Search Results - "Luboshits, Galia"

Quantification of Drug Release Degree In Vivo Using Antibody-Guided, Dual-NIR-Dye Ratiometric System by Thankarajan, Ebaston, Jadhav, Suchita, Luboshits, Galia, Gellerman, Gary, Patsenker, Leonid

“…Fluorescent dyes linked to drug delivery systems provide important real-time information on the efficacy of drug delivery. However, the quantitative monitoring…”
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Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells by Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A

“…Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the…”
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Experimental Validation of a Mathematical Model to Describe the Drug Cytotoxicity of Leukemic Cells by Guzev, Ekaterina, Luboshits, Galia, Bunimovich-Mendrazitsky, Svetlana, Firer, Michael A.

“…Chlorambucil (Chl), Melphalan (Mel), and Cytarabine (Cyt) are recognized drugs used in the chemotherapy of patients with advanced Chronic Lymphocytic Leukemia…”
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Antibody‐Drug‐Conjugate Therapy for Hematological Cancers: Matching Cell Biology with Clinical Benefit by Firer, Michael A., Luboshits, Galia

“…Progress in the development and clinical efficacy of antibody‐drug conjugates (ADCs) has attracted the interests of both academic researchers and the industry…”
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Tracking the cellular immune response from early premalignancy to active multiple myeloma in a new model by Jadhav, Suchita Suryakant, Luboshits, Galia, Bogen, Bjarne, Firer, Michael A.

“…To calibrate a murine model to study premalignant to malignant multiple myeloma, mice were inoculated with different amounts of myeloma cells, and changes in…”
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A New Cellular Immunotherapy for the Treatment of Multiple Myeloma without Development of Graft-Versus-Host Disease by Firer, Michael A, Yado, Sofi, Galia, Luboshits, Or, Reuven

“…Multiple myeloma (MM) is a malignant plasma cell disorder that accounts for approximately 10% of all hematological cancers. Despite recent advances, long-term…”
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The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+ CD25+ T cells by Mausner-Fainberg, Karin, Luboshits, Galia, Mor, Adi, Maysel-Auslender, Sophia, Rubinstein, Ardon, Keren, Gad, George, Jacob

“…Abstract Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) are in widespread use due to their LDL reducing properties and…”
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Role of Naturally Occurring CD4+CD25+ Regulatory T Cells in Experimental Atherosclerosis by Mor, Adi, Planer, David, Luboshits, Galia, Afek, Arnon, Metzger, Shula, Chajek-Shaul, Tova, Keren, Gad, George, Jacob

“…OBJECTIVE—Naturally occurring CD4CD25 regulatory T cells (Tregs) exert suppressive effects on effector CD4 cells and downregulate experimental autoimmune…”
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The effects of stress and transcranial direct current stimulation (tDCS) on working memory: A randomized controlled trial by Ankri, Yael L.E., Braw, Yoram, Luboshits, Galia, Meiron, Oded

“…Recent reviews of transcranial direct current stimulation (tDCS) show limited support for its initially cited enhancing effects on working memory (WM). They…”
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Altered status of CD4(+)CD25(+) regulatory T cells in patients with acute coronary syndromes by Mor, Adi, Luboshits, Galia, Planer, David, Keren, Gad, George, Jacob

“…Considerable evidence supports the role of innate and adaptive immunity in the progression and destabilization of the atheromatous plaque. Naturally occurring…”
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The Impact of Induction Regimes on Immune Responses in Patients with Multiple Myeloma by Firer, Michael A, Shapira, Michael Y, Luboshits, Galia

“…Current standard frontline therapy for newly diagnosed patients with multiple myeloma (NDMM) involves induction therapy, autologous stem cell transplantation…”
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Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma by Redko, Boris, Tuchinsky, Helena, Segal, Tamar, Tobi, Dror, Luboshits, Galia, Ashur-Fabian, Osnat, Pinhasov, Albert, Gerlitz, Gabi, Gellerman, Gary

