Search Results - "Luce, Amalia"

Mitochondria as playmakers of apoptosis, autophagy and senescence by Abate, Marianna, Festa, Agostino, Falco, Michela, Lombardi, Angela, Luce, Amalia, Grimaldi, Anna, Zappavigna, Silvia, Sperlongano, Pasquale, Irace, Carlo, Caraglia, Michele, Misso, Gabriella

“…Mitochondria are the key energy-producing organelles and cellular source of reactive species. They are responsible for managing cell life and death by a…”
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Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy? by Martellucci, Stefano, Orefice, Nicola Salvatore, Angelucci, Adriano, Luce, Amalia, Caraglia, Michele, Zappavigna, Silvia

“…Extracellular Vesicles (EVs) represent a heterogeneous population of membranous cell-derived structures, including cargo-oriented exosomes and microvesicles…”
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LncRNAs and Immunity: Coding the Immune System with Noncoding Oligonucleotides by Bocchetti, Marco, Scrima, Marianna, Melisi, Federica, Luce, Amalia, Sperlongano, Rossella, Caraglia, Michele, Zappavigna, Silvia, Cossu, Alessia Maria

“…Long noncoding RNAs (lncRNAs) represent key regulators of gene transcription during the inflammatory response. Recent findings showed lncRNAs to be…”
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MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer by Ferri, Carmela, Di Biase, Anna, Bocchetti, Marco, Zappavigna, Silvia, Wagner, Sarah, Le Vu, Pauline, Luce, Amalia, Cossu, Alessia Maria, Vadakekolathu, Jayakumar, Miles, Amanda, Boocock, David J, Robinson, Alex, Schwerdtfeger, Melanie, Tirino, Virginia, Papaccio, Federica, Caraglia, Michele, Regad, Tarik, Desiderio, Vincenzo

“…The long non-coding RNA (lncRNA), MALAT1, plays a key role in the development of different cancers, and its expression is associated with worse prognosis in…”
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The Role of microRNAs in Development of Colitis-Associated Colorectal Cancer by Bocchetti, Marco, Ferraro, Maria Grazia, Ricciardiello, Filippo, Ottaiano, Alessandro, Luce, Amalia, Cossu, Alessia Maria, Scrima, Marianna, Leung, Wing-Yan, Abate, Marianna, Stiuso, Paola, Caraglia, Michele, Zappavigna, Silvia, Yau, Tung On

“…Colorectal cancer (CRC) is the third most deadly cancer worldwide, and inflammatory bowel disease (IBD) is one of the critical factors in CRC carcinogenesis…”
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Antitumor activity of dual blockade of PD-L1 and MEK in NSCLC patients derived three-dimensional spheroid cultures by Della Corte, Carminia Maria, Barra, Giusi, Ciaramella, Vincenza, Di Liello, Raimondo, Vicidomini, Giovanni, Zappavigna, Silvia, Luce, Amalia, Abate, Marianna, Fiorelli, Alfonso, Caraglia, Michele, Santini, Mario, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Morgillo, Floriana

“…Anti-PD-1/PD-L1 drugs are effective as monotherapy in a proportion of NSCLC patients and there is a strong rationale for combining them with targeted therapy…”
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A Combination of Microarray-Based Profiling and Biocomputational Analysis Identified miR331-3p and hsa-let-7d-5p as Potential Biomarkers of Ulcerative Colitis Progression to Colorectal Cancer by Chacon-Millan, Pilar, Lama, Stefania, Del Gaudio, Nunzio, Gravina, Antonietta Gerarda, Federico, Alessandro, Pellegrino, Raffaele, Luce, Amalia, Altucci, Lucia, Facchiano, Angelo, Caraglia, Michele, Stiuso, Paola

“…Ulcerative colitis (UC), an inflammatory bowel disease (IBD), may increase the risk of colorectal cancer (CRC) by activating chronic proinflammatory pathways…”
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Insight toward the MicroRNA Profiling of Laryngeal Cancers: Biological Role and Clinical Impact by Takeuchi, Takashi, Kawasaki, Hiromichi, Luce, Amalia, Cossu, Alessia Maria, Misso, Gabriella, Scrima, Marianna, Bocchetti, Marco, Ricciardiello, Filippo, Caraglia, Michele, Zappavigna, Silvia

