Search Results - "Luelmo, Saskia A. C."

UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients by Hulshof, Emma C., de With, Mirjam, de Man, Femke M., Creemers, Geert-Jan, Deiman, Birgit A.L.M., Swen, Jesse J., Houterman, Saskia, Koolen, Stijn L.W., Bins, Sander, Thijs, Anna M.J., Laven, Marjan M.J., Hövels, Anke M., Luelmo, Saskia A.C., Houtsma, Danny, Shulman, Katerina, McLeod, Howard L., van Schaik, Ron H.N., Guchelaar, Henk-Jan, Mathijssen, Ron H.J., Gelderblom, Hans, Deenen, Maarten J.

“…To determine the safety, feasibility, pharmacokinetics, and cost of UGT1A1 genotype-guided dosing of irinotecan. In this prospective, multicentre,…”
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Serum miR-373-3p and miR-194-5p Are Associated with Early Tumor Progression during FOLFIRINOX Treatment in Pancreatic Cancer Patients: A Prospective Multicenter Study by van der Sijde, Fleur, Homs, Marjolein Y V, van Bekkum, Marlies L, van den Bosch, Thierry P P, Bosscha, Koop, Besselink, Marc G, Bonsing, Bert A, de Groot, Jan Willem B, Karsten, Thomas M, Groot Koerkamp, Bas, Haberkorn, Brigitte C M, Luelmo, Saskia A C, Mekenkamp, Leonie J M, Mustafa, Dana A M, Wilmink, Johanna W, van Eijck, Casper H J, Vietsch, Eveline E, On Behalf Of The Dutch Pancreatic Cancer Group

“…In this study, we explored the predictive value of serum microRNA (miRNA) expression for early tumor progression during FOLFIRINOX chemotherapy and its…”
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Serum cytokine levels are associated with tumor progression during FOLFIRINOX chemotherapy and overall survival in pancreatic cancer patients by van der Sijde, Fleur, Dik, Willem A, Mustafa, Dana A M, Vietsch, Eveline E, Besselink, Marc G, Debets, Reno, Koerkamp, Bas Groot, Haberkorn, Brigitte C M, Homs, Marjolein Y V, Janssen, Quisette P, Luelmo, Saskia A C, Mekenkamp, Leonie J M, Oostvogels, Astrid A M, Smits-Te Nijenhuis, Marja A W, Wilmink, Johanna W, van Eijck, Casper H J

“…Biomarkers predicting treatment response may be used to stratify patients with pancreatic ductal adenocarcinoma (PDAC) for available therapies. The aim of this…”
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Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report by van Olden, Mechteld C.S., de Jong-Hesse, Yvonne, Vollebregt, Tessa, de Groot, Stefanie, Luelmo, Saskia A.C., Marinkovic, Marina

“…Abstract Introduction: In this paper, we report a case of visual impairment during treatment with sunitinib in a patient with metastatic renal cell carcinoma…”
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Circulating TP53 mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX by van der Sijde, Fleur, Azmani, Zakia, Besselink, Marc G., Bonsing, Bert A., de Groot, Jan Willem B., Groot Koerkamp, Bas, Haberkorn, Brigitte C. M., Homs, Marjolein Y. V., van IJcken, Wilfred F. J., Janssen, Quisette P., Lolkema, Martijn P., Luelmo, Saskia A. C., Mekenkamp, Leonie J. M., Mustafa, Dana A. M., van Schaik, Ron H. N., Wilmink, Johanna W., Vietsch, Eveline E., van Eijck, Casper H. J.

“…Background: Biomarkers predicting treatment response may be used to stratify pancreatic ductal adenocarcinoma (PDAC) patients for therapy. The aim of this…”
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Preoperative Chemoradiotherapy Versus Immediate Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Results of the Dutch Randomized Phase III PREOPANC Trial by Versteijne, Eva, Suker, Mustafa, Groothuis, Karin, Akkermans-Vogelaar, Janine M, Besselink, Marc G, Bonsing, Bert A, Buijsen, Jeroen, Busch, Olivier R, Creemers, Geert-Jan M, van Dam, Ronald M, Eskens, Ferry A L M, Festen, Sebastiaan, de Groot, Jan Willem B, Groot Koerkamp, Bas, de Hingh, Ignace H, Homs, Marjolein Y V, van Hooft, Jeanin E, Kerver, Emile D, Luelmo, Saskia A C, Neelis, Karen J, Nuyttens, Joost, Paardekooper, Gabriel M R M, Patijn, Gijs A, van der Sangen, Maurice J C, de Vos-Geelen, Judith, Wilmink, Johanna W, Zwinderman, Aeilko H, Punt, Cornelis J, van Eijck, Casper H, van Tienhoven, Geertjan