“…The newly discovered short (9 amino acid) non-RGD S-S bridged cyclic peptide ALOS-4 (H-cycl(Cys-Ser-Ser-Ala-Gly-Ser-Leu-Phe-Cys)-OH), which binds to integrin…”
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Effect of toluene on Pseudomonas stutzeri ST-9 morphology - plasmolysis, cell size, and formation of outer membrane vesicles by Michael, Esti, Nitzan, Yeshayahu, Langzam, Yakov, Luboshits, Galia, Cahan, Rivka

“…Isolated toluene-degrading Pseudomonas stutzeri ST-9 bacteria were grown in a minimal medium containing toluene (100 mg·L(-1)) (MMT) or glucose (MMG) as the…”
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Exosomes as biomarkers for identification quantitation and stratification of chronic lymphocytic leukaemia by Cohen, Sapir, Luboshits, Galia, Firer, Michael A

“…Background: CLL is most common type of adult leukemia, molecular and clinically heterogeneous disease. CLL clinical staging is commonly made according to the…”
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Abstract A85: Peptides specific for chronic lymphocytic leukemic cells: Characterization and use in targeted drug delivery by Firer, Michael A., Lubin, Bat-Chen, Cohen, Sharon, Luboshits, Galia

“…Abstract The ability to selectively target drugs to Chronic Lymphocytic Leukemia (CLL) cells may significantly improve the efficacy of current chemotherapy…”
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The CC chemokine RANTES in breast carcinoma progression: Regulation of expression and potential mechanisms of promalignant activity by AZENSHTEIN, Elina, LUBOSHITS, Galia, SHINA, Sima, NEUMARK, Eran, SHAHBAZIAN, David, WEIL, Miguel, WIGLER, Nely, KEYDAR, Iafa, BEN-BARUCH, Adit

“…Breast cancer progression may be affected by various cellular components expressed by the tumor cells and/or by microenvironmental factors. Many studies report…”
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Drug resistance to chlorambucil in murine B-cell leukemic cells is overcome by its conjugation to a targeting peptide by Gellerman, Gary, Baskin, Sophia, Galia, Luboshits, Gilad, Yosef, Firer, Michael A

“…Targeting drugs through small-molecule carriers with a high affinity to receptors on cancer cells can overcome the lack of target cell specificity of most…”
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Erythropoietin improves myocardial performance in doxorubicin-induced cardiomyopathy by Hamed, Saher, Barshack, Iris, Luboshits, Galia, Wexler, Dov, Deutsch, Varda, Keren, Gad, George, Jacob

“…Doxorubicin (Dox) is a potent chemotherapeutic agent associated with severe cardiotoxicity. Erythropoietin (Epo) has recently been shown to exhibit…”
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Elevated expression of the CC chemokine Regulated on activation, normal T Cell Expressed and Secreted (RANTES) in advanced breast carcinoma by LUBOSHITS, G, SHINA, S, KAPLAN, O, ENGELBERG, S, NASS, D, LIFSHITZ-MERCER, B, CHAITCHIK, S, KEYDAR, I, BEN-BARUCH, A

“…Breast carcinoma is the most common malignant disease among women and the second most lethal one. In search for a better understanding of the role of cellular…”
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Constitutive Expression of HIF‐1α and HIF‐2α in Bone Marrow Stromal Cells Differentially Promotes Their Proangiogenic Properties by Ben‐Shoshan, Jeremy, Schwartz, Shulamit, Luboshits, Galia, Maysel‐Auslender, Sofia, Barzelay, Aya, Polak‐Charcon, Sylvie, Tzahor, Eldad, Barshack, Iris, Barak, Adiel, Levkovitch‐Verbin, Hani, Keren, Gad, George, Jacob

“…Bone marrow stromal cells (BMSCs) contain progenitors capable of participating in postnatal angiogenesis. Hypoxia‐inducible factors (HIFs) mediate endothelial…”
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