“…Head and neck squamous cell carcinoma (HNSCC), a heterogeneous disease arising from various anatomical locations including the larynx, is a leading cause of…”
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A Proteomic Approach Reveals That miR-423-5p Modulates Glucidic and Amino Acid Metabolism in Prostate Cancer Cells by Luce, Amalia, Lombardi, Angela, Ferri, Carmela, Zappavigna, Silvia, Tathode, Madhura S, Miles, Amanda K, Boocock, David J, Vadakekolathu, Jayakumar, Bocchetti, Marco, Alfano, Roberto, Sperlongano, Rossella, Ragone, Angela, Sapio, Luigi, Desiderio, Vincenzo, Naviglio, Silvio, Regad, Tarik, Caraglia, Michele

“…Recently, we have demonstrated that miR-423-5p modulates the growth and metastases of prostate cancer (PCa) cells both in vitro and in vivo. Here, we have…”
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Immune cell infiltration and inflammatory landscape in primary brain tumours by Luce, Amalia, Abate, Marianna, Scognamiglio, Giosuè, Montella, Marco, Iervolino, Domenico, Campione, Severo, Di Mauro, Annabella, Sepe, Orlando, Gigantino, Vincenzo, Tathode, Madhura S, Ferrara, Gerardo, Monaco, Roberto, De Dominicis, Gianfranco, Misso, Gabriella, Gentile, Vittorio, Franco, Renato, Zappavigna, Silvia, Caraglia, Michele

“…Primary malignant brain tumours are more than one-third of all brain tumours and despite the molecular investigation to identify cancer driver mutations, the…”
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Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer by Bocchetti, Marco, Luce, Amalia, Iannarone, Clara, Pasquale, Lucia Stefania, Falco, Michela, Tammaro, Chiara, Abate, Marianna, Ferraro, Maria Grazia, Addeo, Raffaele, Ricciardiello, Filippo, Motta, Giovanni, De Stefano, Luca, Caraglia, Francesco, Ceccarelli, Anna, Zappavigna, Silvia, Scrima, Marianna, Cossu, Alessia Maria, Caraglia, Michele, Misso, Gabriella

“…Exosomes are nanosized vesicles released from all cells into surrounding biofluids, including cancer cells, and represent a very promising direction in terms…”
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Inflammatory Markers and Procalcitonin Predict the Outcome of Metastatic Non-Small-Cell-Lung-Cancer Patients Receiving PD-1/PD-L1 Immune-Checkpoint Blockade by Nardone, Valerio, Giannicola, Rocco, Bianco, Giovanna, Giannarelli, Diana, Tini, Paolo, Pastina, Pierpaolo, Falzea, Antonia Consuelo, Macheda, Sebastiano, Caraglia, Michele, Luce, Amalia, Zappavigna, Silvia, Mutti, Luciano, Pirtoli, Luigi, Giordano, Antonio, Correale, Pierpaolo

“…Peripheral-immune-checkpoint blockade (P-ICB) with mAbs to PD-1 (nivolumab and pembrolizumab) or PD-L1 (atezolizumab, durvalumab, avelumab) alone or…”
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Characterization of KRAS Mutational Regression in Oligometastatic Patients by Ottaiano, Alessandro, de Vera d’Aragona, Roberta Penta, Trotta, Anna Maria, Santorsola, Mariachiara, Napolitano, Maria, Scognamiglio, Giosuè, Tatangelo, Fabiana, Grieco, Paolo, Zappavigna, Silvia, Granata, Vincenza, Perri, Francesco, Luce, Amalia, Savarese, Giovanni, Ianniello, Monica, Casillo, Marika, Petrillo, Nadia, Belli, Andrea, Izzo, Francesco, Nasti, Guglielmo, Caraglia, Michele, Scala, Stefania

“…Background We previously reported rare regressive genetic trajectories of KRAS pathogenic mutations as a specific hallmark of the genuine oligometastatic…”
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Whey Improves In Vitro Endothelial Mitochondrial Function and Metabolic Redox Status in Diabetic State by Martino, Elisa, Luce, Amalia, Balestrieri, Anna, Mele, Luigi, Anastasio, Camilla, D'Onofrio, Nunzia, Balestrieri, Maria Luisa, Campanile, Giuseppe

“…Endothelial dysfunction plays a critical role in the progression of type 2 diabetes mellitus (T2DM), leading to cardiovascular complications. Current…”
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Polydatin Incorporated in Polycaprolactone Nanofibers Improves Osteogenic Differentiation by Lama, Stefania, Luce, Amalia, Bitti, Giuseppe, Chacon-Millan, Pilar, Itro, Annalisa, Ferranti, Pasquale, D’Auria, Giovanni, Cammarota, Marcella, Nicoletti, Giovanni Francesco, Ferraro, Giuseppe Andrea, Schiraldi, Chiara, Caraglia, Michele, Amler, Evzen, Stiuso, Paola

