Search Results - "Luciani, MG"

p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products by Fåhraeus, Robin, Yin, Yili, Stephen, Charles W, Luciani, M. Gloria

“…Activation of the p53 tumour suppressor protein can lead to cell-cycle arrest or apoptosis. p53 function is controlled by the mdm2 oncogene product, which…”
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INFECTION, INFLAMMATION, AND GASTROINTESTINAL CANCER by Boland, C R, Luciani, M G, Gasche, C, Goel, A

“…[...]most laboratory models have been carefully developed to match the carcinogen with the host. [...]a virus carried by most healthy individuals has been…”
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ΔN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53 by COURTOIS, Stéphanie, VERHAEGH, Gerald, NORTH, Sophie, LUCIANI, Maria-Gloria, LASSUS, Patrice, HIBNER, Ula, OREN, Moshe, HAINAUT, Pierre

“…The tumor suppressor protein p53 is ubiquitously expressed as a major isoform of 53 kD, but several forms of lower molecular weight have been observed. Here,…”
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P5-05-04: Bipshenol-A Modulates Estrogen Receptor Alpha and Compromises Tamoxifen-Induced Apoptosis by Goodson, III WH, Luciani, MG, Sayeed, A, Jaffee, I, Moore, II DH, Dairkee, SH

“…Abstract BACKGROUND: Antiestrogens are important for treatment and prevention of breast cancer. Such drugs influence multiple pathways involved in regulation…”
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Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2 by Pospísilová, Sárka, Brázda, Václav, Kucharíková, Katerina, Luciani, M Gloria, Hupp, Ted R, Skládal, Petr, Palecek, Emil, Vojtesek, Borivoj

“…p53 is one of the most important regulators of cell proliferation and differentiation and of programmed cell death, triggering growth arrest and/or apoptosis…”
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The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A by Luciani, M.Gloria, Hutchins, James R.A, Zheleva, Daniella, Hupp, Ted R

“…Radiation injury to cells enhances C-terminal phosphorylation of p53 at both Ser315 and Ser392 in vivo, suggesting the existence of two cooperating DNA…”
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The development of a CDK2-docking site peptide that inhibits p53 and sensitizes cells to death by Ferguson, Michelle, Luciani, M Gloria, Finlan, Lee, Rankin, Elaine M, Ibbotson, Sally, Fersht, Alan, Hupp, Tedd R

“…Cyclin-dependent protein kinases play important roles in cell cycle progression and are attractive targets for the design of anti-proliferative drugs. Two…”
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A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication by Jares, Pedro, Luciani, M Gloria, Blow, J Julian

“…Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin…”
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The monocyte chemotactic protein 1 (MCP-1) and interleukin 8 (IL-8) in Hodgkin's disease and in solid tumours by LUCIANI, M. G, STOPPACCIARO, A, PERI, G, MANTOVANI, A, RUCO, L. P

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