Search Results - "Lucet, I."

HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death by Jacobsen, A V, Lowes, K N, Tanzer, M C, Lucet, I S, Hildebrand, J M, Petrie, E J, van Delft, M F, Liu, Z, Conos, S A, Zhang, J-G, Huang, D C S, Silke, J, Lessene, G, Murphy, J M

“…Necroptosis is a caspase-independent form of regulated cell death that has been implicated in the development of a range of inflammatory, autoimmune and…”
Get full text

Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution by Chouly, C, Pouliquen, D, Lucet, I, Jeune, J J, Jallet, P

“…Twelve superparamagnetic Magnetite-Dextran (MD) nanoparticles potentially useful as contrast agents for Magnetic Resonance Imaging (MRI), with different sizes,…”
Get more information

Direct interaction between the cell division protein FtsZ and the cell differentiation protein SpoIIE by Lucet, Isabelle, Feucht, Andrea, Yudkin, Michael D., Errington, Jeffery

“…SpoIIE is a bifunctional protein with two critical roles in the establishment of cell fate in Bacillus subtilis. First, SpoIIE is needed for the normal…”
Get full text

DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn4451 family by Adams, Vicki, Lucet, Isabelle S., Lyras, Dena, Rood, Julian I.

“…Summary Site‐specific recombination is an important mechanism for genetic exchange. Insertional recombination mediated by the recently delineated large…”
Get full text

Fate of the SpoIIAB-ADP Liberated after SpoIIAB Phosphorylates SpoIIAA of Bacillus subtilis by Lee, C S, Lucet, I, Yudkin, M D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity by Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.

“…Janus kinases (JAKs) are key effectors in controlling immune responses and maintaining hematopoiesis. SOCS3 (suppressor of cytokine signaling-3) is a major…”
Get full text

Dissecting Specificity in the Janus Kinases: The Structures of JAK-Specific Inhibitors Complexed to the JAK1 and JAK2 Protein Tyrosine Kinase Domains by Williams, Neal K., Bamert, Rebecca S., Patel, Onisha, Wang, Christina, Walden, Patricia M., Wilks, Andrew F., Fantino, Emmanuelle, Rossjohn, Jamie, Lucet, Isabelle S.

“…The Janus kinases (JAKs) are a pivotal family of protein tyrosine kinases (PTKs) that play prominent roles in numerous cytokine signaling pathways, with…”
Get full text

The FxRxHrS Motif: A Conserved Region Essential for DNA Binding of the VirR Response Regulator from Clostridium perfringens by McGowan, Sheena, Lucet, Isabelle S, Cheung, Jackie K, Awad, Milena M, Whisstock, James C, Rood, Julian I

“…The VirSR two-component signal transduction pathway regulates virulence and toxin production in Clostridium perfringens, the causative agent of gas gangrene…”
Get full text

Liver-directed superparamagnetic iron oxide: quantitation of T2 relaxation effects by Pouliquen, D, Lucet, I, Chouly, C, Perdrisot, R, Le Jeune, J J, Jallet, P

“…A new liver-directed superparamagnetic iron oxide nanoparticle preparation, MDL, is described. MDL is derived from previously developed MD particles only by…”
Get more information

The 2.7 Å Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain by Walter, Mark, Lucet, Isabelle S., Patel, Onisha, Broughton, Sophie E., Bamert, Rebecca, Williams, Neal K., Fantino, Emmanuelle, Wilks, Andrew F., Rossjohn, Jamie

“…c-Fms, a member of the Platelet-derived Growth Factor (PDGF) receptor family of receptor tyrosine kinases (RTKs), is the receptor for macrophage colony…”
Get full text

Cytological and biochemical characterization of the FtsA cell division protein of Bacillus subtilis by Feucht, Andrea, Lucet, Isabelle, Yudkin, Michael D., Errington, Jeffery

“…The actin‐like protein FtsA is present in many eubacteria, and genetic experiments have shown that it plays an important, sometimes essential, role in cell…”
Get full text

The large resolvase TnpX is the only transposon‐encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements by Lyras, Dena, Adams, Vicki, Lucet, Isabelle, Rood, Julian I.

“…Summary Chloramphenicol resistance in Clostridium perfringens and Clostridium difficile is often encoded by catP genes located within the 6.3 kb integrative…”
Get full text

Differential Recognition of CD1d-a-Galactosyl Ceramide by the Vb8.2 and Vb7 Semi-invariant NKT T Cell Receptors by Pellicci, D G, Patel, O, Kjer-Nielsen, L, Pang, S S, Sullivan, L C, Kyparissoudis, K, Brooks, A G, Reid, H H, Gras, S, Lucet, I S, Koh, R, Smyth, MJ, Mallevaey, T, Godfrey, DI

“…The semi-invariant natural killer T cell receptor (NKT TCR) recognizes CD1d-lipid antigens. Although the TCRa chain is typically invariant, the b chain…”
Get full text

Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis by Marland, Zara, Beddoe, Travis, Zaker-Tabrizi, Leyla, Lucet, Isabelle S., Brammananth, Rajini, Whisstock, James C., Wilce, Matthew C.J., Coppel, Ross L., Crellin, Paul K., Rossjohn, Jamie

“…The waxy cell wall is crucial to the survival of mycobacteria within the infected host. The cell wall is a complex structure rich in unusual molecules that…”
Get full text

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor by Lucet, Isabelle S., Fantino, Emmanuelle, Styles, Michelle, Bamert, Rebecca, Patel, Onisha, Broughton, Sophie E., Walter, Mark, Burns, Christopher J., Treutlein, Herbert, Wilks, Andrew F., Rossjohn, Jamie

“…JAK2, a member of the Janus kinase (JAK) family of protein tyrosine kinases (PTKs), is an important intracellular mediator of cytokine signaling. Mutations of…”
Get full text

Purification, Kinetic Properties, and Intracellular Concentration of SpoIIE, an Integral Membrane Protein That Regulates Sporulation in Bacillus subtilis by Lucet, I, Borriss, R, Yudkin, M D

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The Bacillus subtilis regulator protein SpoIIE shares functional and structural similarities with eukaryotic protein phosphatases 2C by Schroeter, Ragnar, Schlisio, Susanne, Lucet, Isabelle, Yudkin, Michael, Borriss, Rainer

“…Dephosphorylation of SpoIIAA-P by SpoIIE is strictly dependent on the presence of the bivalent metal ions Mn 2+ or Mg 2+. Replacement by Ala of one of the four…”
Get full text

The Bacillus subtilis regulator protein SpoIIE shares functional and structural similarities with eukaryotic protein phosphatases 2C by Schroeter, Ragnar, Schlisio, Susanne, Lucet, Isabelle, Yudkin, Michael, Borriss, Rainer

“…Abstract Dephosphorylation of SpoIIAA-P by SpoIIE is strictly dependent on the presence of the bivalent metal ions Mn2+ or Mg2+. Replacement by Ala of one of…”
Get full text

Genotype, phenotype, and protein structure in a regulator of sporulation: effects of mutations in the spoIIAA gene of Bacillus subtilis by Barillà, D, Lucet, I, Kuhlmann, A, Yudkin, M D

“…SpoIIAA, a phosphorylatable protein, is essential to the regulation of sigmaF, the first sporulation-specific transcription factor of Bacillus subtilis. The…”
Get full text

NAD+ Kinase Activities in Euglena Gracilis and Phaseolus Vulgaris by Morere-Le Paven, M.-C., Montrichard, F., Lucet, I., Jalouzot, R., Laval-Martin, D. L.

Get full text