Search Results - "Luciola Zanette, Dalila"
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Essential properties and pitfalls of colorimetric Reverse Transcription Loop-mediated Isothermal Amplification as a point-of-care test for SARS-CoV-2 diagnosis
Published in Molecular medicine (Cambridge, Mass.) (26-03-2021)“…SARS-CoV-2 Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) colorimetric detection is a sensitive and specific point-of-care molecular…”
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2
Cancer/Testis Antigen Expression on Mesenchymal Stem Cells Isolated from Different Tissues
Published in Anticancer research (01-12-2010)“…The expression of cancer/testis antigens (CTAs) on additional normal tissues or stem cells may restrict their use as cancer targets. The objective of the…”
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3
Development and evaluation of a lyophilization protocol for colorimetric RT-LAMP diagnostic assay for COVID-19
Published in Scientific reports (09-05-2024)“…Molecular diagnostics involving nucleic acids (DNA and RNA) are regarded as extremely functional tools. During the 2020 global health crisis, efforts…”
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4
Fluorescent and colorimetric RT-LAMP as a rapid and specific qualitative method for chronic myeloid leukemia diagnosis
Published in Analytical biochemistry (15-03-2022)“…The detection of BCR-ABL1 mRNA transcripts is essential to molecular chronic myeloid leukemia (CML) diagnosis. In most cases, the RT-qPCR technique is…”
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Plasma Exosome-Derived microRNAs as Potential Diagnostic and Prognostic Biomarkers in Brazilian Pancreatic Cancer Patients
Published in Biomolecules (Basel, Switzerland) (31-05-2022)“…Pancreatic cancer represents one of the leading causes of oncological death worldwide. A combination of pancreatic cancer aggressiveness and late diagnosis are…”
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6
The Screening of microRNAs in Chronic Myeloid Leukemia: A Clinical Evaluation
Published in International journal of molecular sciences (01-03-2024)“…Chronic myeloid leukemia (CML) is a type of leukemia whose main genetic marker is the reciprocal translocation that leads to the production of the oncoprotein…”
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7
Lyophilization of Molecular Biology Reactions: A Review
Published in Mini reviews in medicinal chemistry (01-01-2023)“…Molecular biology is a widely used and widespread technique in research and as a laboratory diagnostic tool, aiming to investigate targets of interest from the…”
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Screening of Exosome-Derived Proteins and Their Potential as Biomarkers in Diagnostic and Prognostic for Pancreatic Cancer
Published in International journal of molecular sciences (01-08-2023)“…In the oncological area, pancreatic cancer is one of the most lethal diseases, with 5-year survival rising just 10% in high-development countries. This disease…”
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9
Molecular BCR::ABL1 Quantification and ABL1 Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study
Published in International journal of molecular sciences (14-06-2023)“…Chronic myeloid leukemia (CML) is a well-characterized oncological disease in which virtually all patients possess a translocation (9;22) that generates the…”
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10
Expression of HOTAIR and PTGS2 as potential biomarkers in chronic myeloid leukemia patients in Brazil
Published in Frontiers in oncology (10-10-2024)“…Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm in which all the patients has the translocation ( ) that generates de BCR::ABL1 tyrosine…”
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11
Urinary mRNA-based biomarkers for non-muscle-invasive bladder cancer: a mini-review
Published in Frontiers in oncology (09-08-2024)“…Bladder cancer (BC) is the second most common type of cancer of the urinary system. Approximately 75% of the cases are non-muscle invasive bladder cancer…”
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12
Placenta-Enriched LincRNAs MIR503HG and LINC00629 Decrease Migration and Invasion Potential of JEG-3 Cell Line
Published in PloS one (29-03-2016)“…LINC00629 and MIR503HG are long intergenic non-coding RNAs (lincRNAs) mapped on chromosome X (Xq26), a region enriched for genes associated with human…”
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13
Circulating Cell-Free Nucleic Acids as Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer
Published in Biomedicines (01-04-2023)“…A lack of reliable early diagnostic tools represents a major challenge in the management of pancreatic cancer (PCa), as the disease is often only identified…”
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14
Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin
Published in Frontiers in immunology (17-07-2020)“…The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation,…”
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Obesity as a Possible Risk Factor for Progression from Monoclonal Gammopathy of Undetermined Significance Progression into Multiple Myeloma: Could Myeloma Be Prevented with Metformin Treatment?
Published in Advances in hematology (2021)“…Obesity is increasingly associated with the transformation of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma (MM). Obesity,…”
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16
Simvastatin modulates mesenchymal stromal cell proliferation and gene expression
Published in PloS one (13-04-2015)“…Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway, responsible for the biosysnthesis of cholesterol. However, statins also…”
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17
Expression signatures of DNA repair genes correlate with survival prognosis of astrocytoma patients
Published in Tumor biology (01-04-2017)“…Astrocytomas are the most common primary brain tumors. They are very resistant to therapies and usually progress rapidly to high-grade lesions. Here, we…”
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Beneficial Bacteria in the Gut Microbiota May Lead to Improved Metabolic and Immunological Status in Chronic Obstructive Pulmonary Disease
Published in Medical sciences (Basel) (01-09-2024)“…The progression of chronic obstructive pulmonary disease (COPD) is characterized by functional changes in the airways. The lung-gut axis and gut microbiota…”
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Association of laboratory markers and cerebral blood flow among sickle cell anemia children
Published in Frontiers in pediatrics (26-08-2022)“…BackgroundStroke is one of the highest complications of sickle-cell anemia (SCA). The Transcranial Doppler (TCD) has been adopted worldwide as a gold standard…”
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20
Metagenomic insights into the plasma virome of Brazilian patients with prostate cancer
Published in Molecular & cellular oncology (2023)“…Growing evidence suggests that metavirome changes could be associated increased risk for malignant cell transformation. Considering Viruses have been proposed…”
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