Search Results - "Lucia Carbone"

Epigenetic maintenance of topological domains in the highly rearranged gibbon genome by Lazar, Nathan H, Nevonen, Kimberly A, O'Connell, Brendan, McCann, Christine, O'Neill, Rachel J, Green, Richard E, Meyer, Thomas J, Okhovat, Mariam, Carbone, Lucia

“…The relationship between evolutionary genome remodeling and the three-dimensional structure of the genome remain largely unexplored. Here, we use the heavily…”
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Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion by Daughtry, Brittany L, Rosenkrantz, Jimi L, Lazar, Nathan H, Fei, Suzanne S, Redmayne, Nash, Torkenczy, Kristof A, Adey, Andrew, Yan, Melissa, Gao, Lina, Park, Byung, Nevonen, Kimberly A, Carbone, Lucia, Chavez, Shawn L

“…Aneuploidy that arises during meiosis and/or mitosis is a major contributor to early embryo loss. We previously showed that human preimplantation embryos…”
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Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development by Brooks, Kelsey E, Daughtry, Brittany L, Davis, Brett, Yan, Melissa Y, Fei, Suzanne S, Shepherd, Selma, Carbone, Lucia, Chavez, Shawn L

“…Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure or spontaneous miscarriage in both natural and assisted…”
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Coevolution of Genome Architecture and Social Behavior by Rubenstein, Dustin R., Ågren, J. Arvid, Carbone, Lucia, Elde, Nels C., Hoekstra, Hopi E., Kapheim, Karen M., Keller, Laurent, Moreau, Corrie S., Toth, Amy L., Yeaman, Sam, Hofmann, Hans A.

“…Although social behavior can have a strong genetic component, it can also result in selection on genome structure and function, thereby influencing the…”
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RNA-Seq of human whole blood: Evaluation of globin RNA depletion on Ribo-Zero library method by Harrington, Christina A., Fei, Suzanne S., Minnier, Jessica, Carbone, Lucia, Searles, Robert, Davis, Brett A., Ogle, Kimberly, Planck, Stephen R., Rosenbaum, James T., Choi, Dongseok

“…Peripheral blood is a highly accessible biofluid providing a rich source of information about human physiology and health status. However, for studies of the…”
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RNA-seq from archival FFPE breast cancer samples: molecular pathway fidelity and novel discovery by Pennock, Nathan D, Jindal, Sonali, Horton, Wesley, Sun, Duanchen, Narasimhan, Jayasri, Carbone, Lucia, Fei, Suzanne S, Searles, Robert, Harrington, Christina A, Burchard, Julja, Weinmann, Sheila, Schedin, Pepper, Xia, Zheng

“…Formalin-fixed, paraffin-embedded (FFPE) tissues for RNA-seq have advantages over fresh frozen tissue including abundance and availability, connection to rich…”
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Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha by Hardin, Aaron, Nevonen, Kimberly A, Eckalbar, Walter L, Carbone, Lucia, Ahituv, Nadav

“…Abstract Mastomys are the most widespread African rodent and carriers of various diseases such as the plague or Lassa virus. In addition, mastomys have rapidly…”
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TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function by Okhovat, Mariam, VanCampen, Jake, Nevonen, Kimberly A., Harshman, Lana, Li, Weiyu, Layman, Cora E., Ward, Samantha, Herrera, Jarod, Wells, Jackson, Sheng, Rory R., Mao, Yafei, Ndjamen, Blaise, Lima, Ana C., Vigh-Conrad, Katinka A., Stendahl, Alexandra M., Yang, Ran, Fedorov, Lev, Matthews, Ian R., Easow, Sarah A., Chan, Dylan K., Jan, Taha A., Eichler, Evan E., Rugonyi, Sandra, Conrad, Donald F., Ahituv, Nadav, Carbone, Lucia

“…Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of…”
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Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia by Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.

