Search Results - "Lucansky Vincent"
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Genetic Heterogeneity, Tumor Microenvironment and Immunotherapy in Triple-Negative Breast Cancer
Published in International journal of molecular sciences (29-11-2022)“…Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological, and molecular levels. Genomic instability and greater mutation…”
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Characterization of Plasmids Isolated from Bacterial Flora of CRC Patients – Proof of Concept
Published in Acta Medica Martiniana (01-04-2024)“…Colorectal cancer (CRC) is one of the leading oncogenic disorders, both in terms of incidence and mortality. The etiology of the disease is certainly…”
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Use of tcdC gene sequencing to prevent misidentification of Clostridioides difficile ribotype 176 and 027
Published in Medicinski glasnik (01-09-2024)“…Aim To compare the sequences of the tcd C gene between Clostridioides difficile (C. difficile ) strains identified as PCR ribotype 176 and the reference strain…”
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Optimizing Droplet Digital PCR Assay for Precise Assessment of MEIS1 Gene Promoter Methylation
Published in Acta Medica Martiniana (01-04-2024)“…DNA methylation is characterized as a gene regulatory mechanism that involves the methylation of the 5-carbon (C5) position of cytosine, resulting in the…”
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The presence of pyruvate carboxylase in the human brain and its role in the survival of cultured human astrocytes
Published in Physiological research (14-07-2023)“…Pyruvate carboxylase (PC) is a mitochondrial, biotin-containing enzyme catalyzing the ATP-dependent synthesis of oxaloacetate from pyruvate and bicarbonate,…”
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Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology
Published in International journal of molecular sciences (27-10-2020)“…Vulvar cancer (VC) is a specific form of malignancy accounting for 5-6% of all gynaecologic malignancies. Although VC occurs most commonly in women after 60…”
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Comparison of the methods for isolation and detection of SARS-CoV-2 RNA in municipal wastewater
Published in Frontiers in public health (07-03-2023)“…Coronavirus SARS-CoV-2 is a causative agent responsible for the current global pandemic situation known as COVID-19. Clinical manifestations of COVID-19…”
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Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus
Published in Nature microbiology (01-07-2019)“…Numerous human APOBEC3 cytidine deaminases have proven to be, inter alia, host cell restriction factors for retroviruses and hepadnaviruses. Although they can…”
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Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells
Published in Clinical & developmental immunology (01-01-2013)“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of…”
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Multi-faceted CRISPR/Cas technological innovation aspects in the framework of 3P medicine
Published in The EPMA journal (01-06-2023)“…Since 2009, the European Association for Predictive, Preventive and Personalised Medicine (EPMA, Brussels) promotes the paradigm change from reactive approach…”
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Targeting monocytic Occludin impairs transendothelial migration and HIV neuroinvasion
Published in EMBO reports (09-08-2024)“…Transmigration of circulating monocytes from the bloodstream to tissues represents an early hallmark of inflammation. This process plays a pivotal role during…”
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Flavonoids attenuate cancer metabolism by modulating Lipid metabolism, amino acids, ketone bodies and redox state mediated by Nrf2
Published in European journal of pharmacology (15-06-2023)“…Metabolic reprogramming of cancer cells is a common hallmark of malignant transformation. The preference for aerobic glycolysis over oxidative phosphorylation…”
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13
LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4 + T lymphocytes
Published in Autophagy (02-08-2024)“…HIV-1 entry into CD4 T lymphocytes relies on the viral and cellular membranes' fusion, leading to viral capsid delivery in the target cell cytoplasm. Atg8/LC3B…”
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Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization
Published in Hepatology (Baltimore, Md.) (01-10-2022)“…Background and Aims Numerous HCV entry factors have been identified, and yet information regarding their spatiotemporal dynamics is still limited…”
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Metabolic Anti-Cancer Effects of Melatonin: Clinically Relevant Prospects
Published in Cancers (16-06-2021)“…Metabolic reprogramming characterized by alterations in nutrient uptake and critical molecular pathways associated with cancer cell metabolism represents a…”
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Comparison of SARS-CoV-2 Detection by Rapid Antigen and by Three Commercial RT-qPCR Tests: A Study from Martin University Hospital in Slovakia
Published in International journal of environmental research and public health (01-07-2021)“…The global pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is having a tremendous…”
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Host genetic variants associated with COVID-19 reconsidered in a Slovak cohort
Published in Advances in medical sciences (01-03-2024)“…We present the results of an association study involving hospitalized coronavirus disease 2019 (COVID-19) patients with a clinical background during the 3rd…”
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Detection of therapeutically relevant and concomitant rare somatic variants in colorectal cancer
Published in Neoplasma (01-11-2021)“…In colorectal cancer (CRC), clinically relevant biomarkers are known for genome-guided therapy that can be detected by both first and next generation methods…”
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Sensitive SARS-CoV-2 detection, air travel Covid-19 testing, variant determination and fast direct PCR detection, using ddPCR and RT-qPCR methods
Published in Acta virologica (Anglickâa verze) (2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monitoring in air traffic is important in the prevention of the virus spreading from abroad. The…”
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Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway
Published in Science advances (08-01-2021)“…The biosynthetic secretory pathway is particularly challenging to investigate as it is underrepresented compared to the abundance of the other intracellular…”
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