“…Polycaprolactone nanofibers are used as scaffolds in the field of tissue engineering for tissue regeneration or drug delivery. Polycaprolactone (PCL) is a…”
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KRAS Mutational Regression Is Associated With Oligo-Metastatic Status and Good Prognosis in Metastatic Colorectal Cancer by Ottaiano, Alessandro, Nasti, Guglielmo, Santorsola, Mariachiara, Altieri, Vincenzo, Di Fruscio, Giuseppina, Circelli, Luisa, Luce, Amalia, Cossu, Alessia Maria, Scognamiglio, Giosuè, Perri, Francesco, Correra, Marco, Belli, Andrea, Delrio, Paolo, Botti, Gerardo, Caraglia, Michele

“…We previously reported that loss of mutations ("regressive" mutational trajectories) from primary tumors to metastases associated with the oligo-metastatic…”
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miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma by Misso, Gabriella, Zarone, Mayra Rachele, Lombardi, Angela, Grimaldi, Anna, Cossu, Alessia Maria, Ferri, Carmela, Russo, Margherita, Vuoso, Daniela Cristina, Luce, Amalia, Kawasaki, Hiromichi, Di Martino, Maria Teresa, Virgilio, Antonella, Festa, Agostino, Galeone, Aldo, De Rosa, Giuseppe, Irace, Carlo, Donadelli, Massimo, Necas, Alois, Amler, Evzen, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Caraglia, Michele

“…miR-125b, ubiquitously expressed and frequently dysregulated in several tumors, has gained special interest in the field of cancer research, displaying either…”
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Fluorescent nanodiamonds as innovative delivery systems for MiR-34a replacement in breast cancer by Abate, Marianna, Lombardi, Angela, Luce, Amalia, Porru, Manuela, Leonetti, Carlo, Bocchetti, Marco, Campani, Virginia, De Rosa, Giuseppe, Graziano, Sossio Fabio, Nele, Valeria, Cardile, Francesco, Marino, Federica Zito, Franco, Renato, Ronchi, Andrea, Scrima, Marianna, Sperlongano, Rossella, Alfano, Roberto, Misso, Gabriella, Amler, Evzen, Caraglia, Michele, Zappavigna, Silvia

“…Nanodiamonds are innovative nanocrystalline carbon particles able to deliver chemically conjugated miRNAs. In oncology, the use of miRNA-based therapies may…”
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Distinctive germline expression of class I human leukocyte antigen (HLA) alleles and DRB1 heterozygosis predict the outcome of patients with non-small cell lung cancer receiving PD-1/PD-L1 immune checkpoint blockade by Correale, Pierpaolo, Saladino, Rita Emilena, Giannarelli, Diana, Giannicola, Rocco, Agostino, Rita, Staropoli, Nicoletta, Strangio, Alessandra, Del Giudice, Teresa, Nardone, Valerio, Altomonte, Maria, Pastina, Pierpaolo, Tini, Paolo, Falzea, Antonia Consuelo, Imbesi, Natale, Arcati, Valentina, Romeo, Giuseppa, Caracciolo, Daniele, Luce, Amalia, Caraglia, Michele, Giordano, Antonio, Pirtoli, Luigi, Necas, Alois, Amler, Evzen, Barbieri, Vito, Tassone, Pierfrancesco, Tagliaferri, Pierosandro

“…BackgroundNivolumab is a human monoclonal antibody against programmed cell death receptor-1 (PD-1) able to rescue quiescent tumor infiltrating cytotoxic T…”
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Lanreotide Induces Cytokine Modulation in Intestinal Neuroendocrine Tumors and Overcomes Resistance to Everolimus by Sciammarella, Concetta, Luce, Amalia, Riccardi, Ferdinando, Mocerino, Carmela, Modica, Roberta, Berretta, Massimiliano, Misso, Gabriella, Cossu, Alessia Maria, Colao, Annamaria, Vitale, Giovanni, Necas, Alois, Fedacko, Jan, Galdiero, Marilena, Correale, Pierpaolo, Faggiano, Antongiulio, Caraglia, Michele, Capasso, Anna, Grimaldi, Anna

“…Somatostatin analogs mantain their major role in the treatment of patients with advanced neuroendocrine tumors (NETs) and have multiple modulatory effects on…”
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