Search Results - "Ludowyke, R I"

Antigen-induced Secretion of Histamine and the Phosphorylation of Myosin by Protein Kinase C in Rat Basophilic Leukemia Cells by Ludowyke, R I, Peleg, I, Beaven, M A, Adelstein, R S

“…IgE-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells results in the secretion of histamine. Myosin immunoprecipitated from these cells shows an…”
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Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells by WILSON, J. R, BIDEN, T. J, LUDOWYKE, R. I

“…Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and…”
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Mechanism of action of endothelin in rat cardiac muscle: cross-bridge kinetics and myosin light chain phosphorylation by Rossmanith, Gunther H., Hoh, Joseph F. Y., Turnbull, Lynne, Ludowyke, Russell I.

“…1. The molecular mechanism of inotropic action of endothelin was investigated in rat ventricular muscle by studying its effects on characteristics of isometric…”
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ATP gamma S induces actin and myosin rearrangement during histamine secretion in a rat basophilic leukemia cell line (RBL-2H3) by Ludowyke, R I, Kawasugi, K, French, P W

“…Rat basophilic leukemia cells (RBL-2H3) undergo morphological and cytoskeletal changes during antigen (DNP-BSA) or calcium ionophore-induced secretion of…”
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Evidence that IgE Receptor Stimulation Increases Adenosine Release from Rat Basophilic Leukaemia (RBL-2H3) Cells by Lloyd, H G.E, Ross, L, Li, KM, Ludowyke, RI

“…Adenosine may play a role in asthma by enhancing inflammatory mediator release from lung mast cells. In this study, we investigated whether adenosine is…”
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Calcium-independent secretion by ATP gamma S from a permeabilized rat basophilic leukaemia cell line (RBL-2H3) by Ludowyke, R I, Scurr, L L

“…Activation of rat basophilic leukaemia cells (RBL-2H3) leads to the secretion of allergic and inflammatory mediators. These cells can be permeabilized, yet…”
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Transient Translocation and Activation of Protein Phosphatase 2A during Mast Cell Secretion by Ludowyke, Russell I., Holst, Jeff, Mudge, Lisa-Maree, Sim, Alistair T.R.

“…Okadaic acid inhibits secretion from mast cells, suggesting a regulatory role for protein Ser/Thr phosphatases type I (PP1) and/or 2A (PP2A) in the secretory…”
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Induction of interleukin-4 and interleukin-5 expression in mast cells is inhibited by glucocorticoids by Sewell, W A, Scurr, L L, Orphanides, H, Kinder, S, Ludowyke, R I

“…Inflammation in asthma and other allergic diseases is characterized by excessive production of immunoglobulin E (IgE) and the influx of leukocytes, especially…”
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Calcium ionophore-induced secretion from mast cells correlates with myosin light chain phosphorylation by protein kinase C by Ludowyke, RI, Scurr, LL, McNally, CM

“…Rat basophilic leukemia mast cells (RBL-2H3) secrete histamine when activated by Ag. This secretion correlates with increased phosphorylation of myosin light…”
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Nutrient Stimulation Results in a Rapid Ca2+-dependent Threonine Phosphorylation of Myosin Heavy Chain in Rat Pancreatic Islets and RINm5F Cells by Wilson, Justine R., Ludowyke, Russell I., Biden, Trevor J.

“…Activation of protein kinases plays an important role in the Ca2+-dependent stimulation of insulin secretion by nutrients. The aim of the present study was to…”
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INHIBITION OF ANTIGEN AND CALCIUM IONOPHORE INDUCED SECRETION FROM RBL-2H3 CELLS BY PHOSPHATASE INHIBITORS by Ludowyke, Russell I., Warton, Krystina, Scurr, Lyndee L.

“…The role of serine/threonine protein phosphatases PP1 and PP2A in mast cell secretion was investigated using the phosphatase inhibitors okadaic acid and…”
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Proteins in the plasma membranes of rat peritoneal mast cells by Ludowyke, R I, West, G B

“…Plasma membranes of peritoneal mast cells from rats specifically bred for resistance to the dextran anaphylactoid reaction contain a polypeptide of molecular…”
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A peritoneal fluid activator for histamine release from isolated peritoneal mast cells of the rat by Ludowyke, R I, West, G

“…A factor present in rat peritoneal fluid has been found to be necessary for optimal release of histamine from peritoneal mast cells by dextran and antigen, but…”
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A possible link between the ability of rat isolated peritoneal mast cells to release histamine when challenged with dextran and the proteins in their plasma membranes by Ludowyke, R I, West, G B, Harris, J R, Hanahoe, T H

“…The plasma membranes of peritoneal mast cells from rats specifically bred for resistance to the dextran anaphylactoid reaction contain a polypeptide of…”
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Amine uptake into intact mast cell granules in vitro by Ludowyke, Russell I, Lagunoff, David

“…Histamine, the principal amine of rat peritoneal mast cells, is taken up into isolated granules with intact membranes. Uptake is pH- and…”
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The role of myosin phosphorylation in RBL-2H3 cell secretion by Peleg, I, Ludowyke, R I, Beaven, M A, Adelstein, R S

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A redistribution of actin and myosin IIA accompanies Ca(2+)-dependent insulin secretion by Wilson, J R, Ludowyke, R I, Biden, T J

“…The study addressed the functional link between remodelling of the actomyosin cytoskeleton in pancreatic beta-cells and the regulation of insulin secretion…”
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In situ phosphorylation of human platelet and rat basophilic leukemia cell (RBL-2H3) myosin heavy chain and light chain by Adelstein, R S, Beaven, M A, Bengur, A R, Kawamoto, S, Ludowyke, R I, Peleg, I, Sellers, J R

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Focal adhesion formation is associated with secretion of allergic mediators by Kawasugi, K, French, P W, Penny, R, Ludowyke, R I

“…Adherence of cells to the extracellular matrix via focal adhesions is known to modulate many cellular functions. However, the role of focal adhesions in the…”
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PMA and calcium ionophore induce myosin and F-actin rearrangement during histamine secretion from RBL-2H3 cells by Ludowyke, R I, Kawasugi, K, French, P W

“…Rat basophilic leukemia (RBL-2H3) cells undergo morphological and cytoskeletal changes during antigen-induced secretion of allergic mediators. The exact role…”
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