“…Preoperative chemoradiotherapy may improve the radical resection rate for resectable or borderline resectable pancreatic cancer, but the overall benefit is…”
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Neoadjuvant Chemoradiotherapy Versus Upfront Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Long-Term Results of the Dutch Randomized PREOPANC Trial by Versteijne, Eva, van Dam, Jacob L, Suker, Mustafa, Janssen, Quisette P, Groothuis, Karin, Akkermans-Vogelaar, Janine M, Besselink, Marc G, Bonsing, Bert A, Buijsen, Jeroen, Busch, Olivier R, Creemers, Geert-Jan M, van Dam, Ronald M, Eskens, Ferry A L M, Festen, Sebastiaan, de Groot, Jan Willem B, Groot Koerkamp, Bas, de Hingh, Ignace H, Homs, Marjolein Y V, van Hooft, Jeanin E, Kerver, Emile D, Luelmo, Saskia A C, Neelis, Karen J, Nuyttens, Joost, Paardekooper, Gabriel M R M, Patijn, Gijs A, van der Sangen, Maurice J C, de Vos-Geelen, Judith, Wilmink, Johanna W, Zwinderman, Aeilko H, Punt, Cornelis J, van Tienhoven, Geertjan, van Eijck, Casper H J

“…The benefit of neoadjuvant chemoradiotherapy in resectable and borderline resectable pancreatic cancer remains controversial. Initial results of the PREOPANC…”
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Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up by Klatte, Derk C F, Boekestijn, Bas, Wasser, Martin N J M, Feshtali Shahbazi, Shirin, Ibrahim, Isaura S, Mieog, J Sven D, Luelmo, Saskia A C, Morreau, Hans, Potjer, Thomas P, Inderson, Akin, Boonstra, Jurjen J, Dekker, Friedo W, Vasen, Hans F A, van Hooft, Jeanin E, Bonsing, Bert A, van Leerdam, Monique E

“…Pancreatic cancer surveillance in high-risk individuals may lead to detection of pancreatic ductal adenocarcinoma (PDAC) at an earlier stage and with improved…”
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Surveillance for Pancreatic Cancer in High-Risk Individuals Leads to Improved Outcomes: A Propensity Score-Matched Analysis by Klatte, Derk C.F., Boekestijn, Bas, Onnekink, Anke M., Dekker, Friedo W., van der Geest, Lydia G., Wasser, Martin N.J.M., Feshtali, Shirin, Mieog, J. Sven D., Luelmo, Saskia A.C., Morreau, Hans, Potjer, Thomas P., Inderson, Akin, Boonstra, Jurjen J., Vasen, Hans F.A., van Hooft, Jeanin E., Bonsing, Bert A., van Leerdam, Monique E.

“…Recent pancreatic cancer surveillance programs of high-risk individuals have reported improved outcomes. This study assessed to what extent outcomes of…”
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Increasing Systemic Immune-Inflammation Index During Treatment in Patients with Advanced Pancreatic Cancer is Associated with Poor Survival – A Retrospective, Multicenter, Cohort Study by Van ‘t Land, Freek R., Aziz, Mohammad H., Michiels, Nynke, Mieog, J. Sven D., Bonsing, Bert A., Luelmo, Saskia A.C., Homs, Marjolein Y.V., Groot Koerkamp, Bas, Papageorgiou, Grigorios, van Eijck, Casper H.J.

“…A high systemic immune-inflammation index (SIII) at diagnosis of various cancers, including pancreatic cancer, is associated with poor prognosis. The impact of…”
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Incidence, timing and risk factors of venous thromboembolic events in patients with pancreatic cancer by Hanna-Sawires, Randa G., Groen, Jesse V., Hamming, Alexander, Tollenaar, Rob A.E.M., Mesker, Wilma E., Luelmo, Saskia A.C., Vahrmeijer, Alexander L., Bonsing, Bert A., Versteeg, Henri H., Klok, F.A., Mieog, J.Sven D.

“…Pancreatic cancer is associated with a high risk of venous thromboembolism (VTE). However, comprehensive data on incidence, timing and relevant determinants of…”
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The prognostic value of the 12‐, 6‐, 3‐ and 1‐month ‘Surprise Question’ in cancer patients: A prospective cohort study in three hospitals by Stoppelenburg, Arianne, Arslan, Müzeyyen, Owusuaa, Catherine, Gunnink, Nicolette, Linden, Yvette M., Luelmo, Saskia A. C., Meerum‐Terwogt, Jetske, Padt‐Pruijsten, Annemieke, Nieboer, Daan, Heide, Agnes

“…Objective This prospective study aimed to evaluate the performance of the ‘Surprise Question’ (SQ) ‘Would I be surprised if this patient died in the next 12…”
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Lifetime Transfusion Burden and Transfusion‐Related Iron Overload in Adult Survivors of Solid Malignancies by Woei‐A‐Jin, F.J. Sherida H., Zheng, Shu Zhen, Kiliçsoy, Inci, Hudig, Francisca, Luelmo, Saskia A.C., Kroep, Judith R., Lamb, Hildo J., Osanto, Susanne

