Search Results - "Luan Phan, K"

The contextual brain: implications for fear conditioning, extinction and psychopathology by Maren, Stephen, Phan, K. Luan, Liberzon, Israel

“…Key Points Contexts provide information that is central to understanding the meaning of events. Studies of associative learning, including Pavlovian fear…”
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Effects of childhood poverty and chronic stress on emotion regulatory brain function in adulthood by Kim, Pilyoung, Evans, Gary W., Angstadt, Michael, Ho, S. Shaun, Sripada, Chandra S., Swain, James E., Liberzon, Israel, Phan, K. Luan

“…Childhood poverty has pervasive negative physical and psychological health sequelae in adulthood. Exposure to chronic stressors may be one underlying mechanism…”
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ABERRANT AMYGDALA-FRONTAL CORTEX CONNECTIVITY DURING PERCEPTION OF FEARFUL FACES AND AT REST IN GENERALIZED SOCIAL ANXIETY DISORDER by Prater, Katherine E., Hosanagar, Avinash, Klumpp, Heide, Angstadt, Mike, Luan Phan, K.

“…Background Generalized social anxiety disorder (gSAD) is characterized by exaggerated amygdala reactivity to social signals of threat, but if and how the…”
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Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder by LABUSCHAGNE, Izelle, LUAN PHAN, K, WOOD, Amanda, ANGSTADT, Mike, CHUA, Phyllis, HEINRICHS, Markus, STOUT, Julie C, NATHAN, Pradeep J

“…Patients with generalized social anxiety disorder (GSAD) exhibit heightened activation of the amygdala in response to social cues conveying threat (eg,…”
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Orexin modulation of stress reactivity as a novel targeted treatment for anxiety and alcohol use disorder by Gorka, Stephanie M, Phan, K Luan

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Cannabinoid modulation of prefrontal–limbic activation during fear extinction learning and recall in humans by Rabinak, Christine A., Angstadt, Mike, Lyons, Maryssa, Mori, Shoko, Milad, Mohammed R., Liberzon, Israel, Luan Phan, K.

“…•Δ9-tetrahydrocannabinol (THC) increased vmPFC and HIPP activation during extinction memory recall (vs. placebo).•THC attenuated amygdala activity during early…”
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Insula reactivity and connectivity to anterior cingulate cortex when processing threat in generalized social anxiety disorder by Klumpp, Heide, Angstadt, Mike, Phan, K. Luan

“…► There is evidence of exaggerated insula reactivity to threat in social anxiety. ► Aberrant insula–prefrontal interactions may underlie social anxiety. ► We…”
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Neural reactivity to affective stimuli and internalizing symptom dimensions in a transdiagnostic patient sample by Granros, Maria, MacNamara, Annmarie, Klumpp, Heide, Phan, K. Luan, Burkhouse, Katie L.

“…Background Internalizing psychopathologies (IPs) are highly comorbid and exhibit substantial overlap, such as aberrant affective reactivity. Neural reactivity…”
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Age-related changes in amygdala-frontal connectivity during emotional face processing from childhood into young adulthood by Wu, Minjie, Kujawa, Autumn, Lu, Lisa H., Fitzgerald, Daniel A., Klumpp, Heide, Fitzgerald, Kate D., Monk, Christopher S., Phan, K. Luan

“…The ability to process and respond to emotional facial expressions is a critical skill for healthy social and emotional development. There has been growing…”
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Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol by Weafer, Jessica, Gorka, Stephanie M, Dzemidzic, Mario, Kareken, David A, Phan, K Luan, de Wit, Harriet

“…Poor inhibitory control and heightened feelings of stimulation after alcohol are two well-established risk factors for alcohol use disorder (AUD). Although…”
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Oxytocin modulation of amygdala functional connectivity to fearful faces in generalized social anxiety disorder by Gorka, Stephanie M, Fitzgerald, Daniel A, Labuschagne, Izelle, Hosanagar, Avinash, Wood, Amanda G, Nathan, Pradeep J, Phan, K Luan

“…The neuropeptide oxytocin (OXT) is thought to attenuate anxiety by dampening amygdala reactivity to threat in individuals with generalized social anxiety…”
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Amygdala and Orbitofrontal Reactivity to Social Threat in Individuals with Impulsive Aggression by Coccaro, Emil F, McCloskey, Michael S, Fitzgerald, Daniel A, Phan, K. Luan

“…Background Converging evidence from animal and human lesion studies implicates the amygdala and orbitofrontal cortex (OFC) in emotional regulation and…”
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The neural correlates of intertemporal decision-making: Contributions of subjective value, stimulus type, and trait impulsivity by Sripada, Chandra Sekhar, Gonzalez, Richard, Luan Phan, K., Liberzon, Israel

“…Making choices between payoffs available at different points in time reliably engages a decision‐making brain circuit that includes medial prefrontal cortex…”
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Acquisition of CS-US contingencies during Pavlovian fear conditioning and extinction in social anxiety disorder and posttraumatic stress disorder by Rabinak, Christine A, Mori, Shoko, Lyons, Maryssa, Milad, Mohammed R, Phan, K. Luan

“…Abstract Background Fear-based disorders, like social anxiety disorder (SAD) and posttraumatic stress disorder (PTSD), are characterized by an exaggerated fear…”
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Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder by Klumpp, Heide, Fitzgerald, Daniel A., Phan, K. Luan

“…Cognitive behavioral therapy (CBT) is “gold standard” psychotherapy for social anxiety disorder (SAD). Cognitive models posit that preferential processing of…”
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Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial by Gorka, Stephanie M, Young, Christina B, Klumpp, Heide, Kennedy, Amy E, Francis, Jennifer, Ajilore, Olusola, Langenecker, Scott A, Shankman, Stewart A, Craske, Michelle G, Stein, Murray B, Phan, K Luan

“…Mechanisms and predictors for the successful treatment of anxiety and depression have been elusive, limiting the effectiveness of existing treatments and…”
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Modulation of Resting-State Amygdala-Frontal Functional Connectivity by Oxytocin in Generalized Social Anxiety Disorder by DODHIA, Sonam, HOSANAGAR, Avinash, FITZGERALD, Daniel A, LABUSCHAGNE, Izelle, WOOD, Amanda G, NATHAN, Pradeep J, PHAN, K. Luan

“…Generalized social anxiety disorder (GSAD) is characterized by aberrant patterns of amygdala-frontal connectivity to social signals of threat and at rest. The…”
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Neuronal responses to adverse social threat in healthy human subjects by Coccaro, Emil F., Keedy, Sarah, Lee, Royce, Phan, K. Luan

“…Social-emotional information processing (SEIP) is critical for appropriate human interaction. It is composed of processes that underlie how we behave towards…”
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Poor inhibitory control is associated with greater stimulation and less sedation following alcohol by Weafer, Jessica, Phan, K. Luan, de Wit, Harriet

“…Rationale and objective Poor inhibitory control is a well-established risk factor for alcohol use disorder (AUD). Similarly, greater sensitivity to the…”
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The interplay of childhood maltreatment and maternal depression in relation to the reward positivity in youth by Suor, Jennifer H, Granros, Maria, Calentino, Alison E, Phan, K Luan, Burkhouse, Katie L

“…Guided by developmental psychopathology and dual-risk frameworks, the present study examined the interplay between childhood maltreatment and maternal major…”
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