Search Results - "Luckow, Bruno"

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways by Kierdorf, Katrin, Erny, Daniel, Goldmann, Tobias, Sander, Victor, Schulz, Christian, Perdiguero, Elisa Gomez, Wieghofer, Peter, Heinrich, Annette, Riemke, Pia, Hölscher, Christoph, Müller, Dominik N, Luckow, Bruno, Brocker, Thomas, Debowski, Katharina, Fritz, Günter, Opdenakker, Ghislain, Diefenbach, Andreas, Biber, Knut, Heikenwalder, Mathias, Geissmann, Frederic, Rosenbauer, Frank, Prinz, Marco

“…This study describes the transcriptional programming of yolk sac–derived microglia specification in the brain, in which c-kit–positive erythromyeloid cells are…”
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A simplified method for bronchoalveolar lavage in mice by orotracheal intubation avoiding tracheotomy by Luckow, Bruno, Lehmann, Michael H

“…Bronchoalveolar lavage (BAL) represents an important method to sample immune cells and soluble substances from the lungs of humans and animals suffering from…”
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CCL2 Is a Vascular Permeability Factor Inducing CCR2-Dependent Endothelial Retraction during Lung Metastasis by Roblek, Marko, Protsyuk, Darya, Becker, Paul F, Stefanescu, Cristina, Gorzelanny, Christian, Glaus Garzon, Jesus F, Knopfova, Lucia, Heikenwalder, Mathias, Luckow, Bruno, Schneider, Stefan W, Borsig, Lubor

“…Increased levels of the chemokine CCL2 in cancer patients are associated with poor prognosis. Experimental evidence suggests that CCL2 correlates with…”
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Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency by Porubsky, Stefan, Speak, Anneliese O, Luckow, Bruno, Cerundolo, Vincenzo, Platt, Frances M, Gröne, Hermann-Josef

“…CD1d-restricted natural killer T (NKT) cells, expressing the invariant T cell antigen receptor (TCR) chain encoded by Vα14-Jα18 gene segments in mice and…”
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C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms by Reichel, Christoph A., Puhr-Westerheide, Daniel, Zuchtriegel, Gabriele, Uhl, Bernd, Berberich, Nina, Zahler, Stefan, Wymann, Matthias P., Luckow, Bruno, Krombach, Fritz

“…Initial observations suggested that C-C motif chemokines exclusively mediate chemotaxis of mononuclear cells. In addition, recent studies also implicated these…”
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Chemokine receptors Ccr1, Ccr2, and Ccr5 mediate neutrophil migration to postischemic tissue by Reichel, Christoph A., Khandoga, Andrej, Anders, Hans‐Joachim, Schlöndorff, Detlef, Luckow, Bruno, Krombach, Fritz

“…Leukocyte infiltration of reerfused tissue is a key event in the pathogenesis of ischemia‐reperfusion. However, the role of chemokine receptors Ccr1, Ccr2, and…”
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Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice by Mack, Matthias, Cihak, Josef, Simonis, Christopher, Luckow, Bruno, Proudfoot, Amanda E. I, Bruhl, Hilke, Frink, Michael, Anders, Hans-Joachim, Vielhauer, Volker, Pfirstinger, Jochen, Stangassinger, Manfred, Schlondorff, Detlef

“…The chemokine receptors CCR2 and CCR5 play important roles in the recruitment of monocytes/macrophages and T cells. To better understand the role of both…”
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Chemokine receptor Ccr5 deficiency induces alternative macrophage activation and improves long-term renal allograft outcome by Dehmel, Stefan, Wang, Shijun, Schmidt, Claudia, Kiss, Eva, Loewe, Robert P, Chilla, Silvia, Schlöndorff, Detlef, Gröne, Hermann-Josef, Luckow, Bruno

“…The chemokine (C-C motif) receptor 5 (CCR5) has been implicated in experimental and clinical allograft rejection. To dissect the function of CCR5 in acute and…”
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Chemokine expression precedes inflammatory cell infiltration and chemokine receptor and cytokine expression during the initiation of murine lupus nephritis by PEREZ DE LEMA, Guillermo, MAIER, Holger, NIETO, Elena, VIELHAUER, Volker, LUCKOW, Bruno, MAMPASO, Francisco, SCHLÖNDORFF, Detlef

“…Lupus nephritis is characterized by immune complex deposition and inflammatory cell infiltration. Therefore, the initiation and progression of lupus nephritis…”
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CC chemokine receptor 5 and renal-transplant survival by Fischereder, Michael, Luckow, Bruno, Hocher, Berthold, Wüthrich, Rudolf P, Rothenpieler, Uwe, Schneeberger, Helmut, Panzer, Ulf, Stahl, Rolf AK, Hauser, Ingeborg A, Budde, Klemens, Neumayer, Hans-H, Krämer, Bernhard K, Land, Walter, Schlöndorff, Detlef

