Search Results - "Luciana N. Andrade"
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Alginate Nanoparticles for Drug Delivery and Targeting
Published in Current pharmaceutical design (01-01-2019)“…Nanotechnology refers to the control, manipulation, study and manufacture of structures and devices at the nanometer size range. The small size, customized…”
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(+)-Limonene 1,2-Epoxide-Loaded SLNs: Evaluation of Drug Release, Antioxidant Activity, and Cytotoxicity in an HaCaT Cell Line
Published in International journal of molecular sciences (20-02-2020)“…In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1,2-epoxide and glycerol monostearate (Lim-SLNs), stabilized with…”
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Praziquantel-Solid Lipid Nanoparticles Produced by Supercritical Carbon Dioxide Extraction: Physicochemical Characterization, Release Profile, and Cytotoxicity
Published in Molecules (Basel, Switzerland) (28-10-2019)“…Solid lipid nanoparticles (SLNs) can be produced by various methods, but most of them are difficult to scale up. Supercritical fluid (SCF) is an important tool…”
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Extracellular Vesicle-Packaged miR-195-5p Sensitizes Melanoma to Targeted Therapy with Kinase Inhibitors
Published in Cells (Basel, Switzerland) (05-05-2023)“…Management of advanced melanoma remains challenging, with most BRAF (B-Raf proto-oncogene, serine/threonine kinase)-mutated metastatic patients relapsing…”
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Perillaldehyde 1,2-epoxide loaded SLN-tailored mAb: production, physicochemical characterization and in vitro cytotoxicity profile in MCF-7 cell lines
Published in Pharmaceutics (16-02-2020)“…We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide…”
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Cytotoxic, antitumor and toxicological profile of Passiflora alata leaf extract
Published in Molecules (Basel, Switzerland) (20-10-2020)“…Passiflora alata or passion fruit is a native flowering plant from Amazon, geographically spread from Peru to Brazil. The plant has long been used in folks…”
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Cashew Gum: A Review of Brazilian Patents and Pharmaceutical Applications with a Special Focus on Nanoparticles
Published in Micromachines (Basel) (18-07-2022)“…Natural polysaccharides are structures composed of highly diversified biological macromolecules whose properties have been exploited by a diversity of…”
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In Vitro Characterization, Modelling, and Antioxidant Properties of Polyphenon-60 from Green Tea in Eudragit S100-2 Chitosan Microspheres
Published in Nutrients (31-03-2020)“…Eudragit S100-coated chitosan microspheres (S100Ch) are proposed as a new oral delivery system for green tea polyphenon-60 (PP60). PP60 is a mixture of…”
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β-Cyclodextrin/Isopentyl Caffeate Inclusion Complex: Synthesis, Characterization and Antileishmanial Activity
Published in Molecules (Basel, Switzerland) (12-09-2020)“…Isopentyl caffeate (ICaf) is a bioactive ester widely distributed in nature. Our patented work has shown promising results of this molecule against Leishmania…”
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Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200
Published in PloS one (13-05-2015)“…The aim of this preclinical study was to evaluate the characteristics of the monoclonal antibody Rebmab200, which is a humanized version of the…”
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Anti-tumor efficiency of Perillylalcohol/β-Cyclodextrin inclusion complexes in a sarcoma S180-induced mice model
Published in Pharmaceutics (10-02-2021)“…The low solubility and high volatility of perillyl alcohol (POH) compromise its bioavailability and potential use as chemotherapeutic drug. In this work, we…”
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Antitumor Profile of Combined Matricaria recutita Flower Extract and 5-Fluorouracil Chemotherapy in Sarcoma 180 In Vivo Model
Published in Toxics (Basel) (14-04-2023)“…Medicinal plants have been commonly associated with chemotherapeutic treatments, as an approach to reduce the toxicological risks of classical anticancer…”
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Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy
Published in BMC cancer (13-05-2010)“…Phagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our group suggested that this occurs via Platelet-activating…”
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NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients
Published in NPJ breast cancer (05-04-2019)“…The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number of positive axillary lymph nodes,…”
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Biological Applications of a Chimeric Probe for the Assessment of Galectin-3 Ligands
Published in The journal of histochemistry and cytochemistry (01-10-2007)“…β1–6 branching of N-linked oligosaccharides has been correlated with the progression of different cancers. The leukoagglutinins of Phaseolus vulgaris (L-PHA)…”
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Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors
Published in Journal of controlled release (01-12-2023)“…Cell membrane-derived particles (Mp) are rounded membrane-enclosed particles that are shed from tumor cells. Mp are formed from tumor membranes and are capable…”
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MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells
Published in Journal of pineal research (01-04-2004)“…: Melatonin, a derivative of tryptophan that is present in all vertebrates, was first described in bovine pineal gland. It is known that melatonin is a highly…”
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Corrigendum to “Analysis of the mechanisms of action of isopentyl caffeate against Leishmania”. Biochimie 189 (2021) 158–167
Published in Biochimie (01-10-2022)Get full text
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Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania
Published in Biochimie (01-10-2021)“…Leishmaniasis is a neglected parasitic disease for which the conventional treatment can be considered inefficient and extremely aggressive, generating several…”
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ATR suppresses apoptosis after UVB irradiation by controlling both translesion synthesis and alternative tolerance pathways
Published in Journal of cell science (01-01-2015)“…Ultraviolet (UV) light can stall replication forks owing to the formation of bulky lesions in the DNA. Replication across these blocking lesions occurs through…”
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