Search Results - "Lucia, Zanotti"
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CCRL2 regulates M1/M2 polarization during EAE recovery phase
Published in Journal of leukocyte biology (01-06-2016)“…CCRL2 in the control of inflammation and demyelination in EAE. Chemokine (CC motif) receptor‐like 2 is a 7‐transmembrane protein related to the family of the…”
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Role of epigenetics in the clinical evolution of COVID-19 disease. Epigenome-wide association study identifies markers of severe outcome
Published in European journal of medical research (17-02-2023)“…COVID-19 has a wide spectrum of clinical manifestations and given its impact on morbidity and mortality, there is an unmet medical need to discover endogenous…”
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Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study
Published in Clinical epigenetics (20-08-2024)“…The epigenetic status of patients 6-month post-COVID-19 infection remains largely unexplored. The existence of long-COVID, or post-acute sequelae of SARS-CoV-2…”
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Regeneration and repair in multiple sclerosis: The role of cell transplantation
Published in Neuroscience letters (12-06-2009)“…Physiological ( spontaneous) and reactive ( reparative) regenerative processes are fundamental part of life and greatly differ among the different animals and…”
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Mesenchymal stem cells: myths and reality
Published in Swiss medical weekly (2015)“…Mesenchymal stem cells (MSCs; also called mesenchymal stromal cells) have received much attention during the last two decades, at first because of their…”
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Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function
Published in PloS one (19-06-2009)“…The systemic injection of neural stem/precursor cells (NPCs) provides remarkable amelioration of the clinico-pathological features of experimental autoimmune…”
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18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis
Published in Journal of neuroinflammation (05-02-2018)“…Background Positron emission tomography (PET) using translocator protein (TSPO) ligands has been used to detect neuroinflammatory processes in neurological…”
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Effect of fetal bovine serum in culture media on MS analysis of mesenchymal stromal cells secretome
Published in EuPA open proteomics (01-03-2016)“…[Display omitted] Optimized protocol to collect the secretome of human BM-MSC.Truly secreted proteins may be difficult to detect for fetal bovine serum…”
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Synuclein Proteins in Cancer Development and Progression
Published in Biomolecules (Basel, Switzerland) (01-06-2023)“…Synucleins are a family of small, soluble proteins mainly expressed in neural tissue and in certain tumors. Since their discovery, tens of thousands of…”
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Overcoming Therapy Resistance in Colorectal Cancer: Targeting the Rac1 Signaling Pathway as a Potential Therapeutic Approach
Published in Cells (Basel, Switzerland) (26-10-2024)“…Colorectal cancer (CRC) is the third most commonly diagnosed type of cancer worldwide and is responsible for numerous deaths. 5-fluorouracil (5-FU) is an…”
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Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2015)“…Background & Aims Mesenchymal stem cells (MSCs) are pluripotent cells that can promote expansion of immune regulatory cells and might be developed for the…”
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Reboxetine Plus Oxybutynin for OSA Treatment: A 1-Week, Randomized, Placebo-Controlled, Double-Blind Crossover Trial
Published in Chest (01-01-2022)“…The recent discovery that a combination of noradrenergic and antimuscarinic drugs improved upper airway muscle function during sleep and reduced OSA severity…”
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Proteomic analysis of the secretome of human bone marrow-derived mesenchymal stem cells primed by pro-inflammatory cytokines
Published in Journal of proteomics (23-08-2017)“…Mesenchymal stem cells (MSC) represent an impressive opportunity in term of regenerative medicine and immunosuppressive therapy. Although it is clear that upon…”
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Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse
Published in Cancer discovery (02-06-2022)“…Immune escape represents a major driver of acute myeloid leukemia (AML) reemergence after allogeneic hematopoietic cell transplantation (allo-HCT), with up to…”
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P063 DIFFERENCES IN CARDIOVASCULAR RISK IN THE GENERAL POPULATION OF LOW AND HIGH-ALTITUDE RESIDENTS IN PERU. HIGH ALTITUDE CARDIOVASCULAR RESEARCH – LATIN AMERICA POPULATION STUDY
Published in Journal of hypertension (01-09-2024)“…Background and Objective. Previous data in a convenience sample of highlanders showed an elevated prevalence of masked hypertension. However, comparative…”
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RESIDENCE AT HIGH ALTITUDE IS ASSOCIATED WITH LOWER CONVENTIONAL AND AMBULATORY BLOOD PRESSURE THAN LIVING AT SEA LEVEL IN THE GENERAL POPULATION OF PERU. HIGHCARE-LAPS STUDY
Published in Journal of hypertension (01-05-2024)“…Objective: Acute exposure to hypoxia at high altitude (HA) leads to an increase in blood pressure (BP) in healthy individuals and in hypertensive patients…”
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Reboxetine Plus Oxybutynin for OSA Treatment
Published in Chest (01-01-2022)“…The recent discovery that a combination of noradrenergic and antimuscarinic drugs improved upper airway muscle function during sleep and reduced OSA severity…”
Get full text
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Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
Published in Nature (14-07-2005)“…In degenerative disorders of the central nervous system (CNS), transplantation of neural multipotent (stem) precursor cells (NPCs) is aimed at replacing…”
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Integrated Epigenetic Profiling Identifies EZH2 As a Therapeutic Target to Re-Establish Immune Recognition of Leukemia Relapses with Loss of HLA Class II Expression
Published in Blood (13-11-2019)“…Background It is becoming increasingly recognized that evasion from immune control represents one of the main drivers of acute myeloid leukemia (AML) relapse…”
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