Search Results - "Lucas, Julie L"

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease by Volkmann, Kori, Lucas, Julie L., Vuga, Danka, Wang, Xiaoping, Brumm, Duane, Stiles, Caryn, Kriebel, David, Der-Sarkissian, Ani, Krishnan, Kris, Schweitzer, Colleen, Liu, Zheng, Malyankar, Uriel M., Chiovitti, David, Canny, Marella, Durocher, Dan, Sicheri, Frank, Patterson, John B.

“…Inositol-requiring enzyme 1 (IRE1) is the most highly conserved signaling node of the unfolded protein response (UPR) and represents a potential therapeutic…”
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Development and validation of a Luminex assay for detection of a predictive biomarker for PROSTVAC-VF therapy by Lucas, Julie L, Tacheny, Erin A, Ferris, Allison, Galusha, Michelle, Srivastava, Apurva K, Ganguly, Aniruddha, Williams, P Mickey, Sachs, Michael C, Thurin, Magdalena, Tricoli, James V, Ricker, Winnie, Gildersleeve, Jeffrey C

“…Cancer therapies can provide substantially improved survival in some patients while other seemingly similar patients receive little or no benefit. Strategies…”
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Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors by Sanches, Mario, Duffy, Nicole M., Talukdar, Manisha, Thevakumaran, Nero, Chiovitti, David, Canny, Marella D., Lee, Kenneth, Kurinov, Igor, Uehling, David, Al-awar, Rima, Poda, Gennadiy, Prakesch, Michael, Wilson, Brian, Tam, Victor, Schweitzer, Colleen, Toro, Andras, Lucas, Julie L., Vuga, Danka, Lehmann, Lynn, Durocher, Daniel, Zeng, Qingping, Patterson, John B., Sicheri, Frank

“…Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a…”
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Induction of Foxp3 + regulatory T cells with histone deacetylase inhibitors by Lucas, Julie L., Mirshahpanah, Parham, Haas-Stapleton, Eric, Asadullah, Khusru, Zollner, Thomas M., Numerof, Robert P.

“…Histone deacetylase inhibitors are under investigation in the clinic as a new class of anti-cancer therapeutics. While recent studies have also suggested their…”
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Calmodulin binding to peptides derived from the i3 loop of muscarinic receptors by LUCAS, Julie L, DANXIN WANG, SADEE, Wolfgang

“…This study was conducted to identify and characterize the structural requirements of a calmodulin-binding motif identified in the third intracellular (i3) loop…”
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Single nucleotide polymorphisms of the human M1 muscarinic acetylcholine receptor gene by Lucas, J L, DeYoung, J A, Sadee, W

“…The gene encoding the human muscarinic receptor, type 1 (CHRM1), was genotyped from 245 samples of the Coriell Collection (Coriell Institute for Medical…”
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Inhibition and Dispersion of Biofilms: Targeting Bacterial Response Regulators to Resensitize Multidrug Resistant Bacteria to Antibiotics by Milton, Morgan E, Draughn, G Logan, Feldmann, Erik A, Thompson, Richele J, Jung, David, Kang, Brian, Theisen, Kelly E, Zeng, Daina, Lucas, Julie L, Melander, Christian C, Cavanagh, John

“…Abstract only Biofilms provide cells with protection against numerous physical and chemical assaults. Bacteria utilize biofilms to avoid antibiotics, leaving…”
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Single Nucleotide Polymorphisms in the Human μ Opioid Receptor Gene Alter Basal G Protein Coupling and Calmodulin Binding by Wang, Danxin, Quillan, J.Mark, Winans, Katharine, Lucas, Julie L., Sadée, Wolfgang

“…The μ opioid receptor (MOR) plays a central role in mediating acute and chronic effects of narcotic drugs. Three rare single nucleotide polymorphisms in the…”
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Single Nucleotide Polymorphisms in the Human μ Opioid Receptor Gene Alter Basal G Protein Coupling and Calmodulin Binding by Danxin Wang, J. Mark Quillan, Katharine Winans, Julie L. Lucas, Wolfgang Sadée

“…The μ opioid receptor (MOR) plays a central role in mediating acute and chronic effects of narcotic drugs. Three rare single nucleotide polymorphisms in the…”
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