Search Results - "Ludtke, Diogo Seibert"
-
1
Proton-Transfer-Based Azides with Fluorescence Off–On Response for Detection of Hydrogen Sulfide: An Experimental, Theoretical, and Bioimaging Study
Published in Journal of organic chemistry (21-12-2018)“…This work describes the synthesis of photoactive proton transfer compounds based on the benzazolic core containing the azide group. The compounds present…”
Get full text
Journal Article -
2
Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives
Published in Bioorganic & medicinal chemistry (01-11-2018)“…[Display omitted] •New hybrids tacrine-carbohydrate derivatives were synthesized.•Molecular docking studies were performed.•All compounds were found to be…”
Get full text
Journal Article -
3
Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling
Published in MedChemComm (01-12-2019)“…In this study, we synthesized nine novel hybrids derived from d -xylose, d -ribose, and d -galactose sugars connected by a methylene chain with lophine. The…”
Get full text
Journal Article -
4
Selenofuranoside Ameliorates Memory Loss in Alzheimer-Like Sporadic Dementia: AChE Activity, Oxidative Stress, and Inflammation Involvement
Published in Oxidative medicine and cellular longevity (01-01-2015)“…Alzheimer’s disease (AD) is becoming more common due to the increase in life expectancy. This study evaluated the effect of selenofuranoside (Se) in an…”
Get full text
Journal Article -
5
Reaction of Acyl Chlorides with In Situ Formed Zinc Selenolates: Synthesis of Selenoesters versus Ring-Opening Reaction of Tetrahydrofuran
Published in Journal of chemistry (01-01-2016)“…Attempting to apply the in situ production of PhSeZnSePh to the synthesis of selenoesters, an unexpected reaction involving the solvent (tetrahydrofuran) was…”
Get full text
Journal Article -
6
Proposal of a new, fast, cheap, and easy method using DLLME for extraction and preconcentration of diazepam and its transformation products generated by a solar photo-Fenton process
Published in Water research (Oxford) (01-10-2020)“…•New diazepam Transformation Products (TPs) generated by solar photo-Fenton.•Degradation pathways with new diazepam TPs were first proposed.•DLLME…”
Get full text
Journal Article -
7
Effects of organic and inorganic selenium supplementation on frozen-thawed ram semen at two cooling periods
Published in Veterinary research communications (01-06-2024)“…The aim of this study was to evaluate the effects of different selenium compounds on the sperm quality of cryopreserved ram semen. Ejaculates from four rams,…”
Get full text
Journal Article -
8
Protective effects of octylseleno-xylofuranoside in a streptozotocin-induced mouse model of Alzheimer's disease
Published in European journal of pharmacology (05-11-2021)“…Octylseleno-xylofuranoside (OSX) is an organic selenium compound which has previously shown antioxidant and antidepressant-like activities, trough the…”
Get full text
Journal Article -
9
Selenofuranoside improves long-term memory deficits in rats after exposure to monosodium glutamate: Involvement of Na+, K+-ATPase activity
Published in Physiology & behavior (01-02-2018)“…Monosodium glutamate (MSG) is the most widely used additive in the food industry; however, some adverse effects of this additive, including functional,…”
Get full text
Journal Article -
10
Glycoconjugates Based on Supramolecular Tröger's Base Scaffold: Synthesis, Photophysics, Docking, and BSA Association Study
Published in ACS omega (20-08-2019)“…This study presents new Tröger's bases bearing glycosyl moieties obtained from a copper-catalyzed azide-alkyne cycloaddition reaction. The Tröger's bases…”
Get full text
Journal Article -
11
Glycoconjugates Based on Supramolecular Tröger’s Base Scaffold: Synthesis, Photophysics, Docking, and BSA Association Study
Published in ACS omega (20-08-2019)“…This study presents new Tröger’s bases bearing glycosyl moieties obtained from a copper-catalyzed azide–alkyne cycloaddition reaction. The Tröger’s bases…”
Get full text
Journal Article -
12
Catálise assimétrica no Brasil: desenvolvimento e potencialidades para o avanço da indústria química brasileira
Published in Química Nova (2013)“…The preparation of enantiomerically pure or enriched substances is of fundamental importance to pharmaceutical, food, agrochemical, and cosmetics industries…”
Get full text
Journal Article -
13
Cadmium inhibits the ovary [delta]-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside
Published in Journal of applied toxicology (01-07-2013)“…Cadmium (Cd) toxicity is a concern to the tobacco-smoking sub-population which includes millions of people worldwide. Although this metal may cause severe…”
Get full text
Journal Article -
14
Synthesis of new lophine–carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling† †Electronic supplementary information (ESI) available: Graphics and extra data of in vitro and in silico experiments and detailed spectroscopic characterization. See DOI: 10.1039/c9md00358d
Published in MedChemComm (08-11-2019)“…A series of selective butyrylcholinesterase inhibitors were obtained. The absence of in vitro cytotoxicity and good ADME-Tox profile make these compounds new…”
Get full text
Journal Article -
15
Cadmium inhibits the ovary δ-aminolevulinate dehydratase activity in vitro and ex vivo: protective role of seleno-furanoside
Published in Journal of applied toxicology (01-07-2013)“…ABSTRACT Cadmium (Cd) toxicity is a concern to the tobacco‐smoking sub‐population which includes millions of people worldwide. Although this metal may cause…”
Get full text
Journal Article