Search Results - "Luengo Gil, Ginés"

Tumor-infiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer by García-Martínez, Elena, Gil, Ginés Luengo, Benito, Asunción Chaves, González-Billalabeitia, Enrique, Conesa, María Angeles Vicente, García García, Teresa, García-Garre, Elisa, Vicente, Vicente, Ayala de la Peña, Francisco

“…Tumor microenvironment immunity is associated with breast cancer outcome. A high lymphocytic infiltration has been associated with response to neoadjuvant…”
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Qualitative and Quantitative Comparison of Plasma Exosomes from Neonates and Adults by Peñas-Martínez, Julia, Barrachina, María N, Cuenca-Zamora, Ernesto José, Luengo-Gil, Ginés, Bravo, Susana Belén, Caparrós-Pérez, Eva, Teruel-Montoya, Raúl, Eliseo-Blanco, José, Vicente, Vicente, García, Ángel, Martínez-Martínez, Irene, Ferrer-Marín, Francisca

“…Exosomes are extracellular vesicles that contain nucleic acids, lipids and metabolites, and play a critical role in health and disease as mediators of…”
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Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria by Teruel-Montoya, Raúl, Luengo-Gil, Ginés, Vallejo, Fernando, Yuste, José Enrique, Bohdan, Nataliya, García-Barberá, Nuria, Espín, Salvador, Martínez, Constantino, Espín, Juan Carlos, Vicente, Vicente, Martínez-Martínez, Irene

“…Paroxysmal Nocturnal Hemoglobinuria (PNH) is a clonal disease of blood cells caused by the lack of glycosyl phosphatidyl inositol anchored proteins bound to…”
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Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway by Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo

“…Rearrangement of the actin cytoskeleton is a prerequisite for carcinoma cells to develop cellular protrusions, which are required for migration, invasion, and…”
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N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function by Águila, Sonia, Noto, Rosina, Luengo-Gil, Ginés, Espín, Salvador, Bohdan, Nataliya, de la Morena-Barrio, María Eugenia, Peñas, Julia, Rodenas, Maria Carmen, Vicente, Vicente, Corral, Javier, Manno, Mauro, Martínez-Martínez, Irene

“…N-linked glycosylation is a crucial post-translational modification involved in protein folding, function, and clearance. N-linked glycosylation is also used…”
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Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus by Guirao-Abad, José P, Weichert, Martin, Luengo-Gil, Ginés, Sze Wah Wong, Sarah, Aimanianda, Vishukumar, Grisham, Christina, Malev, Nikita, Reddy, Shivani, Woollett, Laura, Askew, David S

“…Aspergillus fumigatus is a human-pathogenic mold that extracts nutrients from the environment or from host tissues by secreting hydrolytic enzymes. The ability…”
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Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase by Luengo-Gil, Ginés, Calvo, María Inmaculada, Martín-Villar, Ester, Águila, Sonia, Bohdan, Nataliya, Antón, Ana I., Espín, Salvador, Ayala de la Peña, Francisco, Vicente, Vicente, Corral, Javier, Quintanilla, Miguel, Martínez-Martínez, Irene

“…Antithrombin is a key inhibitor of the coagulation cascade, but it may also function as an anti-inflammatory, anti-angiogenic, anti-viral and anti-apoptotic…”
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Association of Anthracycline‐Related Cardiac Histological Lesions With NADPH Oxidase Functional Polymorphisms by Cascales, Almudena, Pastor‐Quirante, Francisco, Sánchez‐Vega, Beatriz, Luengo‐Gil, Ginés, Corral, Javier, Ortuño‐Pacheco, Guzmán, Vicente, Vicente, Peña, Francisco Ayala

“…Objective. Treatment with anthracyclines may cause cardiac dysfunction, but the sequence of anthracycline‐induced heart lesions has been incompletely…”
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Regulation of coagulation factor XI expression by microRNAs in the human liver by Salloum-Asfar, Salam, Teruel-Montoya, Raúl, Arroyo, Ana B, García-Barberá, Nuria, Chaudhry, Amarjit, Schuetz, Erin, Luengo-Gil, Ginés, Vicente, Vicente, González-Conejero, Rocío, Martínez, Constantino

“…High levels of factor XI (FXI) increase the risk of thromboembolic disease. However, the genetic and environmental factors regulating FXI expression are still…”
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Circulating small-sized endothelial microparticles as predictors of clinical outcome after chemotherapy for breast cancer: an exploratory analysis by García Garre, Elisa, Luengo Gil, Ginés, Montoro García, Silvia, Gonzalez Billalabeitia, Enrique, Zafra Poves, Marta, García Martinez, Elena, Roldán Schilling, Vanessa, Navarro Manzano, Esther, Ivars Rubio, Alejandra, Lip, Gregory Y. H., Ayala de la Peña, Francisco

“…Purpose Therapeutic exploitation of angiogenesis in breast cancer has been limited by the lack of reliable biomarkers. Circulating small-sized endothelial…”
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Role of Genetic Polymorphisms in NFKB -Mediated Inflammatory Pathways in Response to Primary Chemoradiation Therapy for Rectal Cancer by Dzhugashvili, Maia, MD, Luengo-Gil, Ginés, MSc, García, Teresa, MD, PhD, González-Conejero, Rocío, PhD, Conesa-Zamora, Pablo, PhD, Escolar, Pedro Pablo, MD, Calvo, Felipe, MD, PhD, Vicente, Vicente, MD, PhD, Ayala de la Peña, Francisco, MD, PhD

