, Ethan M., Jiang, Yunxuan, Kleinman, Aaron, Lin, Keng-Han, Litterman, Nadia K., Luff, Marie K., McCreight, Jennifer C., McIntyre, Matthew H., McManus, Kimberly F., Mountain, Joanna L., Mozaffari, Sahar V., Nandakumar, Priyanka, Noblin, Elizabeth S., Northover, Carrie A.M., O’Connell, Jared, Petrakovitz, Aaron A., Pitts, Steven J., Poznik, G. David, Sathirapongsasuti, J. Fah, Shastri, Anjali J., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Tunney, Robert J., Vacic, Vladimir, Wang, Xin, Zare, Amir S., Raychaudhuri, Soumya, Esko, Tõnu, Metspalu, Andres, Laur, Sven, Roden, Dan M., Wei, Wei-Qi, Holmes, Michael V., Lindgren, Cecilia M., Phillips, Elizabeth J., Mägi, Reedik, Milani, Lili, Fadista, João

“…Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscoring a need for understanding their underlying mechanisms and…”
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