“…Background Limited data exist on transfusion burden and transfusion‐related iron overload in adult survivors of solid malignancies. Methods Hospital‐specific…”
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Timing of start of systemic treatment in patients with asymptomatic metastasized pancreatic cancer (TIMEPAN): a protocol of a multicenter prospective patient preference non-randomized trial by Augustinus, Simone, Broekman, Thijmen, Creemers, Geert-Jan, Daamen, Lois A, van Dieren, Susan, de Groot, Jan-Willem B, Cirkel, Geert A, Homs, Marjolein Y V, van Laarhoven, Hanneke W M, van Leeuwen, Lobke, Los, Maartje, Luelmo, Saskia A C, van Oijen, Martijn G H, Spierings, Leontine E A M, de Vos-Geelen, Judith, Besselink, Marc G, Wilmink, Johanna W

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Targeted next-generation sequencing of FNA-derived DNA in pancreatic cancer by Sibinga Mulder, Babs G, Mieog, J Sven D, Handgraaf, Henricus J M, Farina Sarasqueta, Arantza, Vasen, Hans F A, Potjer, Thomas P, Swijnenburg, Rutger-Jan, Luelmo, Saskia A C, Feshtali, Shirin, Inderson, Akin, Vahrmeijer, Alexander L, Bonsing, Bert A, van Wezel, Tom, Morreau, Hans

“…To improve the diagnostic value of fine-needle aspiration (FNA)-derived material, we perform targeted next-generation sequencing (NGS) in patients with a…”
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Identifying the Need to Discuss Infertility Concerns Affecting Testicular Cancer Patients: An Evaluation (INDICATE Study) by Krouwel, Esmée M, Jansen, Thijs G, Nicolai, Melianthe P J, Dieben, Sandra W M, Luelmo, Saskia A C, Putter, Hein, Pelger, Rob C M, Elzevier, Henk W

“…Men with testicular cancer (TC) risk impaired fertility. Fertility is a major concern for TC patients due to diagnosis in almost always reproductive ages and…”
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The impact of cancer treatment on quality of life in patients with pancreatic and periampullary cancer: a propensity score matched analysis by Mackay, Tara M., Dijksterhuis, Willemieke P.M., Latenstein, Anouk E.J., van der Geest, Lydia G., Sprangers, Mirjam A.G., van Eijck, Casper H.J., Homs, Marjolein Y.V., Luelmo, Saskia A.C., Molenaar, I. Quintus, van Santvoort, Hjalmar, Schreinemakers, Jennifer M.J., Wilmink, Johanna W., Besselink, Marc G., van Laarhoven, Hanneke W., van Oijen, Martijn G.H.

“…The impact of pancreatic and periampullary cancer treatment on health-related quality of life (HRQoL) is unclear. This study merged data from the Netherlands…”
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Overview and Future Perspectives on Tumor-Targeted Positron Emission Tomography and Fluorescence Imaging of Pancreatic Cancer in the Era of Neoadjuvant Therapy by van Dam, Martijn A., Vuijk, Floris A., Stibbe, Judith A., Houvast, Ruben D., Luelmo, Saskia A. C., Crobach, Stijn, Shahbazi Feshtali, Shirin, de Geus-Oei, Lioe-Fee, Bonsing, Bert A., Sier, Cornelis F. M., Kuppen, Peter J. K., Swijnenburg, Rutger-Jan, Windhorst, Albert D., Burggraaf, Jacobus, Vahrmeijer, Alexander L., Mieog, J. Sven D.

“…Background: Despite recent advances in the multimodal treatment of pancreatic ductal adenocarcinoma (PDAC), overall survival remains poor with a 5-year…”
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Diagnostic value of targeted next-generation sequencing in patients with suspected pancreatic or periampullary cancer by Sibinga Mulder, Babs G, Mieog, J Sven D, Farina Sarasqueta, Arantza, Handgraaf, Henricus Jm, Vasen, Hans F A, Swijnenburg, Rutger-Jan, Luelmo, Saskia A C, Feshtali, Shirin, Inderson, Akin, Vahrmeijer, Alexander L, Bonsing, Bert A, Wezel, Tom van, Morreau, Hans

“…Radiological imaging and morphological assessment of cytology material have limitations for preoperative classification of pancreatic or periampullary lesions,…”
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The self-perceived palliative care barriers and educational needs of clinicians working in hospital primary care teams and referral patterns: lessons learned from a single-center survey and cohort study by van der Stap, Lotte, de Nijs, Ellen J M, Oomes, Marleen, Juffermans, Carla C M, Ravensbergen, Willeke M, Luelmo, Saskia A C, Horeweg, Nanda, van der Linden, Yvette M

“…Within the generalist-plus-specialist palliative care model, palliative care is mainly provided by nurses and physicians of hospital primary care teams…”
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