Search Results - "Lucía Taja-Chayeb"

DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model by ANTÚNEZ, CARLOS ALBERTO VALENCIA, CHAYEB, LUCÍA TAJA, RODRÍGUEZ-SEGURA, MIGUEL ÁNGEL, ÁLVAREZ, GUADALUPE SOLEDAD LÓPEZ, GARCÍA-CUÉLLAR, CLAUDIA M, TREVIÑO, SAÚL VILLA

“…Carcinogenesis is driven by the accumulation of mutations and abnormal DNA methylation patterns, particularly the hypermethylation of tumor-suppressor genes…”
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Circulating nucleosomes and response to chemotherapy: An in vitro, in vivo and clinical study on cervical cancer patients by Trejo‐Becerril, Catalina, Pérez‐Cárdenas, Enrique, Treviño‐Cuevas, Homero, Taja‐Chayeb, Lucía, García‐López, Patricia, Segura‐Pacheco, Blanca, Chávez‐Blanco, Alma, Lizano‐Soberon, Marcela, González‐Fierro, Aurora, Mariscal, Ignacio, Wegman‐Ostrosky, Talia, Dueñas‐González, Alfonso

“…It is known that cell‐free DNA circulates in plasma/serum of patients with cancer and that part of this DNA circulates as nucleosomes that can be quantified by…”
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Cancer progression mediated by horizontal gene transfer in an in vivo model by Trejo-Becerril, Catalina, Pérez-Cárdenas, Enrique, Taja-Chayeb, Lucía, Anker, Philippe, Herrera-Goepfert, Roberto, Medina-Velázquez, Luis A, Hidalgo-Miranda, Alfredo, Pérez-Montiel, Delia, Chávez-Blanco, Alma, Cruz-Velázquez, Judith, Díaz-Chávez, José, Gaxiola, Miguel, Dueñas-González, Alfonso

“…It is known that cancer progresses by vertical gene transfer, but this paradigm ignores that DNA circulates in higher organisms and that it is biologically…”
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Analysis of the CAG tract length in the Androgen Receptor gene in Mexican patients with nonsyndromic cryptorchidism by Landero-Huerta, Daniel A, Vigueras-Villaseñor, Rosa M, Taja-Chayeb, Lucía, García-Andrade, Fabiola, Aréchaga-Ocampo, Elena, Yokoyama-Rebollar, Emiy, Díaz-Chávez, José, Herrera, Luis A, Chávez-Saldaña, Margarita D

“…Cryptorchidism is the most common genitourinary birth defect in live newborn males and is considered as an important risk factor for testicular germ cell…”
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Landscape of Germline Genetic Variants in AGT, MGMT, and TP53 in Mexican Adult Patients with Astrocytoma by Carlos-Escalante, José Alberto, Gómez-Flores-Ramos, Liliana, Bian, Xiaopeng, Perdomo-Pantoja, Alexander, de Andrade, Kelvin César, Mejía-Pérez, Sonia Iliana, Cacho-Díaz, Bernardo, González-Barrios, Rodrigo, Reynoso-Noverón, Nancy, Soto-Reyes, Ernesto, Sánchez-Correa, Thalía Estefanía, Guerra-Calderas, Lissania, Yan, Chunhua, Chen, Qingrong, Castro-Hernández, Clementina, Vidal-Millán, Silvia, Taja-Chayeb, Lucía, Gutiérrez, Olga, Álvarez-Gómez, Rosa María, Gómez-Amador, Juan Luis, Ostrosky-Wegman, Patricia, Mohar-Betancourt, Alejandro, Herrera-Montalvo, Luis Alonso, Corona, Teresa, Meerzaman, Daoud, Wegman-Ostrosky, Talia

“…Astrocytoma is the most common type of primary brain tumor. The risk factors for astrocytoma are poorly understood; however, germline genetic variants account…”
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Ether à go-go potassium channels as human cervical cancer markers by BARAJAS FARIAS, Luz Maria, BERMUDEZ OCANA, Deysi, HERNANDEZ-GALLEGOS, Elizabeth, CAMACHO-ARROYO, Ignacio, DUENAS-GONZALEZ, Alfonso, PEREZ-CARDENAS, Enrique, PARDO, Luis A, MORALES, Angélica, TAJA-CHAYEB, Lucia, ESCAMILIA, Juan, SANCHEZ-PENA, Carmen, CAMACHO, Javier, DIAZ, Lorenza, LARREA, Fernando, AVILA-CHAVEZ, Euclides, CADENA, Adriana, HINOJOSA, Luz Maria, LARA, Gerardo, VILLANUEVA, Luis Alberto, VARGAS, Carlos

