Search Results - "Lucas, Erin C"
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Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans
Published in Nucleic acids research (08-01-2019)“…Abstract During haematopoiesis, haematopoietic stem cells differentiate into restricted potential progenitors before maturing into the many lineages required…”
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Cytomegalovirus drives Vδ1+ γδ T cell expansion and clonality in common variable immunodeficiency
Published in Nature communications (20-05-2024)“…The function and phenotype of γδ T cells in the context of common variable immunodeficiency (CVID) has not been explored. CVID is a primary immunodeficiency…”
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Stool Gluten Peptide Detection Is Superior to Urinary Analysis, Coeliac Serology, Dietary Adherence Scores and Symptoms in the Detection of Intermittent Gluten Exposure in Coeliac Disease: A Randomised, Placebo-Controlled, Low-Dose Gluten Challenge Study
Published in Nutrients (01-01-2024)“…Monitoring adherence to a gluten-free diet is an important goal of coeliac disease management. Urine and stool gluten immunogenic peptide (GIP) assays provide…”
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MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms
Published in Oncogenesis (New York, NY) (11-07-2022)“…MiR-21 was identified as a gene whose expression correlated with the extent of metastasis of murine mammary tumours. Since miR-21 is recognised as being…”
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Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer
Published in Cancer immunology research (01-11-2015)“…Metastatic progression is the major cause of breast cancer-related mortality. By examining multiple syngeneic preclinical breast cancer models in mice lacking…”
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Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes
Published in iScience (19-03-2021)“…The proximity pattern and radial distribution of chromosome territories within spherical nuclei are random and non-random, respectively. Whether this…”
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Transcriptional profiling of eosinophil subsets in interleukin‐5 transgenic mice
Published in Journal of leukocyte biology (01-07-2018)“…Eosinophils are important in fighting parasitic infections and are implicated in the pathogenesis of asthma and allergy. IL‐5 is a critical regulator of…”
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Identification of a Siglec‐F+ granulocyte‐macrophage progenitor
Published in Journal of leukocyte biology (01-07-2018)“…In recent years multi‐parameter flow cytometry has enabled identification of cells at major stages in myeloid development; from pluripotent hematopoietic stem…”
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Haemopedia: An Expression Atlas of Murine Hematopoietic Cells
Published in Stem cell reports (13-09-2016)“…Hematopoiesis is a multistage process involving the differentiation of stem and progenitor cells into distinct mature cell lineages. Here we present…”
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