Search Results - "Lucchi, Laura"
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Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens
Published in Toxicology in vitro (01-08-2009)“…Assessment of allergenic potential of chemicals is performed using animal models, such as the murine local lymph node assay, which does not distinguish between…”
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Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naïve THP-1 cells
Published in Toxicology in vitro (01-03-2008)“…At present, the assessment of the allergenic potential of chemicals is carried out using animal models. Over the last decade, several in vitro methods mainly…”
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High interleukin-10 production is associated with low antibody response to influenza vaccination in the elderly
Published in Journal of leukocyte biology (01-08-2006)“…The present study was designed to determine the correlation among dehydroepiandrosterone (DHEA), cortisol plasma levels, and immune functionality at the time…”
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Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production
Published in Toxicology and applied pharmacology (15-04-2006)“…Mancozeb, a polymeric complex of manganese ethylenebisdithiocarbamate with zinc salt, is widely used in agriculture as fungicide. Literature data indicate that…”
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Protein Kinase C Anchoring Deficit in Postmortem Brains of Alzheimer's Disease Patients
Published in Experimental neurology (01-10-1999)“…Protein kinase C (PKC) has been implicated in the pathophysiology of Alzheimer's disease (AD). The levels of particular isoforms and the activation of PKC are…”
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Age-related decline in RACK-1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone
Published in Journal of leukocyte biology (01-02-2005)“…Aging is associated with remodeling of the immune system, contributing to increased incidence of infections, autoimmune diseases, and cancer among the elderly…”
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A genetic profile of oxytocin receptor improves moral acceptability of outcome-maximizing harm in male insurance brokers
Published in Behavioural brain research (17-08-2020)“…•Male insurance brokers as a sample to study utilitarian attitude.•They are more aligned with utilitarianism than control males.•Frequency of…”
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Protein kinase C activity, translocation, and conventional isoforms in aging rat brain
Published in Neurobiology of aging (01-03-1995)“…Protein kinase C was studied in various brain areas in aging Wistar rats. Histone-directed kinase activity from the cortex, hippocampus and cerebellum did not…”
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Enterodiol and Enterolactone Modulate the Immune Response by Acting on Nuclear Factor-κB (NF-κB) Signaling
Published in Journal of agricultural and food chemistry (09-06-2010)“…Lignan-rich whole-grain cereals, beans, berries, and nuts show protective effects against a variety of chronic diseases, including cancer. Lignans are…”
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Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure
Published in Toxicology and applied pharmacology (15-07-2007)“…Propanil, 3,4-dichloropropionanilide, a commonly used herbicide, has been shown to induce effects on the mouse immune system. The aim of this study was to…”
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Ethanol administration in vivo alters calcium ions control in rat striatum
Published in Brain research (22-04-1985)“…The present paper investigates the effect of chronic ethanol treatment administered through drinking water on [3H]nitrendipine binding and 45Ca uptake in rat…”
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IL-8 release and p38 MAPK activation: Potential tools to classify chemical allergens?
Published in Toxicology letters (13-09-2009)Get full text
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Assessment of the potency of contact allergens by using IL-8 release and p38 MAPK activation in THP-1 cells
Published in Toxicology letters (13-09-2009)Get full text
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Assessment of allergenic potential of low molecular weight compounds based on IL-1alpha and IL-18 production by a human keratinocyte cell line
Published in Toxicology letters (05-10-2008)Get full text
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Role of p38 MAPK in chemical allergen-induced selective production of IL-8 in naïve THP-1 cells
Published in Toxicology letters (01-10-2007)Get full text
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Increased carrageenan‐induced acute lung inflammation in old rats
Published in Immunology (01-06-2005)“…Summary Ageing is associated with increased susceptibility to lung infections and delayed resolution of pulmonary infiltrates. The purpose of this study was to…”
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Effects of ethanol, given during pregnancy, on the offspring dopaminergic system
Published in Pharmacology, biochemistry and behavior (01-10-1983)“…The fetal alcohol syndrome is characterized by a number of abnormalities consisting of a pre- and post-natal growth deficiency, microcephaly, areas of abnormal…”
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A defective protein kinase C anchoring system underlying age-associated impairment in TNF-alpha production in rat macrophages
Published in The Journal of immunology (1950) (15-09-1999)“…The ability of macrophages to secrete cytokines is important in host responses to infections inflammatory stimuli, both of which are altered with aging. In…”
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In Vivo Dehydroepiandrosterone Restores Age-Associated Defects in the Protein Kinase C Signal Transduction Pathway and Related Functional Responses
Published in The Journal of immunology (1950) (15-02-2002)“…Elderly subjects are at increased risk of pneumonia, influenza, and tuberculosis. Besides the known age-related decrease in mechanisms for mechanical clearance…”
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