“…Acute Myeloid Leukemia (AML) develops due to the acquisition of mutations from multiple functional classes. Here, we demonstrate that activating mutations in…”
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Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation by Rosenkrantz, Jimi L, Gaffney, Jessica E, Roberts, Victoria H J, Carbone, Lucia, Chavez, Shawn L

“…Proper placentation, including trophoblast differentiation and function, is essential for the health and well-being of both the mother and baby throughout…”
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Transcriptomic and epigenomic characterization of the developing bat wing by Eckalbar, Walter L, Schlebusch, Stephen A, Mason, Mandy K, Gill, Zoe, Parker, Ash V, Booker, Betty M, Nishizaki, Sierra, Muswamba-Nday, Christiane, Terhune, Elizabeth, Nevonen, Kimberly A, Makki, Nadja, Friedrich, Tara, VanderMeer, Julia E, Pollard, Katherine S, Carbone, Lucia, Wall, Jeff D, Illing, Nicola, Ahituv, Nadav

“…Nadav Ahituv, Nicola Illing, Jeff Wall and colleagues sequence the genome of the bat Miniopterus natalensis and perform RNA-seq and ChIP-seq (H3K27ac and…”
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DNA Methylation Analysis of Turner Syndrome BAV by Gutierrez, Jacob, Davis, Brett A, Nevonen, Kimberly A, Ward, Samantha, Carbone, Lucia, Maslen, Cheryl L

“…Turner Syndrome (TS) is a rare cytogenetic disorder caused by the complete loss or structural variation of the second sex chromosome. The most common cause of…”
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Examining phylogenetic relationships among gibbon genera using whole genome sequence data using an approximate bayesian computation approach by Veeramah, Krishna R, Woerner, August E, Johnstone, Laurel, Gut, Ivo, Gut, Marta, Marques-Bonet, Tomas, Carbone, Lucia, Wall, Jeff D, Hammer, Michael F

“…Gibbons are believed to have diverged from the larger great apes ∼16.8 MYA and today reside in the rainforests of Southeast Asia. Based on their diploid…”
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Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia by Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.

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Age-Associated DNA Methylation Patterns Are Shared Between the Hippocampus and Peripheral Blood Cells by Harris, Christopher J, Davis, Brett A, Zweig, Jonathan A, Nevonen, Kimberly A, Quinn, Joseph F, Carbone, Lucia, Gray, Nora E

“…As the population ages, interest in identifying biomarkers of healthy aging and developing antiaging interventions has increased. DNA methylation has emerged…”
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A comprehensive molecular cytogenetic analysis of chromosome rearrangements in gibbons by Capozzi, Oronzo, Carbone, Lucia, Stanyon, Roscoe R, Marra, Annamaria, Yang, Fengtang, Whelan, Christopher W, de Jong, Pieter J, Rocchi, Mariano, Archidiacono, Nicoletta

“…Chromosome rearrangements in small apes are up to 20 times more frequent than in most mammals. Because of their complexity, the full extent of chromosome…”
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Stable Histone Methylation Changes at Proteoglycan Network Genes Following Ethanol Exposure by Gavin, David P, Hashimoto, Joel G, Lazar, Nathan H, Carbone, Lucia, Crabbe, John C, Guizzetti, Marina

“…Alcohol use disorder (AUD) is a chronic mental illness in which patients often achieve protracted periods of abstinence prior to relapse. Epigenetic mechanisms…”
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Inference of transposable element ancestry by Wacholder, Aaron C, Cox, Corey, Meyer, Thomas J, Ruggiero, Robert P, Vemulapalli, Vijetha, Damert, Annette, Carbone, Lucia, Pollock, David D

“…Most common methods for inferring transposable element (TE) evolutionary relationships are based on dividing TEs into subfamilies using shared diagnostic…”
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Evolutionary breakpoints in the gibbon suggest association between cytosine methylation and karyotype evolution by Carbone, Lucia, Harris, R Alan, Vessere, Gery M, Mootnick, Alan R, Humphray, Sean, Rogers, Jane, Kim, Sung K, Wall, Jeffrey D, Martin, David, Jurka, Jerzy, Milosavljevic, Aleksandar, de Jong, Pieter J

“…Gibbon species have accumulated an unusually high number of chromosomal changes since diverging from the common hominoid ancestor 15-18 million years ago. The…”
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Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas by Macchia, Gemma, Nord, Karolin H., Zoli, Monica, Purgato, Stefania, D'Addabbo, Pietro, Whelan, Christopher W., Carbone, Lucia, Perini, Giovanni, Mertens, Fredrik, Rocchi, Mariano, Storlazzi, Clelia Tiziana

“…Gene amplification is relatively common in tumors. In certain subtypes of sarcoma, it often occurs in the form of ring and/or giant rod‐shaped marker (RGM)…”
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