Search Results - "Lubahn, DB"

Estrogen receptor specificity for the effects of estrogen in ovariectomized mice by Lindberg, MK, Weihua, Z, Andersson, N, Moverare, S, Gao, H, Vidal, O, Erlandsson, M, Windahl, S, Andersson, G, Lubahn, DB, Carlsten, H, Dahlman-Wright, K, Gustafsson, JA, Ohlsson, C

“…Estrogen exerts a variety of important physiological effects, which have been suggested to be mediated via the two known estrogen receptors (ERs), alpha and…”
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Intraovarian actions of oestrogen by Rosenfeld, CS, Wagner, JS, Roberts, RM, Lubahn, DB

“…Oestrogen regulates several hypothalamic and pituitary hormones, which in turn control ovarian functions. Oestrogen and its metabolites, such as…”
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Analysis of temporal changes in the expression of estrogen-regulated genes in the uterus by Watanabe, H, Suzuki, A, Kobayashi, M, Takahashi, E, Itamoto, M, Lubahn, DB, Handa, H, Iguchi, T

“…In order to understand early events caused by estrogen in vivo, temporal uterine gene expression profiles at early stages were examined using DNA microarray…”
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Tissue-specific estrogenic and non-estrogenic effects of a xenoestrogen, nonylphenol by Watanabe, H, Suzuki, A, Goto, M, Lubahn, DB, Handa, H, Iguchi, T

“…Alkylphenols perturb the endocrine system and are considered to have weak estrogenic activities. Although it is known that nonylphenol can bind weakly to the…”
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Similarities and differences in uterine gene expression patterns caused by treatment with physiological and non-physiological estrogens by Watanabe, H, Suzuki, A, Kobayashi, M, Lubahn, DB, Handa, H, Iguchi, T

“…Administration of physiological and non-physiological estrogens during pregnancy or after birth is known to have adverse effects on the development of the…”
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Increased Adipose Tissue in Male and Female Estrogen receptor-α Knockout Mice by Heine, P. A., Taylor, J. A., Iwamoto, G. A., Lubahn, D. B., Cooke, P. S.

“…Estrogen regulates the amount of white adipose tissue (WAT) in females, but its role in males and whether WAT effects involve estrogen receptor-α (ERα ) or ERβ…”
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The Soy Isoflavone Genistein Decreases Adipose Deposition in Mice by Naaz, Afia, Yellayi, Srikanth, Zakroczymski, Melissa A, Bunick, David, Doerge, Daniel R, Lubahn, Dennis B, Helferich, William G, Cooke, Paul S

“…Adipose tissue is responsive to estrogen and expresses both estrogen receptor α and β. To test the hypothesis that the estrogenic soy isoflavone genistein can…”
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Estrogen Receptor α (ERα) Deficiency in Macrophages Results in Increased Stimulation of CD4+ T Cells while 17β-Estradiol Acts through ERα to Increase IL-4 and GATA-3 Expression in CD4+ T Cells Independent of Antigen Presentation by Lambert, K. Chad, Curran, Edward M., Judy, Barbara M., Milligan, Gregg N., Lubahn, Dennis B., Estes, D. Mark

“…Abstract The effects of 17β-estradiol (E2) on immune function have been extensively reported. The effects are dependent on concentration and duration of…”
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Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease by Liu, Hong-biao, Loo, Kyi Kyi, Palaszynski, Karen, Ashouri, Judith, Lubahn, Dennis B, Voskuhl, Rhonda R

“…Estrogens are known to influence a variety of autoimmune diseases, but it is not known whether their actions are mediated through classic estrogen receptor…”
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Roles of estrogen receptor-alpha gene expression in reproduction-related behaviors in female mice by Ogawa, S, Eng, V, Taylor, J, Lubahn, D B, Korach, K S, Pfaff, D W

