Search Results - "Luciani, M"
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Accuracy and reliability of tele‐ultrasonography in detecting gastrointestinal obstruction in dogs and cats
Published in Journal of small animal practice (01-06-2023)“…Objectives To assess the accuracy and interobserver agreement of tele‐ultrasonography for the diagnosis of gastrointestinal obstruction in small animals by…”
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Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells
Published in Carcinogenesis (New York) (01-03-2013)“…Widespread distribution of bisphenol-A (BPA) complicates epidemiological studies of possible carcinogenic effects on the breast because there are few unexposed…”
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Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress
Published in The Journal of cell biology (05-06-2006)“…In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2-7 (Mcm2-7)…”
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Reduction of daily-use parabens and phthalates reverses accumulation of cancer-associated phenotypes within disease-free breast tissue of study subjects
Published in Chemosphere (Oxford) (01-05-2023)“…Estrogenic overstimulation is carcinogenic to the human breast. Personal care products (PCPs) commonly contain xenoestrogens (XE), such as parabens and…”
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p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products
Published in Nature cell biology (01-06-2002)“…Activation of the p53 tumour suppressor protein can lead to cell-cycle arrest or apoptosis. p53 function is controlled by the mdm2 oncogene product, which…”
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The epilepsy specialist nurse: A mixed-methods case study on the role and activities
Published in Seizure (London, England) (01-02-2021)“…•Groups of Epilepsy Specialist Nurses can efficaciously function in a hospital.•The Epilepsy Specialist Nurse offers holistic care to patients and their…”
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Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells
Published in Gut (01-06-2008)“…Chronic inflammation in ulcerative colitis is associated with increased risk for colorectal cancer. Its molecular pathway of cancer development is poorly…”
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Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
Published in Nature communications (29-03-2019)“…In embryonic stem cells, promoters of key lineage-specific differentiation genes are found in a bivalent state, having both activating H3K4me3 and repressive…”
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Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM
Published in Carcinogenesis (New York) (01-10-2007)“…Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Most of the clinical data on CRC prevention have come from the use of aspirin. Besides…”
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PRMT5 regulates ATF4 transcript splicing and oxidative stress response
Published in Redox biology (01-05-2022)“…Protein methyltransferase 5 (PRMT5) symmetrically dimethylates arginine residues leading to regulation of transcription and splicing programs. Although PRMT5…”
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Phase IIa study of dabigatran etexilate in children with venous thrombosis: pharmacokinetics, safety, and tolerability
Published in Journal of thrombosis and haemostasis (01-11-2017)“…Essentials Dabigatran etexilate may provide a new treatment option for pediatric venous thromboembolism. Children aged 1 to < 12 years were given dabigatran…”
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Discovery of a chemical probe for PRDM9
Published in Nature communications (17-12-2019)“…PRDM9 is a PR domain containing protein which trimethylates histone 3 on lysine 4 and 36. Its normal expression is restricted to germ cells and attenuation of…”
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Psychological impairments burden and spirituality in caregivers of terminally ill cancer patients
Published in European journal of cancer care (01-01-2018)“…The role of spirituality on the psychological health was mostly investigated through studies conducted in terminally ill patients. However, there are not…”
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The novel nematicide wact-86 interacts with aldicarb to kill nematodes
Published in PLoS neglected tropical diseases (05-04-2017)“…Parasitic nematodes negatively impact human and animal health worldwide. The market withdrawal of nematicidal agents due to unfavourable toxicities has limited…”
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Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation
Published in Cancer cell (12-08-2019)“…Cancer-associated mutations in genes encoding RNA splicing factors (SFs) commonly occur in leukemias, as well as in a variety of solid tumors, and confer…”
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Long-COVID Headache
Published in SN comprehensive clinical medicine (2021)“…The so-called long COVID-19 is a set of symptoms that accompanies the patient even for months after discharge from the hospital. These symptoms include easy…”
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Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery
Published in Nature communications (24-07-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1 -deficient mice
Published in Nature genetics (01-02-2000)“…Mutations in the gene encoding ATP-binding cassette transporter 1 ( ABC1) have been reported in Tangier disease (TD), an autosomal recessive disorder that is…”
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Early nucleolar disorganization in Dictyostelium cell death
Published in Cell death & disease (05-01-2017)“…Cell death occurs in all eukaryotes, but it is still not known whether some core steps of the cell death process are conserved. We investigated this using the…”
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