Search Results - "Lucia Minoli"

The ER stress response mediator ERO1 triggers cancer metastasis by favoring the angiogenic switch in hypoxic conditions by Varone, Ersilia, Decio, Alessandra, Chernorudskiy, Alexander, Minoli, Lucia, Brunelli, Laura, Ioli, Federica, Piotti, Arianna, Pastorelli, Roberta, Fratelli, Maddalena, Gobbi, Marco, Giavazzi, Raffaella, Zito, Ester

“…Summary Solid tumors are often characterized by a hypoxic microenvironment which contributes, through the hypoxia-inducible factor HIF-1, to the…”
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Antimetastatic and antiangiogenic activity of trabectedin in cutaneous melanoma by Carminati, Laura, Pinessi, Denise, Borsotti, Patrizia, Minoli, Lucia, Giavazzi, Raffaella, D’Incalci, Maurizio, Belotti, Dorina, Taraboletti, Giulia

“…Abstract Trabectedin is a marine-derived antineoplastic drug. Besides targeting the cancer cells, trabectedin has a peculiar activity on the tumor…”
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Selective proliferative response of microglia to alternative polarization signals by Pepe, Giovanna, De Maglie, Marcella, Minoli, Lucia, Villa, Alessandro, Maggi, Adriana, Vegeto, Elisabetta

“…Microglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and…”
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Esmolol during cardiopulmonary resuscitation reduces neurological injury in a porcine model of cardiac arrest by Ruggeri, Laura, Nespoli, Francesca, Ristagno, Giuseppe, Fumagalli, Francesca, Boccardo, Antonio, Olivari, Davide, Affatato, Roberta, Novelli, Deborah, De Giorgio, Daria, Romanelli, Pierpaolo, Minoli, Lucia, Cucino, Alberto, Babini, Giovanni, Staszewsky, Lidia, Zani, Davide, Pravettoni, Davide, Belloli, Angelo, Scanziani, Eugenio, Latini, Roberto, Magliocca, Aurora

“…Primary vasopressor efficacy of epinephrine during cardiopulmonary resuscitation (CPR) is due to its α-adrenergic effects. However, epinephrine plays…”
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Soluble stroma‐related biomarkers of pancreatic cancer by Resovi, Andrea, Bani, Maria Rosa, Porcu, Luca, Anastasia, Alessia, Minoli, Lucia, Allavena, Paola, Cappello, Paola, Novelli, Francesco, Scarpa, Aldo, Morandi, Eugenio, Falanga, Anna, Torri, Valter, Taraboletti, Giulia, Belotti, Dorina, Giavazzi, Raffaella

“…The clinical management of pancreatic ductal adenocarcinoma (PDAC) is hampered by the lack of reliable biomarkers. This study investigated the value of soluble…”
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VEGF pathway inhibition potentiates PARP inhibitor efficacy in ovarian cancer independent of BRCA status by Bizzaro, Francesca, Fuso Nerini, Ilaria, Taylor, Molly A, Anastasia, Alessia, Russo, Massimo, Damia, Giovanna, Guffanti, Federica, Guana, Francesca, Ostano, Paola, Minoli, Lucia, Hattersley, Maureen M, Arnold, Stephanie, Ramos-Montoya, Antonio, Williamson, Stuart C, Galbiati, Alessandro, Urosevic, Jelena, Leo, Elisabetta, Cavallaro, Ugo, Ghilardi, Carmen, Barry, Simon T, Bani, Maria Rosa, Giavazzi, Raffaella

“…Poly ADP-ribose polymerase inhibitors (PARPi) have transformed ovarian cancer (OC) treatment, primarily for tumours deficient in homologous recombination…”
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PEGylated recombinant human hyaluronidase (PEGPH20) pre-treatment improves intra-tumour distribution and efficacy of paclitaxel in preclinical models by Morosi, Lavinia, Meroni, Marina, Ubezio, Paolo, Fuso Nerini, Ilaria, Minoli, Lucia, Porcu, Luca, Panini, Nicolò, Colombo, Marika, Blouw, Barbara, Kang, David W, Davoli, Enrico, Zucchetti, Massimo, D'Incalci, Maurizio, Frapolli, Roberta