“…Ether a go-go (EAG) potassium channels display oncogenic properties. In normal tissues, EAG mRNA is almost exclusively expressed in brain, but it is expressed…”
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Familial erythrocytosis 2 and von Hippel-Lindau disease in the same pediatric patient by Paulina M. Núñez-Martínez, Lucía Taja-Chayeb, Miguel A. Ramírez-Otero, Verónica Fragoso-Ontiveros, Talia Wegman-Ostrosky, David Cruz-Robles, Silvia Vidal-Millán

“…Background: Patients with familial erythrocytosis type 2 have no increased risk of von Hippel-Lindau-associated tumors, although mutations in the VHL gene…”
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A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes by Zambrano, Pilar, Segura-Pacheco, Blanca, Perez-Cardenas, Enrique, Cetina, Lucely, Revilla-Vazquez, Alma, Taja-Chayeb, Lucía, Chavez-Blanco, Alma, Angeles, Enrique, Cabrera, Gustavo, Sandoval, Karina, Trejo-Becerril, Catalina, Chanona-Vilchis, Jose, Duenas-González, Alfonso

“…The antihypertensive compound hydralazine is a known demethylating agent. This phase I study evaluated the tolerability and its effects upon DNA methylation…”
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Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy by Schcolnik-Cabrera, Alejandro, Chávez-Blanco, Alma, Domínguez-Gómez, Guadalupe, Taja-Chayeb, Lucia, Morales-Barcenas, Rocio, Trejo-Becerril, Catalina, Perez-Cardenas, Enrique, Gonzalez-Fierro, Aurora, Dueñas-González, Alfonso

“…Cancer cells have increased glycolysis and glutaminolysis. Their third feature is increased de novo lipogenesis. As such, fatty acid (FA) synthesis enzymes are…”
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Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines by Chavez-Blanco, Alma, Perez-Plasencia, Carlos, Perez-Cardenas, Enrique, Carrasco-Legleu, Claudia, Rangel-Lopez, Edgar, Segura-Pacheco, Blanca, Taja-Chayeb, Lucia, Trejo-Becerril, Catalina, Gonzalez-Fierro, Aurora, Candelaria, Myrna, Cabrera, Gustavo, Duenas-Gonzalez, Alfonso

“…Among the epigenetic alterations occurring in cancer, DNA hypermethylation and histone hypoacetylation are the focus of intense research because their…”
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NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review by Gutiérrez-Virgen, Jorge E, Piña-Pozas, Maricela, Hernández-Tobías, Esther A, Taja-Chayeb, Lucia, López-González, Ma de Lourdes, Meraz-Ríos, Marco A, Gómez, Rocío

“…Arylamine N-acetyltransferase 2 has been related to drug side effects and cancer susceptibility; its protein structure and acetylation capacity results from…”
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NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review by Jorge E. Gutiérrez-Virgen, Maricela Piña-Pozas, Esther A. Hernández-Tobías, Lucia Taja-Chayeb, Ma. de Lourdes López-González, Marco A. Meraz-Ríos, Rocío Gómez

“…Arylamine N-acetyltransferase 2 has been related to drug side effects and cancer susceptibility; its protein structure and acetylation capacity results from…”
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Expression of platelet derived growth factor family members and the potential role of imatinib mesylate for cervical cancer by Taja-Chayeb, Lucia, Chavez-Blanco, Alma, Martínez-Tlahuel, Jorge, González-Fierro, Aurora, Candelaria, Myrna, Chanona-Vilchis, Jose, Robles, Elizabeth, Dueñas-Gonzalez, Alfonso

