Search Results - "Luciana Nardinelli"

Risk factors and incidence of thrombosis in a Brazilian cohort of patients with Philadelphia-negative myeloproliferative neoplasms by Seguro, Fernanda Salles, Teixeira, Larissa Lane Cardoso, da Rosa, Lidiane Inês, da Silva, Wellington Fernandes, Nardinelli, Luciana, Bendit, Israel, Rocha, Vanderson

“…Few data are available regarding epidemiology and outcomes of Philadelphia-negative chronic myeloproliferative neoplasms (MPN) in Latin America. Therefore,…”
Get full text

Adult acute lymphoblastic leukemia in a resource-constrained setting: outcomes after expansion of genetic evaluation by Silva, Wellington F., Amano, Mariane T., Perruso, Luiza L., Cordeiro, Maria Gabriella, Kishimoto, Renata Kiyomi, de Medeiros Leal, Aline, Nardinelli, Luciana, Bendit, Israel, Velloso, Elvira DRP, Rego, Eduardo M., Rocha, Vanderson

“…Acute lymphoblastic leukemia (ALL) is a challenging disease with a growing genetic landscape, even though there is substantial gap between developed and…”
Get full text

Comparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasms by Didone, Alline, Nardinelli, Luciana, Marchiani, Mariana, Ruiz, Antonio Roberto Lancha, de Lima Costa, Ariel Lais, Lima, Ismael Severino, Santos, Nathalia Moreira, Sanabani, Sabri Saeed, Bendit, Israel

“…A mutation in the JAK2 gene, V617F, has been identified in several BCR-ABL1 negative myeloproliferative neoplasms (MPN): polycythemia vera (PV), essential…”
Get full text

Successful Pregnancy and Delivery in a Patient with Chronic Myeloid Leukemia while on Dasatinib Therapy by Bendit, Israel, Ferreira, Patrícia B., Nardinelli, Luciana, Dorliac-Llacer, Pedro Enrique, Novaes, Mafalda M. Y., Serpa, Mariana, Conchon, Monika, Sanabani, Sabri S.

“…Here we report the case of an 18-year-old woman with chronic myeloid leukemia (CML) who became pregnant while undergoing treatment with dasatinib. Before…”
Get full text

Treatment-Free Response in Chronic Myeloid Leukemia Using Brazilian Imatinib Copies As First Line - Results from Two Prospective Clinical Trials by Centrone, Renato Torrescasana, Seguro, Fernanda S, Bellesso, Marcelo, Nardinelli, Luciana, Bendit, Israel, Rocha, Vanderson, Alves, Adelson

Get full text

Rhoa Mutation Is a Potential Biomarker Associated with Adverse Prognosis and High- Tumor Burden in Patients with Nodal Peripheral Lymphomas with T-Helper Follicular Phenotype (nPTCL-Thf): Data from a Brazilian Retrospective Cohort of Nodal PTCL by Lage, Luis Alberto de Padua Covas, Barreto, Guilherme Carneiro, Culler, Hebert Fabricio, Cavalcanti, Jéssica Billar, Alves, Lucas de Oliveira, Nardinelli, Luciana, Bendit, Israel, Rocha, Vanderson, Pereira, Juliana

“…Introduction: Nodal PTCL constitute a rare group of aggressive malignancies with heterogeneous clinical-biological presentation and outcomes. In the last…”
Get full text

Lymphocyte Subpopulations and Expression of Immune Checkpoint Receptors PD-1 and Tim-3 in Patients with Chronic Myeloid Leukemia in a Discontinuation Trial by Seguro, Fernanda S, Maciel, Felipe VR, Lopes, Guilherme O, Nardinelli, Luciana, Rocha, Vanderson, Bendit, Israel

“…Introduction: Immunological factors have been associated with deep molecular response (DMR) and treatment-free remission (TFR) in chronic myeloid leukemia…”
Get full text

Potency and efficacy of pharmacological PIP4K2 inhibitors in acute lymphoblastic leukemia by Lima, Keli, Nogueira, Frederico Lisboa, Cipelli, Marcella, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego Antonio, da Silva, Wellington Fernandes, Cavaglieri, Rita de Cássia, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Câmara, Niels Olsen Saraiva, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Acute lymphoblastic leukemia (ALL), a complex malignancy, displays varying expression profiles of PIP4K2-related genes in adult patients. While PIP4K2A…”
Get full text

