Search Results - "Luche, Hérve"

Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model by Almosailleakh, Marwa, Bentivegna, Sofia, Narcisi, Samuele, Benquet, Sébasitien J, Gillberg, Linn, Montaño-Almendras, Carmen P, Savickas, Simonas, Schoof, Erwin M, Wegener, Amelie, Luche, Hérve, Jensen, Henrik E, Côme, Christophe, Grønbæk, Kirsten

“…The KN Motif and AnKyrin Repeat Domain 1 (KANK1) is proposed as a tumour suppressor gene, as its expression is reduced or absent in several types of tumour…”
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Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin by Tamoutounour, Samira, Guilliams, Martin, Montanana Sanchis, Frédéric, Liu, Hong, Terhorst, Dorothea, Malosse, Camille, Pollet, Emeline, Ardouin, Laurence, Luche, Hervé, Sanchez, Cindy, Dalod, Marc, Malissen, Bernard, Henri, Sandrine

“…In the skin, the lack of markers permitting the unambiguous identification of macrophages and of conventional and monocyte-derived dendritic cells (DCs)…”
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Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species by Guilliams, Martin, Dutertre, Charles-Antoine, Scott, Charlotte L., McGovern, Naomi, Sichien, Dorine, Chakarov, Svetoslav, Van Gassen, Sofie, Chen, Jinmiao, Poidinger, Michael, De Prijck, Sofie, Tavernier, Simon J., Low, Ivy, Irac, Sergio Erdal, Mattar, Citra Nurfarah, Sumatoh, Hermi Rizal, Low, Gillian Hui Ling, Chung, Tam John Kit, Chan, Dedrick Kok Hong, Tan, Ker Kan, Hon, Tony Lim Kiat, Fossum, Even, Bogen, Bjarne, Choolani, Mahesh, Chan, Jerry Kok Yen, Larbi, Anis, Luche, Hervé, Henri, Sandrine, Saeys, Yvan, Newell, Evan William, Lambrecht, Bart N., Malissen, Bernard, Ginhoux, Florent

“…Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains…”
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Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells by Miyao, Takahisa, Floess, Stefan, Setoguchi, Ruka, Luche, Hervé, Fehling, Hans Joerg, Waldmann, Herman, Huehn, Jochen, Hori, Shohei

“…The emerging notion of environment-induced reprogramming of Foxp3+ regulatory T (Treg) cells into helper T (Th) cells remains controversial. By genetic fate…”
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CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization by Langlet, Christelle, Tamoutounour, Samira, Henri, Sandrine, Luche, Hervé, Ardouin, Laurence, Grégoire, Claude, Malissen, Bernard, Guilliams, Martin

“…Although most vaccines are administered i.m., little is known about the dendritic cells (DCs) that are present within skeletal muscles. In this article, we…”
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Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics by Voisinne, Guillaume, Kersse, Kristof, Chaoui, Karima, Lu, Liaoxun, Chaix, Julie, Zhang, Lichen, Goncalves Menoita, Marisa, Girard, Laura, Ounoughene, Youcef, Wang, Hui, Burlet-Schiltz, Odile, Luche, Hervé, Fiore, Frédéric, Malissen, Marie, Gonzalez de Peredo, Anne, Liang, Yinming, Roncagalli, Romain, Malissen, Bernard

“…The activation of T cells by the T cell antigen receptor (TCR) results in the formation of signaling protein complexes (signalosomes), the composition of which…”
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Identification and targeting of the ROSA26 locus in human embryonic stem cells by Irion, Stefan, Keller, Gordon, Luche, Hervé, Fehling, Hans Joerg, Gadue, Paul, Kennedy, Marion

“…The derivation of human embryonic stem (hES) cells has opened new avenues for studies on human development and provided a potential source of cells for…”
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Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery by Ardouin, Laurence, Luche, Hervé, Chelbi, Rabie, Carpentier, Sabrina, Shawket, Alaa, Montanana Sanchis, Frédéric, Santa Maria, Camille, Grenot, Pierre, Alexandre, Yannick, Grégoire, Claude, Fries, Anissa, Vu Manh, Thien-Phong, Tamoutounour, Samira, Crozat, Karine, Tomasello, Elena, Jorquera, Audrey, Fossum, Even, Bogen, Bjarne, Azukizawa, Hiroaki, Bajenoff, Marc, Henri, Sandrine, Dalod, Marc, Malissen, Bernard

“…Dendritic cells (DCs) are instrumental in the initiation of T cell responses, but how thymic and peripheral tolerogenic DCs differ globally from Toll-like…”
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Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions by Varol, Chen, Vallon-Eberhard, Alexandra, Elinav, Eran, Aychek, Tegest, Shapira, Yami, Luche, Hervé, Fehling, Hans Jörg, Hardt, Wolf-Dietrich, Shakhar, Guy, Jung, Steffen

“…The intestinal immune system discriminates between tolerance toward the commensal microflora and robust responses to pathogens. Maintenance of this critical…”
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Faithful activation of an extra‐bright red fluorescent protein in “knock‐in” Cre‐reporter mice ideally suited for lineage tracing studies by Luche, Hervé, Weber, Odile, Nageswara Rao, Tata, Blum, Carmen, Fehling, Hans Jörg

