Search Results - "Lubega, George W"

Theileria parva genetic diversity and haemoparasite prevalence in cattle and wildlife in and around Lake Mburo National Park in Uganda by Oura, Chris A. L., Tait, Andy, Asiimwe, Benon, Lubega, George W., Weir, William

“…Wildlife, especially Cape buffalo ( Syncerus caffer ), are thought to act as a reservoir for many of the important tick-borne pathogens of cattle. In this…”
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Nucleic Acid Sequence-Based Amplification with Oligochromatography for Detection of Trypanosoma brucei in Clinical Samples by Mugasa, Claire M, Laurent, Thierry, Schoone, Gerard J, Kager, Piet A, Lubega, George W, Schallig, Henk D.F.H

“…Molecular tools, such as real-time nucleic acid sequence-based amplification (NASBA) and PCR, have been developed to detect Trypanosoma brucei parasites in…”
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The emergence of Taenia solium cysticercosis in Eastern and Southern Africa as a serious agricultural problem and public health risk by Phiri, Isaac K., Ngowi, Helena, Afonso, Sonia, Matenga, Elizabeth, Boa, Mathias, Mukaratirwa, Samson, Githigia, Samuel, Saimo, Margaret, Sikasunge, Chummy, Maingi, Ndichu, Lubega, George W., Kassuku, Ayub, Michael, Lynne, Siziya, Seter, Krecek, Rosina C., Noormahomed, Emilia, Vilhena, Manuela, Dorny, Pierre, Lee Willingham III, A.

“…Pig production has increased significantly in the Eastern and Southern Africa (ESA) region during the past decade, especially in rural, resource-poor,…”
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Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and Uganda by Matovu, Enock, Mugasa, Claire M, Ekangu, Rosine Ali, Deborggraeve, Stijn, Lubega, George W, Laurent, Thierry, Schoone, Gerard J, Schallig, Henk D, Büscher, Philippe

“…The polymerase chain reaction (PCR) and nucleic acid sequence-based amplification (NASBA) have been recently modified by coupling to oligochromatography (OC)…”
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Effect of adjuvants on the humoral immune response to congopain in mice and cattle by Kateregga, John, Lubega, George W, Lindblad, Erik B, Authié, Edith, Coetzer, Theresa Helen Taillefer, Boulangé, Alain François Vincent

“…We investigated several adjuvants for their effects on the humoral immune response in both mice and cattle using the central domain of congopain (C2), the…”
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Trypanosoma brucei brucei traverses different biological barriers differently and may modify the host plasma membrane in the process by Namayanja, Monica, Dai, Yan, Nerima, Barbara, Matovu, Enock, Lun, Zhao-Rong, Lubega, George W., Zhengjun, Chen

“…Trypanosoma brucei are extracellular hemoflagellate protozoan parasites and one of the causative agents of a devastating zoonotic disease called African…”
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Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south‐western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci by Nanteza, Anne, Obara, Isaiah, Kasaija, Paul, Mwega, Elisa, Kabi, Fredrick, Salih, Diaeldin A., Njahira, Moses, Njuguna, Joyce, Odongo, David, Bishop, Richard P., Skilton, Rob A., Ahmed, Jabbar, Clausen, Peter‐Henning, Lubega, George W.

“…Theileria parva is a tick‐transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a…”
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Transmitted Antiretroviral Drug Resistance Among Drug-Naive Female Sex Workers With Recent Infection in Kampala, Uganda by Ssemwanga, Deogratius, Ndembi, Nicaise, Lyagoba, Frederick, Magambo, Brian, Kapaata, Anne, Bukenya, Justine, Lubega, George W., Bertagnolio, Silvia, Vandepitte, Judith, Grosskurth, Heiner, Kaleebu, Pontiano

“…During 2006—2007, transmitted human immunodeficiency virus (HIV) drug resistance (TDR) among drug-naive women with newly diagnosed HIV infection and likely to…”
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Comparison of nucleic acid sequence-based amplification and loop-mediated isothermal amplification for diagnosis of human African trypanosomiasis by Mugasa, Claire M, Katiti, Diana, Boobo, Alex, Lubega, George W, Schallig, Henk D.F.H, Matovu, Enock

“…Abstract Diagnosis of human African trypanosomiasis (HAT) using molecular tests should ideally achieve high sensitivity without compromising specificity. This…”
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Identification of coding sequences from a freshly prepared Trypanosoma brucei brucei expression library by polymerase chain reaction by Okalang, Uthman, Nanteza, Ann, Matovu, Enock, Lubega, George W