“…Scarce drug penetration in solid tumours is one of the possible causes of the limited efficacy of chemotherapy and is related to the altered tumour…”
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Bridging clinic and wildlife care with AI-powered pan-species computational pathology by AbdulJabbar, Khalid, Castillo, Simon P., Hughes, Katherine, Davidson, Hannah, Boddy, Amy M., Abegglen, Lisa M., Minoli, Lucia, Iussich, Selina, Murchison, Elizabeth P., Graham, Trevor A., Spiro, Simon, Maley, Carlo C., Aresu, Luca, Palmieri, Chiara, Yuan, Yinyin

“…Cancers occur across species. Understanding what is consistent and varies across species can provide new insights into cancer initiation and evolution, with…”
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Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model by Pivetta, Eliana, Capuano, Alessandra, Scanziani, Eugenio, Minoli, Lucia, Andreuzzi, Eva, Mongiat, Maurizio, Baldassarre, Gustavo, Doliana, Roberto, Spessotto, Paola

“…Assessment of the host immune response pattern is of increasing importance as highly prognostic and diagnostic, in immune-related diseases and in some types of…”
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Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington’s disease by Birolini, Giulia, Valenza, Marta, Ottonelli, Ilaria, Talpo, Francesca, Minoli, Lucia, Cappelleri, Andrea, Bombaci, Mauro, Caccia, Claudio, Canevari, Caterina, Trucco, Arianna, Leoni, Valerio, Passoni, Alice, Favagrossa, Monica, Nucera, Maria Rosaria, Colombo, Laura, Paltrinieri, Saverio, Bagnati, Renzo, Duskey, Jason Thomas, Caraffi, Riccardo, Vandelli, Maria Angela, Taroni, Franco, Salmona, Mario, Scanziani, Eugenio, Biella, Gerardo, Ruozi, Barbara, Tosi, Giovanni, Cattaneo, Elena

“…Evidence that Huntington's disease (HD) is characterized by impaired cholesterol biosynthesis in the brain has led to strategies to increase its level in the…”
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Live or Heat-Killed Lactobacillus rhamnosus Aerosolization Decreases Adenomatous Lung Cancer Development in a Mouse Carcinogen-Induced Tumor Model by Le Noci, Valentino, Bernardo, Giancarla, Manenti, Giacomo, Infante, Gabriele, Khaleghi Hashemian, Dariush, Minoli, Lucia, Canesi, Simone, Bianchi, Francesca, Triulzi, Tiziana, Arioli, Stefania, De Cecco, Loris, Guglielmetti, Simone, Ambrogi, Federico, Recordati, Camilla, Gagliano, Nicoletta, Tagliabue, Elda, Sommariva, Michele, Sfondrini, Lucia

“…An immunosuppressive microenvironment in lung concurs to pre-malignant lesions progression to cancer. Here, we explore if perturbing lung microbiota, which…”
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Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth by Resovi, Andrea, Persichitti, Perla, Brunelli, Laura, Minoli, Lucia, Borsotti, Patrizia, Garattini, Giulia, Tironi, Matteo, Dugnani, Erica, Redegalli, Miriam, De Simone, Giulia, Pastorelli, Roberta, Bani, Maria Rosa, Piemonti, Lorenzo, Mosher, Deane F, Giavazzi, Raffaella, Taraboletti, Giulia, Belotti, Dorina

“…The pancreatic microenvironment has a defensive role against cancer but it can acquire tumor-promoting properties triggered by multiple mechanisms including…”
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POT1 mutations are frequent and associated with Ki-67 index in canine diffuse large B-cell lymphoma by Fanelli, Antonella, Marconato, Laura, Licenziato, Luca, Minoli, Lucia, Rouquet, Nicole, Aresu, Luca

