Search Results - "Luebbert, Christian"

Influence of bound dodecanoic acid on the reconstitution of albumin nanoparticles from a lyophilized state by Luebbert, Christian C. E., Mansa, Rola, Rahman, Raisa, Jakubek, Zygmunt J., Frahm, Grant E., Zou, Shan, Johnston, Michael J. W.

“…The development of reference standards for nanoparticle sizing allows for cross laboratory studies and effective transfer of particle sizing methodology. To…”
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Amorphous-Amorphous Phase Separation in API/Polymer Formulations by Luebbert, Christian, Huxoll, Fabian, Sadowski, Gabriele

“…The long-term stability of pharmaceutical formulations of poorly-soluble drugs in polymers determines their bioavailability and therapeutic applicability…”
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Predicting Deliquescence Relative Humidities of Crystals and Crystal Mixtures by Veith, Heiner, Luebbert, Christian, Sadowski, Gabriele

“…The presence of water in the form of relative humidity (RH) may lead to deliquescence of crystalline components above a certain RH, the deliquescence RH (DRH)…”
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Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose by Luebbert, Christian, Stoyanov, Edmont

“…Amorphous solid dispersion (ASD) formulations are preferred enabling formulations for poorly water soluble active pharmaceutical ingredients (API) as they…”
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Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer cell by Gobin, Jonathan, Muradia, Gauri, Mehic, Jelica, Westwood, Carole, Couvrette, Lauren, Stalker, Andrew, Bigelow, Stewart, Luebbert, Christian C, Bissonnette, Frédéric St-Denis, Johnston, Michael J W, Sauvé, Simon, Tam, Roger Y, Wang, Lisheng, Rosu-Myles, Michael, Lavoie, Jessie R

“…Extracellular vesicles (EVs) produced by human bone marrow-derived mesenchymal stromal cells (hBM-MSCs) are currently investigated for their clinical…”
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Swelling and Diffusion in Polymerized Ionic Liquids-Based Hydrogels by Jastram, Ann, Lindner, Tobias, Luebbert, Christian, Sadowski, Gabriele, Kragl, Udo

“…Hydrogels are one of the emerging classes of materials in current research. Besides their numerous applications in the medical sector as a drug delivery system…”
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Phase behavior of ASDs based on hydroxypropyl cellulose by Luebbert, Christian, Stoyanov, Edmont, Sadowski, Gabriele

“…Novel polymeric carriers for amorphous solid dispersions (ASDs) are highly demanded in pharmaceutical industry to improve the bioavailability of poorly-soluble…”
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Nanoparticle size and production efficiency are affected by the presence of fatty acids during albumin nanoparticle fabrication by Luebbert, Christian C, Clarke, Tessa M, Pointet, Roberta, Frahm, Grant E, Tam, Sharon, Lorbetskie, Barry, Sauvé, Simon, Johnston, Michael J W

“…We have previously identified extensive glycation, bound fatty acids and increased quantities of protein aggregates in commercially available recombinant HSA…”
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The shelf life of ASDs: 2. Predicting the shelf life at storage conditions by Wolbert, Friederike, Luebbert, Christian, Sadowski, Gabriele

“…Amorphous solid dispersions (ASDs) are a widely used formulation technology for poorly water-soluble active pharmaceutical ingredients (API). Depending on the…”
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Stability of Pharmaceutical Co-Crystals at Humid Conditions Can Be Predicted by Veith, Heiner, Zaeh, Maximilian, Luebbert, Christian, Rodríguez-Hornedo, Naír, Sadowski, Gabriele

“…Knowledge of the stability of pharmaceutical formulations against relative humidity (RH) is essential if they are to become pharmaceutical products. The…”
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A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles by Munshi, Afnan, Mehic, Jelica, Creskey, Marybeth, Gobin, Jonathan, Gao, Jun, Rigg, Emma, Muradia, Gauri, Luebbert, Christian C, Westwood, Carole, Stalker, Andrew, Allan, David S, Johnston, Michael J W, Cyr, Terry, Rosu-Myles, Michael, Lavoie, Jessie R

“…Clinical applications have shown extracellular vesicles (EVs) to be a major paracrine effector in therapeutic responses produced by human mesenchymal…”
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Factors Influencing the Crystallization-Onset Time of Metastable ASDs by Wolbert, Friederike, Fahrig, Ineke-Katharina, Gottschalk, Tobias, Luebbert, Christian, Thommes, Markus, Sadowski, Gabriele

“…In formulation development, amorphous solid dispersions (ASD) are considered to improve the bioavailability of poorly water-soluble active pharmaceutical…”
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Predicting process design spaces for spray drying amorphous solid dispersions by Dohrn, Stefanie, Rawal, Pranay, Luebbert, Christian, Lehmkemper, Kristin, Kyeremateng, Samuel O., Degenhardt, Matthias, Sadowski, Gabriele

“…Amorphous solid dispersions (ASDs) are commonly manufactured using spray-drying processes. The product quality can be decisively influenced by the choice of…”
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Microfluidic filtration and extraction of pathogens from food samples by hydrodynamic focusing and inertial lateral migration by Clime, Liviu, Hoa, Xuyen D., Corneau, Nathalie, Morton, Keith J., Luebbert, Christian, Mounier, Maxence, Brassard, Daniel, Geissler, Matthias, Bidawid, Sabah, Farber, Jeff, Veres, Teodor

“…Detecting pathogenic bacteria in food or other biological samples with lab-on-a-chip (LOC) devices requires several sample preparation steps prior to analysis…”
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Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of Campylobacter jejuni by Taboada, Eduardo N, Mackinnon, Joanne M, Luebbert, Christian C, Gannon, Victor P J, Nash, John H E, Rahn, Kris

“…Multi-Locus Sequence Typing (MLST) has emerged as a leading molecular typing method owing to its high ability to discriminate among bacterial isolates, the…”
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Moisture-induced phase separation and recrystallization in amorphous solid dispersions by Luebbert, Christian, Sadowski, Gabriele

“…[Display omitted] Active Pharmaceutical Ingredients (APIs) are often dissolved in polymeric matrices to control the gastrointestinal dissolution and to…”
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A new approach for the analysis of bacterial microarray-based Comparative Genomic Hybridization: insights from an empirical study by Taboada, Eduardo N, Acedillo, Rey R, Luebbert, Christian C, Findlay, Wendy A, Nash, John H E

“…Microarray-based Comparative Genomic Hybridization (M-CGH) has been used to characterize the extensive intraspecies genetic diversity found in bacteria at the…”
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Comparative genomics profiling of clinical isolates of Aeromonas salmonicida using DNA microarrays by Nash, John H E, Findlay, Wendy A, Luebbert, Christian C, Mykytczuk, Oksana L, Foote, Simon J, Taboada, Eduardo N, Carrillo, Catherine D, Boyd, Jessica M, Colquhoun, Duncan J, Reith, Michael E, Brown, Laura L

“…Aeromonas salmonicida has been isolated from numerous fish species and shows wide variation in virulence and pathogenicity. As part of a larger research…”
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In-situ determination of crystallization kinetics in ASDs via water sorption experiments by Luebbert, Christian, Sadowski, Gabriele

“…[Display omitted] Amorphous solid dispersions (ASD) are intended to improve the bioavailability of poorly water-soluble active pharmaceutical ingredients…”
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A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over-expression in neuro-progenitor cells by Lei, Joy X, Cassone, Cristina G, Luebbert, Christian, Liu, Qing Yan

“…Molecular changes in multiple biological processes contribute to the development of chronic neurodegeneration such as late onset Alzheimer's disease (LOAD). To…”
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