Search Results - "Lue, L"

What happens to microglial TREM2 in Alzheimer’s disease: Immunoregulatory turned into immunopathogenic? by Lue, L.-F, Schmitz, C, Walker, D.G

“…Highlights • Mutations in TREM2 gene increase the risk of several neurodegenerative diseases. • As a phagocytic receptor, TREM2 also regulates inflammatory…”
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Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer’s disease brains and human microglia by Walker, D.G, Whetzel, A.M, Lue, L.-F

“…Highlights • We identified SOCS-1 through SOCS-7 and CIS mRNA expression in human brains. • We identified SOCS-1 through SOCS-7 protein expression in human…”
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DynamO: a free O(N) general event-driven molecular dynamics simulator by Bannerman, M N, Sargant, R, Lue, L

“…Molecular dynamics algorithms for systems of particles interacting through discrete or "hard" potentials are fundamentally different to the methods for…”
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The electric double layer at high surface potentials: The influence of excess ion polarizability by Hatlo, M. M, van Roij, R, Lue, L

“…By including the excess ion polarizability into the Poisson-Boltzmann theory, we show that the decrease in differential capacitance with voltage, observed for…”
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p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer’s disease by Yao, X-Q, Jiao, S-S, Saadipour, K, Zeng, F, Wang, Q-H, Zhu, C, Shen, L-L, Zeng, G-H, Liang, C-R, Wang, J, Liu, Y-H, Hou, H-Y, Xu, X, Su, Y-P, Fan, X-T, Xiao, H-L, Lue, L-F, Zeng, Y-Q, Giunta, B, Zhong, J-H, Walker, D G, Zhou, H-D, Tan, J, Zhou, X-F, Wang, Y-J

“…In Alzheimer’s disease (AD), neurodegenerative signals such as amyloid-beta (Aβ) and the precursors of neurotrophins, outbalance neurotrophic signals, causing…”
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A molecular approach to bioseparations: Protein–protein and protein–salt interactions by Curtis, R.A., Lue, L.

“…Many bioprocess separations involve manipulating the solution conditions to selectively remove or concentrate a target protein. The selectivity is determined…”
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Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases by Walker, D.G., Lue, L-F.

“…Inflammation‐mediated mechanisms for human neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) have evolved from being on…”
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Electrostatic interactions of charged bodies from the weak- to the strong-coupling regime by Hatlo, M. M, Lue, L

“…A simple field theory approach is developed to model the properties of charged, dielectric bodies and their associated counterions. This predictive theory is…”
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A variational field theory for solutions of charged, rigid particles by Lue, L.

“…A general field theoretic formalism is developed for dealing with solutions of particles with rigid charge distributions. Combined with the mean-field…”
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Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease by Lue, Lih-Fen, Kuo, Yu-Min, Roher, Alex E., Brachova, Libuse, Shen, Yong, Sue, Lucia, Beach, Thomas, Kurth, Janice H., Rydel, Russel E., Rogers, Joseph

“…We have characterized amyloid β peptide (Aβ. concentration, Aβ deposition, paired helical filament formation, cerebrovascular amyloid angiopathy,…”
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Modeling microglial activation in Alzheimer’s disease with human postmortem microglial cultures by Lue, Lih-Fen, Walker, Douglas G., Rogers, Joseph

“…Alzheimer’s disease (AD) is a uniquely human disorder. Despite intense research, the lack of availability of model systems has hindered AD studies though in…”
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Electrostatic depletion forces between planar surfaces by Hatlo, M M, Curtis, R A, Lue, L

“…The interaction between two dielectric plates immersed in an electrolyte solution is examined by using a variational perturbation approximation for the grand…”
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Interphase of a Polymer at a Solid Interface by Butt, H. J, Duran, H, Egger, W, Faupel, F, Harmandaris, V, Harms, S, Johnston, K, Kremer, K, Lin, F. Y, Lue, L, Ohrt, C, Raetzke, K, Ravelli, L, Steffen, W, Vianna, S. D. B

“…Atomistic molecular dynamics simulations of a chemically realistic model of atactic short-chain polystyrene between gold surfaces (111) and positron…”
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Molecular dynamics study of the thermodynamics and transport coefficients of hard hyperspheres in six and seven dimensions by Lue, L, Bishop, Marvin

“…Molecular dynamics (MD) simulations are performed for six- and seven-dimensional hard-hypersphere fluids. The equation of state, velocity autocorrelation…”
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Electrolytes at spherical dielectric interfaces by Curtis, R A, Lue, L

“…A variational theory is developed and applied to study the properties of dielectric spheres immersed in a symmetric electrolyte solution. In the limit that the…”
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Consequences of Aberrant Insulin Regulation in the Brain: Can Treating Diabetes be Effective for Alzheimers Disease by Arab, L, Sadeghi, R, Walker, D G, Lue, L-F, Sabbagh, M N

“…There is an urgent need for new ways to treat Alzheimers disease (AD), the most common cause of dementia in the elderly. Current therapies are modestly…”
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DynamO: a free ${cal O}$(N) general event-driven molecular dynamics simulator by Bannerman, M. N., Sargant, R., Lue, L.

“…Molecular dynamics algorithms for systems of particles interacting through discrete or “hard” potentials are fundamentally different to the methods for…”
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Migration from low- to high-risk countries: a qualitative study of perceived risk of breast cancer and the influence on participation in mammography screening among migrant women in Denmark by Kristiansen, M., Lue-Kessing, L., Mygind, A., Razum, O., Norredam, M.

“…Migrants are less likely to participate in mammography screening programmes compared with local‐born populations in Europe. We explored perceptions of breast…”
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Volumetric Behavior of Athermal Dendritic Polymers:  Monte Carlo Simulation by Lue, L

“…We present results of Monte Carlo simulations for dilute to concentrated solutions of athermal, homogeneous dendritic polymers. The dendritic polymers are…”
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Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease by Lue, L-F, Yan, S D, Stern, D M, Walker, D G

“…Receptor for advanced glycation endproducts (RAGE), a member of the immunoglobulin superfamily, is a multi-ligand, cell surface receptor expressed by neurons,…”
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