Search Results - "Luderer, J"

Radioprotection by Hymenialdisine-Derived Checkpoint Kinase 2 Inhibitors by Nguyen, Thu N. T., Saleem, Rahman S. Z., Luderer, Micah J., Hovde, Stacy, Henry, R. William, Tepe, Jetze J.

“…DNA damage induced by ionizing radiation activates the ataxia telangiectasia mutated pathway, resulting in apoptosis or DNA repair. The serine/threonine…”
Get full text

Enhancing proteasome-inhibitory activity and specificity of bortezomib by CD38 targeted nanoparticles in multiple myeloma by de la Puente, Pilar, Luderer, Micah J., Federico, Cinzia, Jin, Abbey, Gilson, Rebecca C., Egbulefu, Christopher, Alhallak, Kinan, Shah, Shruti, Muz, Barbara, Sun, Jennifer, King, Justin, Kohnen, Daniel, Salama, Noha Nabil, Achilefu, Samuel, Vij, Ravi, Azab, Abdel Kareem

“…The establishment of more effective treatments that can circumvent chemoresistance in Multiple Myeloma (MM) is a priority. Although bortezomib (BTZ) is one of…”
Get full text

Safety and risk/benefit analysis of ibutilide for acute conversion of atrial fibrillation/flutter by KOWEY, P. R, VANDERLUGT, J. T, LUDERER, J. R

“…Safety data were reviewed from several controlled clinical trials of ibutilide, a new class III antiarrhythmic drug recently approved for the acute…”
Get full text

A survey on psychiatric patients’ use of non-medical alternative practitioners: incidence, methods, estimation, and satisfaction by Demling, J.H., Neubauer, S, Luderer, H.-J, Wörthmüller, M

“…Objectives: We investigated to what extent psychiatric inpatients consult Heilpraktiker, i.e. non-academically trained providers of complementary and…”
Get full text

Clinicians' information habits, patients' knowledge of diagnoses and etiological concepts in four different clinical samples by Luderer, H J, Böcker, F M

“…A total of 230 psychiatric inpatients and their physicians in charge took part in semistandardized interviews. Patients suffering from schizophrenia received…”
Get more information

The haemodynamic effects and pharmacokinetics of intravenous nicorandil in healthy volunteers by WOLF, D. L, FERRY, J, HEARRON, A. E, FROESCHKE, M. O, LUDERER, J. R

“…We have studied the effects of intravenous nicorandil, a mixed arterial and venous vasodilator, in 48 healthy volunteers. Nicorandil (20, 28, 39, 54, 74, 103,…”
Get full text

The pharmacokinetics and haemodynamic effects of continuous nicorandil infusion in healthy volunteers by WOLF, D. L, HEARRON, A. E, METZLER, C. M, FERRY, J. J, FROESCHKE, M. O, LUDERER, J. R

“…We have studied the pharmacokinetics and haemodynamic effects of nicorandil after a 12-h infusion. Nicorandil is a mixed vasodilator combining the actions of a…”
Get full text

Rapid extraction of arachidonic acid metabolites utilizing octadecyl reversed-phase columns by Luderer, J R, Riley, D L, Demers, L M

Get more information

Clinical pharmacology and first-time-in-man studies: the FDA levels the playing field by Luderer, J, Piergies, A A, Jorkasky, D, Sedman, A, Reele, S, Froehlich, J, Cavanaugh, J, Steinman, G L

Get more information

Pharmacokinetics and cyclooxygenase inhibition of itazigrel in normal volunteers after single oral doses by Hsyu, P H, Koets, M D, Luderer, J R

“…The pharmacokinetics and cyclooxygenase inhibition of itazigrel were studied in normal male volunteers. In a low-dose study, subjects received a single oral…”
Get more information

Familial essential thrombocythemia by Eyster, M E, Saletan, S L, Rabellino, E M, Karanas, A, McDonald, T P, Locke, L A, Luderer, J R

“…Primary or essential thrombocythemia is rarely observed in childhood, and familial occurrence has been reported only once. In this study, essential…”
Get more information

Continuous intravenous dosing with ciprostene using a portable pump in ambulatory patients by Wolf, D L, Metzler, C M, Froeschke, M O, Luderer, J R

“…Parenteral compounds present special drug delivery challenges. This open-label study evaluated a portable infusion pump as a means to deliver intravenous…”
Get more information

Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain by Arnold, J M, Kowey, P R, Wolf, D L, Jungbluth, G L, Hearron, A E, Luderer, J R

“…We studied the acute haemodynamic dose response of nicorandil, a combined nitrate and potassium channel opener, in patients evaluated for chest pain. Single…”
Get more information

Acute effects of increasing doses of nicorandil on renal function in man by Wolf, D L, Jungbluth, G L, Metzler, C M, Froeschke, M O, DeLoof, M J, Luderer, J R

“…The effects of nicorandil, a nicotinamide derived vasodilator combining nitrate and potassium channel opener actions, on kidney function have not been…”
Get more information

Flicker Fusion Frequency and Organic Syndrome in Alcoholics by Pillunat, L. E., Christ, Th, Luderer, H.-J., Stodtmeister, R.

“…Flicker fusion frequencies of 48 healthy controls and of 35 alcoholics were measured to detect possible associations between flicker fusion and signs of…”
Get full text

Age and ceftriaxone kinetics by Luderer, J R, Patel, I H, Durkin, J, Schneck, D W

“…One gram ceftriaxone was injected at a constant rate in an intravenous infusion over 30 min to eight elderly subjects (mean age, 70.5 yr) and eight young…”
Get more information

Effects of nadolol and propranolol on plasma lidocaine clearance by Schneck, D W, Luderer, J R, Davis, D, Vary, J

“…Nadolol and propranolol effects on lidocaine elimination were followed in six healthy men and women. Each received three separate 30-hr infusions of lidocaine…”
Get more information

Plasma prostaglandins in hypercalcemic patients with neoplastic disease by Demers, L M, Allegra, J C, Harvey, H A, Lipton, A, Luderer, J R, Mortel, R, Brenner, D E

“…Peripheral plasma prostaglandin E (PGE) determinations were performed on a series of 79 patients with solid tumor neoplasms and correlated with their serum…”
Get more information

Rational use of drug levels by Sloan, R W, Luderer, J R

“…Considerable strides have been made in pharmacokinetics the last decade. Such techniques as gas chromatography and radioimmunoassay can measure minute…”
Get more information

The effect of chlorpropamide hyponatremia on mental status in a nursing home population by Sloan, R W, Kreider, R M, Luderer, J R

“…Fifty-nine nursing home patients (average age, 79.9 +/- .9 years) receiving chlorpropamide were screened with a serum sodium determination. Nine patients (15.3…”
Get more information