“…About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5) with a 32 bp deletion (CCR5Δ32), which…”
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Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity by Mack, M, Luckow, B, Nelson, P J, Cihak, J, Simmons, G, Clapham, P R, Signoret, N, Marsh, M, Stangassinger, M, Borlat, F, Wells, T N, Schlöndorff, D, Proudfoot, A E

“…CCR5, a chemokine receptor expressed on T cells and macrophages, is the principal coreceptor for M-tropic HIV-1 strains. Recently, we described an NH2-terminal…”
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Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease by De Lema, Guillermo Pérez, Lucio-Cazaña, Francisco Javier, Molina, A.N.A., Luckow, Bruno, Schmid, Holger, de Wit, Cor, Moreno-Manzano, Victoria, Banas, Bernhard, Mampaso, Francisco, Schlöndorff, Detlef

“…Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease. Retinoic acid (tRA) is an active metabolite of vitamin A with…”
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Transcriptional regulation of the interleukin-6 gene in mesangial cells by GRASSL, C, LUCKOW, B, SCHLONDORFF, D, DENDORFER, U

“…Cytokine secretion by mesangial cells (MC) plays a major role in the pathogenesis of glomerulonephritis. To define signaling events that occur during the…”
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Chemokine and chemokine receptor expression during initiation and resolution of immune complex glomerulonephritis by ANDERS, Hans-Joachim, VIELHAUER, Volker, KRETZLER, Matthias, COHEN, Clemens D, SEGERER, Stephan, LUCKOW, Bruno, WELLER, Lars, GRÖNE, Hermann-Josef, SCHLÖNDORFF, Detlef

“…Chemokines participate in leukocyte infiltration, which plays a major role in glomerular injury during immune complex glomerulonephritis (IC-GN). Because…”
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Chemokine and chemokine receptor expression in a novel human mesangial cell line by BANAS, B, LUCKOW, B, SCHLÖNDORFF, D, MÖLLER, M, KLIER, C, NELSON, P. J, SCHADDE, E, BRIGL, M, HALEVY, D, HOLTHÖFER, H, REINHART, B

“…Chemokines are thought to play a pivotal role in mediating the selective migration of leukocytes into sites of tissue injury. The local production of…”
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Angiotensin inhibition reduces glomerular damage and renal chemokine expression in MRL/lpr mice by Pérez De Lema, Guillermo, De Wit, Cor, Cohen, Clemens D, Nieto, Elena, Molina, Ana, Banas, Bernhard, Luckow, Bruno, Vicente, Ana B, Mampaso, Francisco, Schlöndorff, Detlef

“…Beneficial effects of angiotensin II inhibition during inflammatory renal disease may involve both hemodynamic and nonhemodynamic mechanisms. To analyze…”
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The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution by Kaestner, K H, Hiemisch, H, Luckow, B, Schütz, G

“…The rat HNF-3 (hepatocyte nuclear factor 3) gene family encodes three transcription factors known to be important in the regulation of gene expression in liver…”
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Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5‐deficient mice by Luckow, Bruno, Joergensen, Joanne, Chilla, Silvia, Li, Jian‐Ping, Henger, Anna, Kiss, Eva, Wieczorek, Grazyna, Roth, Lukas, Hartmann, Nicole, Hoffmann, Reinhard, Kretzler, Matthias, Nelson, Peter J., de Lema, Guillermo Pérez, Maier, Holger, Wurst, Wolfgang, Balling, Rudi, Pfeffer, Klaus, Gröne, Hermann‐Josef, Schlöndorff, Detlef, Zerwes, Hans‐Günter

“…Experimental and human organ transplant studies suggest an important role for chemokine (C‐C‐motif) receptor‐5 (CCR5) in the development of acute and chronic…”
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C–C chemokine receptor type 2 mediates glomerular injury and interstitial fibrosis in focal segmental glomerulosclerosis by Wilkening, Anja, Krappe, Julia, Mühe, Anne M, Lindenmeyer, Maja T, Eltrich, Nuru, Luckow, Bruno, Vielhauer, Volker

“…Abstract Background Glomerulosclerosis and tubulointerstitial fibrosis are hallmarks of chronic kidney injury leading to end-stage renal disease. Inflammatory…”
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Phenotyping renal leukocyte subsets by four-color flow cytometry: characterization of chemokine receptor expression by Vielhauer, Volker, Anders, Hans-Joachim, Pérez de Lema, Guillermo, Luckow, Bruno, Schlöndorff, Detlef, Mack, Matthias

“…To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal…”
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