“…The role of gene expression of the estrogen receptor-alpha form (ER alpha) in the regulation of female reproductive behavior was investigated in estrogen…”
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Estrogen Receptor Specificity in the Regulation of Skeletal Growth and Maturation in Male Mice by Vidal, Olle, Lindberg, Marie K., Hollberg, Karin, Baylink, David J., Andersson, Goran, Lubahn, Dennis B., Mohan, Subburaman, Gustafsson, Jan-Ake, Ohlsson, Claes

“…Androgens may regulate the male skeleton directly through a stimulation of androgen receptors or indirectly through aromatization of androgens into estrogen…”
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A role for oestrogens in the male reproductive system by Hess, Rex A, Bunick, David, Lee, Ki-Ho, Bahr, Janice, Taylor, Julia A, Korach, Kenneth S, Lubahn, Dennis B

“…Oestrogen is considered to be the 'female' hormone, whereas testosterone is considered the 'male' hormone. However, both hormones are present in both sexes…”
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Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility by Eddy, E M, Washburn, T F, Bunch, D O, Goulding, E H, Gladen, B C, Lubahn, D B, Korach, K S

“…The reproductive system of male mice homozygous for a mutation in the estrogen receptor (ER) gene (ER knock-out; ERKO) appears normal at the anatomical level…”
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Genistein alters methylation patterns in mice by Day, J Kevin, Bauer, Andrew M, DesBordes, Charles, Zhuang, Yi, Kim, Byung-Eun, Newton, Leslie G, Nehra, Vedika, Forsee, Kara M, MacDonald, Ruth S, Besch-Williford, Cynthia, Huang, Tim Hui-Ming, Lubahn, Dennis B

“…In this study we examine the effect of the phytoestrogen genistein on DNA methylation. DNA methylation is thought to inhibit transcription of genes by…”
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Modifications of testosterone-dependent behaviors by estrogen receptor-alpha gene disruption in male mice by Ogawa, S, Washburn, T F, Taylor, J, Lubahn, D B, Korach, K S, Pfaff, D W

“…The role of the a form of estrogen receptor (ER alpha) gene expression in the regulation of testosterone-dependent male reproductive behaviors was investigated…”
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Behavioral Effects of Estrogen Receptor Gene Disruption in Male Mice by Ogawa, Sonoko, Lubahn, Dennis B., Korach, Kenneth S., Pfaff, Donald W.

“…Gonadal steroid hormones regulate sexually dimorphic development of brain functions and behaviors. Their nuclear receptors offer the opportunity to relate…”
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Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult by Schomberg, D W, Couse, J F, Mukherjee, A, Lubahn, D B, Sar, M, Mayo, K E, Korach, K S

“…Targeted disruption of the mouse estrogen receptor-alpha gene (estrogen receptor-alpha knockout; ERKO) results in a highly novel ovarian phenotype in the…”
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Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man by Smith, Eric P, Boyd, Jeff, Frank, Graeme R, Takahashi, Hiroyuki, Cohen, Robert M, Specker, Bonny, Williams, Timothy C, Lubahn, Dennis B, Korach, Kenneth S

“…The actions of adrenal and gonadal steroids, thyroid hormone, and vitamin D are mediated by receptors encoded by a family of related genes. Mutations of…”
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Estrogen Receptor-α Gene Deficiency Enhances Androgen Biosynthesis in the Mouse Leydig Cell by Akingbemi, Benson T, Ge, Renshan, Rosenfeld, Cheryl S, Newton, Leslie G, Hardy, Dianne O, Catterall, James F, Lubahn, Dennis B, Korach, Kenneth S, Hardy, Matthew P

“…Leydig cells, which produce the primary male steroid hormone testosterone (T), express the two estrogen receptor (ER) subtypes, ERα and ERβ, and have the…”
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Stromal Estrogen Receptors Mediate Mitogenic Effects of Estradiol on Uterine Epithelium by Cooke, P. S., Buchanan, D. L., Young, P., Setiawan, T., Brody, J., Korach, K. S., Taylor, J., Lubahn, D. B., Cunha, G. R.

“…Estradiol-17 β (E2) acts through the estrogen receptor (ER) to regulate uterine growth and functional differentiation. To determine whether E2 elicits…”
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