“…Purpose To investigate whether polymorphisms of genes related to inflammation are associated with pathologic response (primary endpoint) in patients with…”
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Identification of Thrombosis-Related Genes in Patients with Advanced Gastric Cancer: Data from AGAMENON-SEOM Registry by Zaragoza-Huesca, David, Garrido-Rodríguez, Pedro, Jiménez-Fonseca, Paula, Martínez de Castro, Eva, Sánchez-Cánovas, Manuel, Visa, Laura, Custodio, Ana, Fernández-Montes, Ana, Peñas-Martínez, Julia, Morales Del Burgo, Patricia, Gallego, Javier, Luengo-Gil, Ginés, Vicente, Vicente, Martínez-Martínez, Irene, Carmona-Bayonas, Alberto

“…Advanced gastric cancer is one of the most thrombogenic neoplasms. However, genetic mechanisms underlying this complication remain obscure, and the molecular…”
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Anti-Tumor Functions of Prelatent Antithrombin on Glioblastoma Multiforme Cells by Peñas-Martínez, Julia, Luengo-Gil, Ginés, Espín, Salvador, Bohdan, Nataliya, Ortega-Sabater, Carmen, Ródenas, Maria Carmen, Zaragoza-Huesca, David, López-Andreo, María José, Plasencia, Carme, Vicente, Vicente, Carmona-Bayonas, Alberto, Martínez-Martínez, Irene

“…Antithrombin, the main physiological inhibitor of the coagulation cascade, exerts anti-tumor effects on glioblastoma multiforme cells. Antithrombin has…”
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Corrigendum to “Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway” [Biomed. Pharmacother. 175 (2024) 116785] by Alburquerque-González, Begoña, Montoro-García, Silvia, Bernabé-García, Ángel, Bernabé-García, Manuel, Campioni-Rodrigues, Priscila, Rodríguez-Martínez, Alejandro, Luque, Irene, Salo, Tuula, Pérez-Garrido, Alfonso, Pérez-Sánchez, Horacio, Cayuela, María Luisa, Luengo-Gil, Ginés, Luchinat, Enrico, Postigo-Corrales, Fatima, Staderini, Tommaso, Nicolás, Francisco José, Conesa-Zamora, Pablo

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Potential Utility of Induced Translocation of Engineered Bacteria as a Therapeutic Agent for Mounting a Personalized Neoantigen‐Based Tumor Immune Response by Luengo‐Gil, Ginés, Conesa‐Zamora, Pablo

“…Today, an unprecedented understanding of the cancer genome, along with major breakthroughs in oncoimmunotherapy, and a resurgence of nucleic acid vaccines…”
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Transcriptomic rationale for synthetic lethality‐targeting ERCC1 and CDKN1A in chronic myelomonocytic leukaemia by Hurtado, Ana M., Luengo‐Gil, Gines, Chen‐Liang, Tzu H., Amaral, Fabio, Batta, Kiran, Palomo, Laura, Lumbreras, Eva, Przychodzen, Bartlomiej, Caparros, Eva, Amigo, Marıa L., Dıez‐Campelo, Maria, Zamora, Lurdes, Salido Fierrez, Eduardo J., Maciejewski, Jaroslaw P., Ortuño, Francisco J., Vicente, Vicente, del Canizo, Marıa, Sole, Francesc, Ferrer‐Marin, Francisca, Wiseman, Daniel H., Jerez, Andres

“…Summary Despite the absence of mutations in the DNA repair machinery in myeloid malignancies, the advent of high‐throughput sequencing and discovery of…”
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PB2382: EFFECTS OF ANTIFASCIN COMPOUNDS AGAINST LYMPHOMA CELLS IN VITRO by María Hurtado López, Ana, Chedas, Daniel, José Sánchez de Las Matas Garre, María, Postigo‐Corrales, Fátima, Albaladejo González, Ana, Beltrán Videla, Asunción, Torres‐Moreno, Daniel, Belén Arroyo‐Rodríguez, Ana, García‐Solano, José, Conesa‐Zamora, Pablo, Luengo‐Gil, Gines

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Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells by Rodenas, Maria Carmen, Peñas-Martínez, Julia, Pardo-Sánchez, Irene, Zaragoza-Huesca, David, Ortega-Sabater, Carmen, Peña-García, Jorge, Espín, Salvador, Ricote, Guillermo, Montenegro, Sofía, Ayala-De La Peña, Francisco, Luengo-Gil, Ginés, Nieto, Andrés, García-Molina, Francisco, Vicente, Vicente, Bernardi, Francesco, Lozano, María Luisa, Mulero, Victoriano, Pérez-Sánchez, Horacio, Carmona-Bayonas, Alberto, Martínez-Martínez, Irene

“…Hepsin is a type II transmembrane serine protease and its expression has been linked to greater tumorigenicity and worse prognosis in different tumors…”
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Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1 by Jaime Guillén, Cristina Ferrer-Orta, Mònica Buxaderas, Dolores Pérez-Sánchez, Marta Guerrero-Valero, Ginés Luengo-Gil, Joan Pous, Pablo Guerra, Juan C. Gómez-Fernández, Nuria Verdaguer, Senena Corbalán-García

“…Proteins containing C2 domains are the sensors for Ca(2+) and PI(4,5)P2 in a myriad of secretory pathways. Here, the use of a free-mounting system has enabled…”
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Angiogenic role of miR-20a in breast cancer by Luengo-Gil, Gines, Gonzalez-Billalabeitia, Enrique, Perez-Henarejos, Sergio Alejo, Navarro Manzano, Esther, Chaves-Benito, Asuncion, Garcia-Martinez, Elena, Garcia-Garre, Elisa, Vicente, Vicente, Ayala de la Peña, Francisco

“…Angiogenesis is a key process for tumor progression and a target for treatment. However, the regulation of breast cancer angiogenesis and its relevance for…”
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