“…Animal African trypanosomiasis (AAT) also known as Nagana is a devastating disease among domestic animals in large parts of Sub-Saharan Africa causing loses in…”
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Accordance and concordance of PCR and NASBA followed by oligochromatography for the molecular diagnosis of Trypanosoma brucei and Leishmania by Mugasa, Claire M, Deborggraeve, Stijn, Schoone, Gerard J, Laurent, Thierry, Leeflang, Mariska M, Ekangu, Rosine A, El Safi, Sayda, Saad, Al-farazdag A, Basiye, Frank L, De Doncker, Simone, Lubega, George W, Kager, Piet A, Büscher, Philippe, Schallig, Henk D.F.H

“…To evaluate the repeatability and reproducibility of four simplified molecular assays for the diagnosis of Trypanosoma brucei spp. or Leishmania ssp. in a…”
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Detection of Trypanosoma brucei parasites in blood samples using real-time nucleic acid sequence-based amplification by Mugasa, Claire M, Schoone, Gerard J, Ekangu, Rosine A, Lubega, George W, Kager, Piet A, Schallig, Henk D.F.H

“…Abstract Currently, the conventional diagnosis of human African trypanosomiasis (HAT) is by microscopic demonstration of trypomastigotes in blood, lymph,…”
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Detection of mutant P2 adenosine transporter (TbAT1) gene in Trypanosoma brucei gambiense isolates from northwest Uganda using allele-specific polymerase chain reaction by Nerima, Barbara, Matovu, Enock, Lubega, George W, Enyaru, John C.K

“…To assess the application of allele-specific PCR (AS-PCR) as a fast, cheap and reliable method for detecting mutant TbAT1 associated with melarsoprol relapse…”
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Classical ligands interact with native and recombinant tubulin from Onchocerca volvulus with similar rank order of magnitude by Wampande, Eddie M., Richard McIntosh, J., Lubega, George W.

“…The α- and β-tubulin genes from Onchocerca volvulus were individually expressed for the first time in Escherichia coli (DH5α). The recombinant tubulins were…”
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Immunization with a tubulin-rich preparation from Trypanosoma brucei confers broad protection against African trypanosomosis by Lubega, George W., Byarugaba, Denis K., Prichard, Roger K.

“…Tubulin from Trypanosoma brucei was purified to near homogeneity using a protocol which involved treatment with urea with subsequent renaturation and was then…”
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CLASSICAL LIGANDS BIND TUBULIN OF TRYPANOSOMES AND INHIBIT THEIR GROWTH IN VITRO by Ochola, Donasian O. K, Prichard, Roger K, Lubega, George W

“…Tubulin ligands known to be toxic to certain organisms or cells were tested for their ability to inhibit proliferation of trypanosomes in culture. Tubulin was…”
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Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substrates by Buckner, Frederick S, Kateete, David P, Lubega, George W, Van Voorhis, Wesley C, Yokoyama, Kohei

“…Carboxyl methylation of the C-terminal prenylated cysteine, which occurs in most farnesylated and geranylgeranylated proteins, is a reversible step and is…”
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Trypanosoma brucei: anti-tubulin antibodies specifically inhibit trypanosome growth in culture by Lubega, George W., Ochola, Donosian O.K., Prichard, Roger K.

“…We previously observed that trypanosome tubulin immunizes mice against infection by this parasite. Here we describe the direct effect of anti-tubulin…”
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Transmitted Antiretroviral Drug Resistance Among Drug-Naive Female Sex Workers With Recent Infection in Kampala, Uganda: The World Health Organization HIV Drug Resistance Prevention and Assessment Strategy: Global, Regional, and Country Progress by SSEMWANGA, Deogratius, NDEMBI, Nicaise, KALEEBU, Pontiano, LYAGOBA, Frederick, MAGAMBO, Brian, KAPAATA, Anne, BUKENYA, Justine, LUBEGA, George W, BERTAGNOLIO, Silvia, VANDEPITTE, Judith, GROSSKURTH, Heiner

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Identification of Trypanosoma vivax subtypes isolated from cattle and goats using microsatellite markers/Identifikacija podtipova protozoona Trypanosoma vivax izdvojenih iz goveda i koza pomocu mikrosatelitskih markera by Biryomumaisho, Savino, Katunguka-Rwakishaya, Eli, Lubega, George W, Melville, Sara E

“…Microsatellite DNA polymorphisms can be utilised to assess intra-specific genetic diversity and hence are useful for characterisation of species and strains of…”
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