Search Results - "Ludewig, Fabian"
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A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease
Published in Scientific reports (08-03-2022)“…Single cell multi-omics analysis has the potential to yield a comprehensive understanding of the cellular events that underlie the basis of human diseases. The…”
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MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization
Published in Molecular biology of the cell (15-01-2012)“…The inner membrane of mitochondria is especially protein rich and displays a unique morphology characterized by large invaginations, the mitochondrial cristae,…”
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mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer
Published in PloS one (24-02-2015)“…Intrinsic and acquired resistance to the monoclonal antibody drug trastuzumab is a major problem in the treatment of HER2-positive breast cancer. A deeper…”
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The DNA Methyltransferase 1 (DNMT1) Controls the Shape and Dynamics of Migrating POA-Derived Interneurons Fated for the Murine Cerebral Cortex
Published in Cerebral cortex (New York, N.Y. 1991) (01-12-2017)“…The proliferative niches in the subpallium generate a rich cellular variety fated for diverse telencephalic regions. The embryonic preoptic area (POA)…”
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A single-cell strategy for the identification of intronic variants related to mis-splicing in pancreatic cancer
Published in NAR genomics and bioinformatics (01-06-2024)“…Abstract Most clinical diagnostic and genomic research setups focus almost exclusively on coding regions and essential splice sites, thereby overlooking other…”
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Neuroblastoma Progression Correlates with Downregulation of the Lymphangiogenesis Inhibitor sVEGFR-2
Published in Clinical cancer research (01-03-2010)“…Tumor progression correlates with the induction of a dense supply of blood vessels and the formation of peritumoral lymphatics. Hemangiogenesis and…”
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Neuroblastoma progression correlates with down-regulation of the lymphangiogenesis inhibitor sVEGFR-2
Published in Clinical cancer research (23-02-2010)Get full text
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mRNA Profiling Reveals Determinants of Trastuzumab Efficiency in HER2-Positive Breast Cancer: e0117818
Published in PloS one (01-02-2015)“…Intrinsic and acquired resistance to the monoclonal antibody drug trastuzumab is a major problem in the treatment of HER2-positive breast cancer. A deeper…”
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