“…Despite significant achievements in the treatment of cervical cancer, it is still a deadly disease; hence newer therapeutical modalities are needed…”
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Serum nucleosomes during neoadjuvant chemotherapy in patients with cervical cancer. Predictive and prognostic significance by Trejo-Becerril, Catalina, Oñate-Ocaña, Luis F, Taja-Chayeb, Lucía, Vanoye-Carlo, América, Cetina, Lucely, Duenas-Gonzalez, Alfonso

“…It has been shown that free DNA circulates in serum plasma of patients with cancer and that at least part is present in the form of oligo- and monucleosomes, a…”
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Growth inhibition and transcriptional effects of ribavirin in lymphoma by Dominguez-Gomez, Guadalupe, Cortez-Pedroza, Dominique, Chavez-Blanco, Alma, Taja-Chayeb, Lucia, Hidalgo-Miranda, Alfredo, Cedro-Tanda, Alberto, Beltran-Anaya, Fredy, Diaz-Chavez, Jose, Schcolnik-Cabrera, Alejandro, Gonzalez-Fierro, Aurora, Dueñas-Gonzalez, Alfonso

“…Ribavirin exhibits inhibitory effects on the epigenetic enzyme enhancer of zeste homolog 2 (EZH2), which participates in lymphomagenesis. Additionally,…”
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A Cohort Study of the Prognostic Impact of Exon-16 EZH2 Mutations in a Mexican-Mestizo Population of Patients with Diffuse Large B-Cell Lymphoma by Oñate-Ocaña, Luis F., Ponce-Martínez, Mayra, Taja-Chayeb, Lucia, Gutiérrez-Hernández, Olga, Avilés-Salas, Alejandro, Cantú-de-León, David, Dueñas-González, Alfonso, Candelaria-Hernández, Myrna

“…BACKGROUNDNovel prognostic factors in patients with diffuse large B-cell lymphoma (DLBCL) are required in the era of Rituximab. OBJECTIVEThe objective of the…”
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DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells by Candelaria, Myrna, de la Cruz-Hernandez, Erick, Taja-Chayeb, Lucia, Perez-Cardenas, Enrique, Trejo-Becerril, Catalina, Gonzalez-Fierro, Aurora, Chavez-Blanco, Alma, Soto-Reyes, Ernesto, Dominguez, Guadalupe, Trujillo, Jaenai E, Diaz-Chavez, Jose, Duenas-Gonzalez, Alfonso

“…Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for uptake and metabolic activation of the nucleoside gemcitabine…”
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Antitumor Effects of Systemic DNAse I and Proteases in an In Vivo Model by Trejo-Becerril, Catalina, Pérez-Cardenas, Enrique, Gutiérrez-Díaz, Blanca, De La Cruz-Sigüenza, Desiree, Taja-Chayeb, Lucía, González-Ballesteros, Mauricio, García-López, Patricia, Chanona, José, Dueñas-González, Alfonso

“…Background. Cell-free DNA circulates in cancer patients and induces in vivo cell transformation and cancer progression in susceptible cells. Based on this, we…”
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Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial by Candelaria, Myrna, Herrera, Aquileo, Labardini, Juan, González-Fierro, Aurora, Trejo-Becerril, Catalina, Taja-Chayeb, Lucía, Pérez-Cárdenas, Enrique, de la Cruz-Hernández, Erick, Arias-Bofill, Daymi, Vidal, Silvia, Cervera, Eduardo, Dueñas-Gonzalez, Alfonso

“…Decitabine and azacitidine, two DNA methyltransferase (DNMT) inhibitors, are the current standard of treatment for myelodysplastic syndrome (MDS). Histone…”
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A combination of inhibitors of glycolysis, glutaminolysis and de novo fatty acid synthesis decrease the expression of chemokines in human colon cancer cells by Schcolnik-Cabrera, Alejandro, Dominguez-Gómez, Guadalupe, Chávez-Blanco, Alma, Ramírez-Yautentzi, Marisol, Morales-Bárcenas, Rocío, Chávez-Díaz, José, Taja-Chayeb, Lucía, Dueáas-González, Alfonso

“…Lonidamine, 6-Diazo-5-oxo-L-norleucine (DON) and orlistat are well known inhibitors of glycolysis, glutaminolysis and of fatty acid synthesis, respectively…”
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