Search Results - "Lucaciu, Sergiu A"

Interrogation of Carboxy-Terminus Localized GJA1 Variants Associated with Erythrokeratodermia Variabilis et Progressiva by Lucaciu, Sergiu A, Shao, Qing, Figliuzzi, Rhett, Barr, Kevin, Bai, Donglin, Laird, Dale W

“…Although inherited (encoding Cx43) gene mutations most often lead to oculodentodigital dysplasia and related disorders, four variants have been linked to…”
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GJB4 variants linked to skin disease exhibit a trafficking deficiency en route to gap junction formation that can be restored by co-expression of select connexins by Lucaciu, Sergiu A, Figliuzzi, Rhett, Neumann, Ruth, Nazarali, Samina, Del Sordo, Luigi, Leighton, Stephanie E, Hauser, Alexandra, Shao, Qing, Johnston, Danielle, Bai, Donglin, Laird, Dale W

“…Epidermal keratinocytes are enriched with at least nine connexins that are key regulators of epidermal homeostasis. The role of Cx30.3 in keratinocytes and…”
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Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes by Au, Akina, Shao, Qing, White, Kyra K, Lucaciu, Sergiu A, Esseltine, Jessica L, Barr, Kevin, Laird, Dale W

“…When considering connexin expression and regulation, the epidermis of the skin is one of the most complex tissues found in mammals even though it largely…”
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Diversity in connexin biology by Lucaciu, Sergiu A., Leighton, Stephanie E., Hauser, Alexandra, Yee, Ryan, Laird, Dale W.

“…Over 35 years ago the cell biology community was introduced to connexins as the subunit employed to assemble semicrystalline clusters of intercellular channels…”
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Spatial and Temporal Localization of Connexins in Cells Using Confocal Microscopy by Lucaciu, Sergiu A, Leighton, Stephanie E, Laird, Dale W

“…The 21-member connexin family found in humans is the building block of both single-membrane spanning channels (hemichannels) and double-membrane spanning…”
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Cx31.1 can selectively intermix with co-expressed connexins to facilitate its assembly into gap junctions by Leighton, Stephanie E, Wong, Robert S, Lucaciu, Sergiu A, Hauser, Alexandra, Johnston, Danielle, Stathopulos, Peter B, Bai, Donglin, Penuela, Silvia, Laird, Dale W

“…Connexins are channel-forming proteins that function to facilitate gap junctional intercellular communication. Here, we use dual cell voltage clamp and dye…”
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