Search Results - "Luan, Zuo"
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Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes
Published in Cellular and molecular neurobiology (01-07-2023)“…Human neural stem cells (NSCs) are self-renewing, multipotent cells of the central nervous system (CNS). They are characterized by their ability to…”
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Human Neural Stem Cells with GDNF Site-Specific Integration at AAVS1 by Using AAV Vectors Retained Their Stemness
Published in Neurochemical research (01-04-2018)“…The neural stem cells (NSCs) have the ability to self-renew, and to migrate to pathologically altered regions of the central nervous system. Glial cell derived…”
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Oligogenesis in the "oligovascular unit" involves PI3K/AKT/mTOR signaling in hypoxic-ischemic neonatal mice
Published in Brain research bulletin (01-02-2020)“…•Hypoxia-ischemia induces oligogenesis around vessels in the short term.•The injury of endothelial cells is an early phenomenon that subsequently affects…”
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Identifying the functions of two biomarkers in human oligodendrocyte progenitor cell development
Published in Journal of translational medicine (01-05-2021)“…Human oligodendrocyte precursor cells (hOPCs) are an important source of myelinating cells for cell transplantation to treat demyelinating diseases. Myelin…”
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The Water Transport System in Astrocytes–Aquaporins
Published in Cells (Basel, Switzerland) (01-08-2022)“…Astrocytes have distinctive morphological and functional characteristics, and are found throughout the central nervous system. Astrocytes are now known to be…”
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A novel RIP1/RIP3 dual inhibitor promoted OPC survival and myelination in a rat neonatal white matter injury model with hOPC graft
Published in Stem cell research & therapy (18-08-2021)“…Abstract Background The dual inhibitors of receptor interacting protein kinase-1 and -3 (RIP1 and RIP3) play an important role in cell death processes and…”
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Transplanted Human Oligodendrocyte Progenitor Cells Restore Neurobehavioral Deficits in a Rat Model of Preterm White Matter Injury
Published in Frontiers in neurology (10-11-2021)“…Background: Preterm white matter injury (PWMI) is a common brain injury and a leading cause of life-long neurological deficits in premature infants; however,…”
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Conditioned medium-preconditioned EPCs enhanced the ability in oligovascular repair in cerebral ischemia neonatal rats
Published in Stem cell research & therapy (12-02-2021)“…Oligovascular niche mediates interactions between cerebral endothelial cells and oligodendrocyte precursor cells (OPCs). Disruption of OPC-endothelium trophic…”
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Effects of neural progenitor cell transplantation in children with severe cerebral palsy
Published in Cell transplantation (2012)“…Cerebral palsy (CP) is a chronic nervous system disease that severely damages the physical and developmental health of children. Traditional treatment brings…”
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Valproic acid induces apoptosis in differentiating hippocampal neurons by the release of tumor necrosis factor-α from activated astrocytes
Published in Neuroscience letters (22-06-2011)“…► Valproic acid (VPA) induced neuronal apoptosis in differentiating neruospheres. ► Astrocytes showed morphological changes upon VPA exposure, suggesting…”
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Immunological effects of the intraparenchymal administration of allogeneic and autologous adipose-derived mesenchymal stem cells after the acute phase of middle cerebral artery occlusion in rats
Published in Journal of translational medicine (05-12-2018)“…Adipose-derived mesenchymal stem cell (ADMSC) therapy can promote recovery from cerebral ischemia; however, more information regarding appropriate sources of…”
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TIMP1 in conditioned media of human adipose stromal cells protects neurons against oxygen-glucose deprivation injury
Published in Neuroscience letters (01-01-2015)“…•hASC-CM Protected Neuronal Death Induced by OGD.•hASC-CM Blocked Activation of Caspase-3.•TIMP1 played a role in the neuronal protection of hASC-CM. Adipose…”
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Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppression
Published in iScience (19-05-2023)“…Immune rejection can be reduced using immunosuppressants which are not viable for premature infants. However, desensitization can induce immune tolerance for…”
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Analysis of Adverse Events Related to 720 Cases of Neural Progenitor Cell Transplantation
Published in CNS & neurological disorders drug targets (01-01-2017)“…Cell therapies have shown to be able to improve neurological functions to some extent for patients with refractory central nervous system (CNS) diseases or…”
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Hematopoietic stem cell transplantation for children with β-thalassemia major: multicenter experience in China
Published in World journal of pediatrics : WJP (01-02-2018)“…Background β -Thalassemia major ( β -TM) has become a public health problem in mainland China. Hematopoietic stem cell transplantation (HSCT) has remained the…”
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Neural stem/progenitor cell transplantation for cortical visual impairment in neonatal brain injured patients
Published in Cell transplantation (2013)“…The purpose of this study was to investigate the clinical efficacy of neural stem/progenitor cell (NS/PC) transplantation to treat severe cortical visual…”
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Allogeneic Hematopoietic Stem Cell Transplantation in Thirty-Four Pediatric Cases of Mucopolysaccharidosis—A Ten-Year Report from the China Children Transplant Group
Published in Biology of blood and marrow transplantation (01-11-2016)“…Highlights • We reported multicenter results of allogeneic hematopoietic stem cell transplantation for mucopolysaccharidosis throughout China • This study…”
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Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children
Published in Neural regeneration research (15-11-2012)“…A total of 24 children with cerebral palsy were enrolled in this study and underwent ultrasound guided transplantation of neural stem cells through the lateral…”
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Human neural stem cells transplanted during the sequelae phase alleviate motor deficits in a rat model of cerebral palsy
Published in Cytotherapy (Oxford, England) (01-12-2024)“…•Intracerebral injection of ET-1 modelled key functional and histopathological features of cerebral palsy.•hNSCs transplanted during the sequelae phase…”
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Mesenchymal stromal cells modulate unfolded protein response and preserve β-cell mass in type 1 diabetes
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