Real-World Data for FLT3-Mutated Acute Myeloid Leukemia Patients Treated in Resource-Constrained Settings by Silva, Wellington F, Mendes, Fernanda Rodrigues, Sartori, Marco, Madeira, Maria Isabel A, Pagnano, Katia B, Gloria, Ana Beatriz F, Nunes, Elenaide C., Nardinelli, Luciana, Medeiros, Rita De Cássia Cavaglieri, Bendit, Israel, Traina, Fabiola, Duarte, Bruno Kosa Lino, Figueiredo-Pontes, Lorena Lobo, Rocha, Vanderson, Velloso, Elvira Deolinda Rodrigues Pereira, Rego, Eduardo Magalhães

“…Background: Fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is a well-established prognostic marker in acute myeloid leukemia (AML), whereas…”
Get full text

Potency and Efficacy of Pharmacological PIP4K2 Inhibitors in Acute Lymphoblastic Leukemia by Lima, Keli, Carvalho, Maria Fernanda Lopes, Pereira-Martins, Diego A., Silva, Wellington F, do Nascimento, Mariane Cristina, de Miranda, Lívia Bassani Lins, Medeiros, Rita de Cássia Cavaglieri, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Schuringa, Jan Jacob, Machado-Neto, João Agostinho, Rego, Eduardo Magalhães

“…Introduction and aims: Adult acute lymphoblastic leukemia (ALL) is a heterogeneous group of highly aggressive hematological malignancies with high recurrence…”
Get full text

Real-world Imatinib Mesylate Treatment in Patients with Chronic Myeloid Leukemia: The Importance of Molecular Monitoring and the Early Molecular Response by Ferreira, Amanda Pifano Soares, Seguro, Fernanda Salles, Abdo, Andre Ramires Neder, Santos, Fernanda Maria, Maciel, Felipe Vieira Rodrigues, Nardinelli, Luciana, Giorgi, Ricardo Rodrigues, Ruiz, Antonio Roberto Lancha, Ferreira, Milton Pifano Soares, Rego, Eduardo Magalhaes, Rocha, Vanderson, Bendit, Israel

“…Introduction Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder characterized by the Philadelphia (Ph) chromosome. After the introduction…”
Get full text

Correction to: Real‑world imatinib mesylate treatment in patients with chronic myeloid leukemia: The importance of molecular monitoring and the early molecular response by Ferreira, Amanda Pifano Soares, Seguro, Fernanda Salles, Abdo, Andre Ramires Neder, Santos, Fernanda Maria, Maciel, Felipe Vieira Rodrigues, Nardinelli, Luciana, Giorgi, Ricardo Rodrigues, Ruiz, Antonio Roberto Lancha, Ferreira, Milton Pifano Soares, Rego, Eduardo Magalhaes, Rocha, Vanderson, Bendit, Israel

Get full text

Clinical, Laboratory, and Genetic Features of Erdheim-Chester Disease Patients from Two Reference Centers in a Developing Country by Guerra Soares Brandão, Antonio Adolfo, Fatobene, Giancarlo, Abdo, Andre, Lage, Luis Alberto de Padua Covas, Bendit, Israel, Nardinelli, Luciana, Coelho de Siqueira, Sheila Aparecida, Levy, Debora, Pereira, Juliana, Rego, Eduardo M, Rocha, Vanderson

“…Erdheim-Chester Disease (ECD) is a rare histiocytic neoplasm with a heterogenous clinical course with asymptomatic localized course or systemic compromise…”
Get full text

Retrospective Comparison between MEC and FLAG-Ida Regimens for Refractory or Relapsed Acute Myeloid Leukemia in Adults by Silva, Wellington F, Da Rosa, Lidiane Inês, Seguro, Fernanda S, Silveira, Douglas R.A., Nardinelli, Luciana, Buccheri, Valeria, Velloso, Elvira DRP, Rocha, Vanderson, Rego, Eduardo M

“…▪ Introduction: There is no consensus regarding the best salvage regimen for refractory or relapsed acute myeloid leukemia (r/rAML), with classic regimens…”
Get full text

