Search Results - "Lucas Sosa"

The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system by Sosa, Lucas J., Cáceres, Alfredo, Dupraz, Sebastián, Oksdath, Mariana, Quiroga, Santiago, Lorenzo, Alfredo

“…The amyloid precursor protein (APP) is a type I transmembrane glycoprotein better known for its participation in the physiopathology of Alzheimer disease as…”
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Sec3 exocyst component knockdown inhibits axonal formation and cortical neuronal migration during brain cortex development by Bustos Plonka, Florentyna, Sosa, Lucas J., Quiroga, Santiago

“…Neurons are the largest known cells, with complex and highly polarized morphologies and consist of a cell body (soma), several dendrites, and a single axon…”
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Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance by Sosa, Lucas J, Bergman, Jared, Estrada-Bernal, Adriana, Glorioso, Thomas J, Kittelson, John M, Pfenninger, Karl H

“…Amyloid precursor protein (APP), a transmembrane glycoprotein, is well known for its involvement in the pathogenesis of Alzheimer disease of the aging brain,…”
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IGF-1 receptor regulates dynamic changes in neuronal polarity during cerebral cortical migration by Nieto Guil, Alvaro F., Oksdath, Mariana, Weiss, Linnea A., Grassi, Diego J., Sosa, Lucas J., Nieto, Marta, Quiroga, Santiago

“…During cortical development, neurons undergo polarization, oriented migration and layer-type differentiation. The biological and biochemical mechanisms…”
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A homemade laboratory applied to the phytoremediation of textile dyes by high school students in the context of the COVID-19 pandemic by Vezza, Mariana E., Sosa Alderete, Lucas G., Agostini, Elizabeth

“…Biosphere contamination is a current environmental and social issue that must be included in the school programme. It is essential that students recognise…”
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LC-ESI-MS/MS Method for the Profiling of Glycerophospholipids and its Application to the Analysis of Tobacco Hairy Roots as Early Indicators of Phenol Pollution by Flor, Sabrina, Sosa Alderete, Lucas, Dobrecky, Cecilia, Tripodi, Valeria, Agostini, Elizabeth, Lucangioli, Silvia

“…The growing impact of organic and inorganic pollutants on the environment has led to the development of numerous strategies to counteract this effect. Among…”
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Functional complexity of the axonal growth cone: a proteomic analysis by Estrada-Bernal, Adriana, Sanford, Staci D, Sosa, Lucas J, Simon, Glenn C, Hansen, Kirk C, Pfenninger, Karl H

“…The growth cone, the tip of the emerging neurite, plays a crucial role in establishing the wiring of the developing nervous system. We performed an extensive…”
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Investigating the Transformation Products of Selected Antibiotics and 17 α-Ethinylestradiol under Three In Vitro Biotransformation Models for Anticipating Their Relevance in Bioaugmented Constructed Wetlands by Alderete, Lucas Sosa, Sauvêtre, Andrés, Chiron, Serge, Tadić, Đorđe

“…The degradation of three antibiotics (sulfamethoxazole, trimethoprim, and ofloxacin) and one synthetic hormone (17 α-ethinylestradiol) was investigated in…”
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Is the PLC pathway involved in the response to phenol treatment in tobacco hairy roots? by Alderete, Lucas G. Sosa, Racagni, Graciela, Agostini, Elizabeth, Medina, María I.

“…Phospholipids and phospholipases play important roles in several cellular processes and responses to adverse growth conditions. However, the mechanism of…”
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The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization by Oksdath, Mariana, Guil, Alvaro F. Nieto, Grassi, Diego, Sosa, Lucas J., Quiroga, Santiago

“…Three early signals of asymmetry have been described to occur in a single neurite of neurons at stage 2 of differentiation (before polarization) and shown to…”
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The TC10-Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons by Dupraz, Sebastian, Grassi, Diego, Bernis, Maria Eugenia, Sosa, Lucas, Bisbal, Mariano, Gastaldi, Laura, Jausoro, Ignacio, Caceres, Alfredo, Pfenninger, Karl H, Quiroga, Santiago

