Search Results - "Luczynski, Maciej T."

Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining by Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Rieger, Simone, Moquet, Jayne, Spanswick, Victoria J., Hartley, John A., Rothkamm, Kai, Huang, Paul H., Mittnacht, Sibylle

“…Deficiencies in DNA double-strand break (DSB) repair lead to genetic instability, a recognized cause of cancer initiation and evolution. We report that the…”
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Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants by Iwai, Leo K, Payne, Leo S, Luczynski, Maciej T, Chang, Francis, Xu, Huifang, Clinton, Ryan W, Paul, Angela, Esposito, Edward A, Gridley, Scott, Leitinger, Birgit, Naegle, Kristen M, Huang, Paul H

“…Collagen is an important extracellular matrix component that directs many fundamental cellular processes including differentiation, proliferation and motility…”
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Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors by Wong, Jocelyn P., Todd, Jason R., Finetti, Martina A., McCarthy, Frank, Broncel, Malgorzata, Vyse, Simon, Luczynski, Maciej T., Crosier, Stephen, Ryall, Karen A., Holmes, Kate, Payne, Leo S., Daley, Frances, Wai, Patty, Jenks, Andrew, Tanos, Barbara, Tan, Aik-Choon, Natrajan, Rachael C., Williamson, Daniel, Huang, Paul H.

“…Subunits of the SWI/SNF chromatin remodeling complex are mutated in a significant proportion of human cancers. Malignant rhabdoid tumors (MRTs) are lethal…”
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Discoidin domain receptors: a proteomic portrait by Iwai, Leo K, Luczynski, Maciej T, Huang, Paul H

“…The discoidin domain receptors (DDRs) are collagen-binding receptor tyrosine kinases that have been implicated in a number of fundamental biological processes…”
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Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity by Luczynski, Maciej T., Harrison, Peter T., Lima, Nadia, Krasny, Lukas, Paul, Angela, Huang, Paul H.

“…Discoidin Domain Receptor 2 (DDR2) is a collagen-binding receptor tyrosine kinase that initiates delayed and sustained tyrosine phosphorylation signalling. To…”
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Corrigendum to “Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity” [Biochem. Biophys. Res. Commun. 501 (1) (18 June 2018) 124–130] by Luczynski, Maciej T., Harrison, Peter T., Lima, Nadia, Krasny, Lukas, Paul, Angela, Huang, Paul H.

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Retinoblastoma family proteins: New players in DNA repair by non-homologous end-joining by Huang, Paul H., Cook, Rebecca, Zoumpoulidou, Georgia, Luczynski, Maciej T., Mittnacht, Sibylle

“…Loss of retinoblastoma protein (RB1) function is a major driver in cancer development. We have recently reported that, in addition to its well-documented…”
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