MR 4log and low levels of NK cells are associated with higher molecular relapse after imatinib discontinuation: Results of a prospective trial by Seguro, Fernanda S., Maciel, Felipe V.R, Santos, Fernanda M., Abdo, André N.R., Pereira, Thales D.M., Nardinelli, Luciana, Rocha, Vanderson, Bendit, Israel

“…•Therapy-free survival was 54 % after 24 moths of imatinib discontinuation.•MR4 was associated with higher risk of molecular relapse.•NK cells proportion is…”
Get full text

Determination of serum levels of imatinib mesylate in patients with chronic myeloid leukemia: validation and application of a new analytical method to monitor treatment compliance by Rezende, Vinícius Marcondes, Rivellis, Ariane Julio, Gomes, Melissa Medrano, Dörr, Felipe Augusto, Novaes, Mafalda Megumi Yoshinaga, Nardinelli, Luciana, Costa, Ariel Lais de Lima, Chamone, Dalton de Alencar Fisher, Bendit, Israel

“…The goal of this study was to monitor imatinib mesylate therapeutically in the Tumor Biology Laboratory, Department of Hematology and Hemotherapy, Hospital das…”
Get full text

Duration of Major Molecular Response and Discontinuation in Deep Molecular Response (MR4.5) Were Associated with Longer Treatment-Free Survival after Imatinib Discontinuation - Results from Two Prospective Brazilian Trials by Pagnano, Katia B, Seguro, Fernanda S, Miranda, Eliana C, Lopes, Ana Beatriz Pascoal, Abdo, Andre, Delamain, Marcia Torresan, Pereira, Thales, Duarte, Gislaine Borba, Santos, Fernanda Maria, Vianna, Jessica CN, Da Silva, Matheus Sebastian, Nardinelli, Luciana, Povoa, Valquiria, Pavan, Graziele, Vergilio, Bruna R, Rocha, Vanderson, Souza, Carmino Antonio, De Paula, Erich V, Bendit, Israel

“…Several trials have demonstrated the feasibility of discontinuation of tyrosine kinase inhibitors (TKI) treatment in chronic myeloid leukemia (CML) patients…”
Get full text

Combining Clinical Features with Genetic Factors Improves Survival Prediction for Adults with Acute Myeloid Leukemia: Validation of a New Score System in 3 Cohorts by Silveira, Douglas R.A., Quek, Lynn, Corby, Anna, Coelho-Silva, Juan L, Pereira-Martins, Diego A, Vallance, Grant, Brown, Benjamin, Nardinelli, Luciana, Silva, Wellington F, Velloso, Elvira DRP, Traina, Fabiola, Peniket, Andy, Vyas, Paresh, Rego, Eduardo M, Bendit, Israel, Rocha, Vanderson

“…Introduction: Risk stratification in acute myeloid leukemia (AML) is continually being refined as we learn more about the molecular pathophysiology of this…”
Get full text

Clinical significance of Philadelphia‐like‐related genes in a resource‐constrained setting of adult B‐acute lymphoblastic leukemia patients by Lima, Keli, Rojas, César Alexander Ortiz, Nogueira, Frederico Lisboa, da Silva, Wellington Fernandes, Cavaglieri, Rita de Cássia, Nardinelli, Luciana, Leal, Aline de Medeiros, Velloso, Elvira Deolinda Rodrigues Pereira, Bendit, Israel, Alencar, Alvaro, Mullighan, Charles G., Machado‐Neto, João Agostinho, Rego, Eduardo Magalhães

Get full text

E14a2 and e14a2+e13a2 BCR-ABL Transcripts Are Associated with Earlier Cytogenetic and Molecular Response Rates in CML-CP Treated with Imatinib by Pagnano, Katia B, Miranda, Eliana C, Seguro, Fernanda S, Magalhaes, Gustavo HR, Clementino, Nelma D, Moellmann-Coelho, Arthur, Da Silva, Maryanna N, Centrone, Renato, Conchon, Monika, Bortolini, Jaisson, Bortolheiro, Teresa Cristina, Povoa, Valquiria, Nardinelli, Luciana, De Souza, Carmino Antonio, Bendit, Israel

“…Background: The prognostic significance of BCR-ABL1 transcripts in chronic myeloid leukemia (CML) is still controversial. Methods: All consecutive CML patients…”
Get full text