“…The considerable potential of Cre recombinase as a tool for in vivo fate‐mapping studies depends on the availability of reliable reporter mice. By targeting a…”
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In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis by Siffrin, Volker, Radbruch, Helena, Glumm, Robert, Niesner, Raluca, Paterka, Magdalena, Herz, Josephine, Leuenberger, Tina, Lehmann, Sabrina M., Luenstedt, Sarah, Rinnenthal, Jan Leo, Laube, Gregor, Luche, Hervé, Lehnardt, Seija, Fehling, Hans-Joerg, Griesbeck, Oliver, Zipp, Frauke

“…Neuronal damage in autoimmune neuroinflammation is the correlate for long-term disability in multiple sclerosis (MS) patients. Here, we investigated the role…”
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Multicolor fate mapping of Langerhans cell homeostasis by Ghigo, Clément, Mondor, Isabelle, Jorquera, Audrey, Nowak, Jonathan, Wienert, Stephan, Zahner, Sonja P, Clausen, Björn E, Luche, Hervé, Malissen, Bernard, Klauschen, Frederick, Bajénoff, Marc

“…Langerhans cells (LCs) constitute a network of immune sentinels in the skin epidermis that is seeded during embryogenesis. Whereas the development of LCs has…”
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CD5L as a promising biological therapeutic for treating sepsis by Oliveira, Liliana, Silva, M. Carolina, Gomes, Ana P., Santos, Rita F., Cardoso, Marcos S., Nóvoa, Ana, Luche, Hervé, Cavadas, Bruno, Amorim, Irina, Gärtner, Fátima, Malissen, Bernard, Mallo, Moisés, Carmo, Alexandre M.

“…Sepsis results from systemic, dysregulated inflammatory responses to infection, culminating in multiple organ failure. Here, we demonstrate the utility of CD5L…”
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Single‐cell transcriptomics uncovers an instructive T‐cell receptor role in adult γδ T‐cell lineage commitment by Scaramuzzino, Sara, Potier, Delphine, Ordioni, Robin, Grenot, Pierre, Payet‐Bornet, Dominique, Luche, Hervé, Malissen, Bernard

“…After entering the adult thymus, bipotent T‐cell progenitors give rise to αβ or γδ T cells. To determine whether the γδ T‐cell receptor (TCR) has an…”
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Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor by Narni-Mancinelli, Emilie, Chaix, Julie, Fenis, Aurore, Kerdiles, Yann M., Yessaad, Nadia, Reynders, Ana, Gregoire, Claude, Luche, Herve, Ugolini, Sophie, Tomasello, Elena, Walzer, Thierry, Vivier, Eric

“…NKp46 is a cell surface receptor expressed on natural killer (NK) cells, on a minute subset of T cells, and on a population of innate lymphoid cells that…”
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Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type by Crozat, Karine, Tamoutounour, Samira, Vu Manh, Thien-Phong, Fossum, Even, Luche, Hervé, Ardouin, Laurence, Guilliams, Martin, Azukizawa, Hiroaki, Bogen, Bjarne, Malissen, Bernard, Henri, Sandrine, Dalod, Marc

“…Subsets of dendritic cells (DCs) have been described according to their functions and anatomical locations. Conventional DC subsets are defined by reciprocal…”
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Cytomegalovirus infection of the fetal brain: intake of aspirin during pregnancy blunts neurodevelopmental pathogenesis in the offspring by Tarhini, Sarah, Crespo-Quiles, Carla, Buhler, Emmanuelle, Pineau, Louison, Pallesi-Pocachard, Emilie, Villain, Solène, Saha, Saswati, Silvagnoli, Lucas, Stamminger, Thomas, Luche, Hervé, Cardoso, Carlos, Pais de Barros, Jean-Paul, Burnashev, Nail, Szepetowski, Pierre, Bauer, Sylvian

“…Background Congenital cytomegalovirus (CMV) infections represent one leading cause of human neurodevelopmental disorders. Despite their high prevalence and…”
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Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model by Caravagna, Céline, Jaouën, Alexandre, Desplat-Jégo, Sophie, Fenrich, Keith K., Bergot, Elise, Luche, Hervé, Grenot, Pierre, Rougon, Geneviève, Malissen, Marie, Debarbieux, Franck

“…In both multiple sclerosis and its model experimental autoimmune encephalomyelitis (EAE), the extent of resident microglia activation and infiltration of…”
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Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation by Nitschké, Maximilian, Aebischer, David, Abadier, Michael, Haener, Simone, Lucic, Matije, Vigl, Benjamin, Luche, Hervé, Fehling, Hans Jörg, Biehlmaier, Oliver, Lyck, Ruth, Halin, Cornelia

“…Dendritic cell (DC) migration via lymphatic vessels to draining lymph nodes (dLNs) is crucial for the initiation of adaptive immunity. We imaged this process…”
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Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice by Ricard, Clément, Tchoghandjian, Aurélie, Luche, Hervé, Grenot, Pierre, Figarella-Branger, Dominique, Rougon, Geneviève, Malissen, Marie, Debarbieux, Franck

“…Inflammatory cells, an integral component of tumor evolution, are present in Glioblastomas multiforme (GBM). To address the cellular basis and dynamics of the…”
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