“…Axonal elongation is one of the hallmarks of neuronal polarization. This phenomenon requires axonal membrane growth by exocytosis of plasmalemmal precursor…”
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BARS Influences Neuronal Development by Regulation of Post-Golgi Trafficking by Gastaldi, Laura, Martín, Josefina Inés, Sosa, Lucas Javier, Quassollo, Gonzalo, Peralta Cuasolo, Yael Macarena, Valente, Carmen, Luini, Alberto, Corda, Daniela, Cáceres, Alfredo, Bisbal, Mariano

“…Neurons are highly polarized cells requiring precise regulation of trafficking and targeting of membrane proteins to generate and maintain different and…”
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Protein interacting with NIMA (never in mitosis A)‐1 regulates axonal growth cone adhesion and spreading through myristoylated alanine‐rich C kinase substrate isomerization by Sosa, Lucas J., Malter, James S., Hu, Jie, Bustos Plonka, Florentyna, Oksdath, Mariana, Nieto Guil, Alvaro F., Quiroga, Santiago, Pfenninger, Karl H.

“…Axonal growth cone motility requires precise regulation of adhesion to navigate the complex environment of the nervous system and reach its target…”
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Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome by Sosa, Lucas J., Postma, Nienke L., Estrada‐Bernal, Adriana, Hanna, M., Guo, R., Busciglio, Jorge, Pfenninger, Karl H.

“…Amyloid precursor protein (APP), encoded on Hsa21, functions as a cell adhesion molecule (CAM) in axonal growth cones (GCs) of the developing brain. We show…”
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Increasing knowledge about phytoremediation through a practical approach for undergraduate students by Talano, Melina A., Ibañez, Sabrina, Sosa Alderete, Lucas G., Wevar Oller, Ana L., Vezza, Mariana E., Medina, María I., Agostini, Elizabeth

“…Universities play an important role in society and in providing solutions for its problems. Environmental pollution is one of the most serious problems facing…”
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IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity by Quiroga, Santiago, Sosa, Lucas, Dupraz, Sebastian, Laurino, Lisandro, Bollati, Flavia, Bisbal, Mariano, Cáceres, Alfredo, Pfenninger, Karl H

“…How a neuron becomes polarized remains largely unknown. Results obtained with a function-blocking antibody and an siRNA targeting the insulin-like growth…”
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Phytoremediation of phenol using Vicia sativa L. plants and its antioxidative response by Ibáñez, Sabrina G., Alderete, Lucas G. Sosa, Medina, María I., Agostini, Elizabeth

“…Common vetch ( Vicia sativa L.) is a legume species with an extensive agricultural use. However, the phytoremediation potentiality of this species has not been…”
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Plant growth promoting rhizobacteria improve the antioxidant status in Mentha piperita grown under drought stress leading to an enhancement of plant growth and total phenolic content by Chiappero, Julieta, Cappellari, Lorena del Rosario, Sosa Alderete, Lucas G., Palermo, Tamara B., Banchio, Erika

“…•PGPR inoculation ameliorates drought effects in peppermint plants.•Inoculation with PGPR significantly diminishes the reduction in growth produced by drought…”
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Selected SNARE proteins are essential for the polarized membrane insertion of igf-1 receptor and the regulation of initial axonal outgrowth in neurons by Grassi, Diego, Plonka, Florentyna Bustos, Oksdath, Mariana, Guil, Alvaro Nieto, Sosa, Lucas J, Quiroga, Santiago

“…The establishment of polarity necessitates initial axonal outgrowth and, therefore, the addition of new membrane to the axon’s plasmalemma. Axolemmal expansion…”
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PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone by Laurino, Lisandro, Wang, Xiaoxin X, de la Houssaye, Becky A, Sosa, Lucas, Dupraz, Sebastian, Cáceres, Alfredo, Pfenninger, Karl H, Quiroga, Santiago

“…Exocytotic incorporation of plasmalemmal precursor vesicles (PPVs) into the cell surface is necessary for axonal outgrowth and is known to occur mainly at the…”
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