Search Results - "Luciani, M. Gloria"

Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress by Woodward, Anna M, Göhler, Thomas, Luciani, M. Gloria, Oehlmann, Maren, Ge, Xinquan, Gartner, Anton, Jackson, Dean A, Blow, J. Julian

“…In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2-7 (Mcm2-7)…”
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Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM by Luciani, M.Gloria, Campregher, Christoph, Gasche, Christoph

“…Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Most of the clinical data on CRC prevention have come from the use of aspirin. Besides…”
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p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products by Fåhraeus, Robin, Yin, Yili, Stephen, Charles W, Luciani, M. Gloria

“…Activation of the p53 tumour suppressor protein can lead to cell-cycle arrest or apoptosis. p53 function is controlled by the mdm2 oncogene product, which…”
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5-ASA Affects Cell Cycle Progression in Colorectal Cells by Reversibly Activating a Replication Checkpoint by Luciani, M. Gloria, Campregher, Christoph, Fortune, John M, Kunkel, Thomas A, Gasche, Christoph

“…Background & Aims: Individuals with inflammatory bowel disease are at risk of developing colorectal cancer (CRC). Epidemiologic, animal, and laboratory studies…”
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Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects by Dairkee, Shanaz H., Moore, Dan H., Luciani, M. Gloria, Anderle, Nicole, Gerona, Roy, Ky, Karina, Torres, Samantha M., Marshall, Polly V., Goodson III, William H.

“…Estrogenic overstimulation is carcinogenic to the human breast. Personal care products (PCPs) commonly contain xenoestrogens (XE), such as parabens and…”
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Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus by Luciani, M Gloria, Oehlmann, Maren, Blow, J Julian

“…In most eukaryotes, replication origins fire asynchronously throughout S-phase according to a precise timing programme. When replication fork progression is…”
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Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells by Dairkee, Shanaz H, Luciani-Torres, M Gloria, Moore, Dan H, Goodson, 3rd, William H

“…Widespread distribution of bisphenol-A (BPA) complicates epidemiological studies of possible carcinogenic effects on the breast because there are few unexposed…”
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Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2 by Pospísilová, Sárka, Brázda, Václav, Kucharíková, Katerina, Luciani, M Gloria, Hupp, Ted R, Skládal, Petr, Palecek, Emil, Vojtesek, Borivoj

“…p53 is one of the most important regulators of cell proliferation and differentiation and of programmed cell death, triggering growth arrest and/or apoptosis…”
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The development of a CDK2-docking site peptide that inhibits p53 and sensitizes cells to death by Ferguson, Michelle, Luciani, M Gloria, Finlan, Lee, Rankin, Elaine M, Ibbotson, Sally, Fersht, Alan, Hupp, Tedd R

“…Cyclin-dependent protein kinases play important roles in cell cycle progression and are attractive targets for the design of anti-proliferative drugs. Two…”
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A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication by Jares, Pedro, Luciani, M Gloria, Blow, J Julian

“…Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin…”
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Stoichiometric Phosphorylation of Human p53 at Ser315Stimulates p53-dependent Transcription by Blaydes, Jeremy P., Luciani, M. Gloria, Pospisilova, Sarka, Ball, Helen Mei-Ling, Vojtesek, Borek, Hupp, Ted R.

“…p53 protein activity as a transcription factor can be activated in vivo by antibodies that target its C-terminal negative regulatory domain suggesting that…”
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Reply by Luciani, M. Gloria, Gasche, Christoph

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Reply by Luciani, M. Gloria, Gasche, Christoph

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Excess Mcm2-7 license dormant origins d replication that can be used under conditions of replicative stress by Woodward, Anna M, Göhler, Thomas, Luciani, M Gloria, Oehlmann, Maren

“…In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2-7 (Mcm2-7)…”
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Inhibition of PAK-1 by Mesalazine Increases Cell Adhesion in Colorectal Cancer Cells by Khare, Vineeta, Lyakhovich, Alex, Lang, Michaela, Tichy, Boris, Pospisilova, Sarka, Luciani-Torres, M Gloria, Gasche, Christoph

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The Development of a CDK2-Docking Site Peptide that Inhibits p53 and Sensitizes Cells to Death by Ferguson, Michelle, Luciani, M.Gloria, Finlan, Lee, Ibbotson, Sally, Fersht, Alan, Hupp, Ted R.

“…Cyclin-dependent protein kinases play important roles in cell cycle progression and are attractive targets for the design of anti-proliferative drugs. Two…”
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