Search Results - "Lucca Júnior, Waldecy De"
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Abarema cochliacarpos Extract Decreases the Inflammatory Process and Skeletal Muscle Injury Induced by Bothrops leucurus Venom
Published in BioMed research international (01-01-2014)“…Snakebites are a public health problem, especially in tropical countries. However, treatment with antivenom has limited effectiveness against venoms’ local…”
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2
The Ethanol Extract of the Inner Bark of Caesalpinia pyramidalis (Tul.) Reduces Urinary Bladder Damage during Cyclophosphamide-Induced Cystitis in Rats
Published in TheScientificWorld (01-01-2013)“…Hemorrhagic cystitis (HC) is a common side effect of cyclophosphamide therapy, which deserves new therapeutic strategies, such as those based on natural…”
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3
Neuroprotective effect of Portulaca oleracea extracts against 6-hydroxydopamine-induced lesion of dopaminergic neurons
Published in Anais da Academia Brasileira de Ciências (01-09-2016)“…The Portulaca oleracea L. (Portulacaceae) is a cosmopolitan species with a wide range of biological activities, including antioxidant and neuroprotective…”
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4
The anti-hyperalgesic and anti-inflammatory profiles of p-cymene: Evidence for the involvement of opioid system and cytokines
Published in Pharmaceutical biology (01-01-2015)“…Pain corresponds to the most frequent reason for visits to physicians, and its control by conventional drugs is accompanied by several side effects, making…”
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5
Preparation, Characterization, and Pharmacological Activity of Cymbopogon winterianus Jowitt ex Bor (Poaceae) Leaf Essential Oil of β-Cyclodextrin Inclusion Complexes
Published in Evidence-based complementary and alternative medicine (01-01-2015)“…This study aimed to evaluate the orofacial antinociceptive effect of the Cymbopogon winterianus essential oil (LEO) complexed in β-cyclodextrin (LEO-CD) and to…”
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6
Evidence for the involvement of descending pain-inhibitory mechanisms in the attenuation of cancer pain by carvacrol aided through a docking study
Published in Life sciences (1973) (22-10-2014)“…The present study evaluated the carvacrol (CARV) effect on hyperalgesia and nociception induced by sarcoma 180 (S180) in mice. Carvacrol treatment…”
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Citronellol, a natural acyclic monoterpene, attenuates mechanical hyperalgesia response in mice: Evidence of the spinal cord lamina I inhibition
Published in Chemico-biological interactions (05-09-2015)“…•We tested the anti-hyperalgesic and anti-edematogenic effects of citronellol (CT).•CT is able to reduce the mechanical hyperalgesia and paw edema.•CT reduced…”
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8
Cytotoxic activity of essential oil from Leaves of Myrcia splendens against A549 Lung Cancer cells
Published in BMC complementary and alternative medicine (02-05-2023)“…Plants of the Myrcia genus have been widely used in folk medicine to treat various diseases, including cancer. Myrcia splendens species has a diverse chemical…”
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9
Evidence for the involvement of spinal cord-inhibitory and cytokines-modulatory mechanisms in the anti-hyperalgesic effect of hecogenin acetate, a steroidal sapogenin-acetylated, in mice
Published in Molecules (Basel, Switzerland) (19-06-2014)“…Hecogenin is a steroidal sapogenin largely drawn from the plants of the genus Agave, commonly known as 'sisal', and is one of the important precursors used by…”
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10
Neuroprotective and anti-inflammatory effect of pectolinarigenin, a flavonoid from Amazonian Aegiphila integrifolia (Jacq.), against lipopolysaccharide-induced inflammation in astrocytes via NFκB and MAPK pathways
Published in Food and chemical toxicology (01-11-2021)“…Neurodegenerative diseases affect millions of people worldwide. Regardless of the underlying cause, neuroinflammation is the greatest risk factor for…”
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11
Chitosan-functionalized nanostructured lipid carriers containing chloroaluminum phthalocyanine for photodynamic therapy of skin cancer
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2022)“…[Display omitted] •NLC functionalized with chitosan had not yet been investigated in PTD.•Chitosan coating resulted in greater encapsulation efficiency and…”
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12
Anti-proliferative and pro-apoptotic activity of glycosidic derivatives of lawsone in melanoma cancer cell
Published in BMC cancer (02-06-2021)“…Background Melanoma is a malignant cancer that affects melanocytes and is considered the most aggressive skin-type cancer. The prevalence for melanoma cancer…”
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13
In vitro evaluation of the antibacterial effect of Brazilian red propolis ethanol extract in the prevention of periodontal disease in dogs
Published in Comparative immunology, microbiology and infectious diseases (01-01-2023)“…Dental plaque (DP) is found on the surface of teeth and comprises a community of microorganisms that form a structured biofilm. Bacteria present in DP are…”
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14
Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
Published in International journal of morphology (01-03-2012)“…Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has…”
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Effects of the solid lipid nanoparticle of carvacrol on rodents with lung injury from smoke inhalation
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-03-2020)“…The aim of this present study was to evaluate the effect of solid lipid nanoparticles (SLN) containing carvacrol over the lung damage of airway smoke…”
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16
p-Cymene attenuates cancer pain via inhibitory pathways and modulation of calcium currents
Published in Phytomedicine (Stuttgart) (01-08-2019)“…Oncological pain is one of the most prevalent and difficult-to-treat symptoms in patients with cancer. p-Cymene (PC) is a monoterpene found in more than 100…”
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17
Increased Accuracy to c-Fos-Positive Neuron Counting
Published in BioMed research international (2021)“…There is not a described method to count the core label of c-Fos-positive neurons, avoiding false-positive and false-negative results. The aim of this…”
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18
β‐Cyclodextrin‐complexed (−)‐linalool produces antinociceptive effect superior to that of (−)‐linalool in experimental pain protocols
Published in Basic & clinical pharmacology & toxicology (01-09-2013)“…Many plants produce (−)‐linalool, a plant‐derived monoterpene alcohol, including members of the Lamiaceae (mints) and Lauraceae family (laurels, cinnamon,…”
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β‐Cyclodextrin Complex Containing Lippia grata Leaf Essential Oil Reduces Orofacial Nociception in Mice – Evidence of Possible Involvement of Descending Inhibitory Pain Modulation Pathway
Published in Basic & clinical pharmacology & toxicology (01-02-2014)“…The treatment of orofacial pain remains a major challenge for modern medicine. Thus, we prepared and physicochemically characterized a new β‐cyclodextrin…”
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20
Inhibitory effect of O-propargyllawsone in A549 lung adenocarcinoma cells
Published in BMC complementary and alternative medicine (20-09-2023)“…Background Lung cancer is the deadliest type of cancer in the world and the search for compounds that can treat this disease is highly important. Lawsone…”
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