“…Diffuse large B-cell lymphoma (DLBCL) represents one of the most frequent and deadliest neoplasia in dogs worldwide and is characterized by a remarkable degree…”
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Senescent Thyrocytes, Similarly to Thyroid Tumor Cells, Elicit M2-like Macrophage Polarization In Vivo by Mazzoni, Mara, Mauro, Giuseppe, Minoli, Lucia, Cleris, Loredana, Anania, Maria Chiara, Di Marco, Tiziana, Minna, Emanuela, Pagliardini, Sonia, Rizzetti, Maria Grazia, Manenti, Giacomo, Borrello, Maria Grazia, Scanziani, Eugenio, Greco, Angela

“…Inflammation plays a critical role in thyroid cancer onset and progression. We previously characterized the in vitro interplay between macrophages and…”
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Retrospective study of tumors from cattle slaughtered in Lombardy (Italy): preliminary evaluation on the establishment of a bovine cancer registry by Andrea Cappelleri, Lucia Minoli, Claudio Pigoli, Alessandro Costa, Loris Zaghini, Luca Bassanini, Massimo Sinelli, Marina Perri, Mario Vittorio Luini, Giovanna Tagliabue, Lucia Rita Gibelli, Eugenio Scanziani

“…Forty‑one tumors were detected in a population of 1,649,003 cattle slaughtered in 4 abattoirs in Lombardy over a 5‑year period, for an overall prevalence of…”
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Feline and Canine Cutaneous Lymphocytosis: Reactive Process or Indolent Neoplastic Disease? by Albanese, Francesco, Abramo, Francesca, Marino, Michele, Massaro, Maria, Marconato, Laura, Minoli, Lucia, Martini, Valeria, Aresu, Luca

“…Cutaneous lymphocytosis (CL) is an uncommon and controversial lymphoproliferative disorder described in dogs and cats. CL is generally characterized by a…”
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Cranial Spinal Spreading of Canine Brain Gliomas after Hypofractionated Volumetric-Modulated Arc Radiotherapy and Concomitant Temozolomide Chemotherapy: A Four-Case Report by Urso, Gaetano, Boncu, Alexandra Gabriela, Carrara, Nancy, Zaman, Dragos-Teodor, Malfassi, Luca, Marcarini, Silvia, Minoli, Lucia, Pavesi, Simone, Sala, Massimo, Scanziani, Eugenio, Dolera, Mario

“…Gliomas are the second-most-common primary brain tumors in dogs. Surgery and radiotherapy are established treatment approaches with similar median survival…”
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IL-1R8 Downregulation and Concomitant TLR7 and TLR9 Upregulation Are Related to the Pathogenesis of Canine Diffuse Large B-Cell Lymphoma by Riva, Federica, Filipe, Joel, Fanelli, Antonella, Marconato, Laura, Inglesi, Alessia, Scanziani, Eugenio, Soldati, Sabina, Licenziato, Luca, Comazzi, Stefano, Minoli, Lucia, Aresu, Luca

“…Diffuse large B-cell lymphoma (DLBCL) is the most common hematological malignancy in humans and dogs. Several studies disclosed some similarities between the…”
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Ex vivo evaluation of a technique for equine jejunocecal anastomosis using radiofrequency thermofusion and a Cushing oversew by Gandini, Marco, Cerullo, Anna, Gallo, Livio, Iussich, Selina, Minoli, Lucia, Giusto, Gessica

“…Objective To describe a technique for a side‐to‐side jejunocecal anastomosis in horses using radiofrequency thermofusion (TF) of the intestines supported by a…”
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LKB1 Deficiency Renders NSCLC Cells Sensitive to ERK Inhibitors by Caiola, Elisa, Iezzi, Alice, Tomanelli, Michele, Bonaldi, Elisa, Scagliotti, Arianna, Colombo, Marika, Guffanti, Federica, Micotti, Edoardo, Garassino, Marina Chiara, Minoli, Lucia, Scanziani, Eugenio, Broggini, Massimo, Marabese, Mirko

“…Serine/threonine kinase 11 (LKB1/STK11) is one of the most mutated genes in NSCLC accounting for approximately one-third of cases and its activity is impaired…”
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