Search Results - "Luan, Xiaoyi"
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A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress
Published in International journal of molecular sciences (05-01-2023)“…The mulberry tree ( ) has been cultivated in China for thousands of years. Mulberry Diels-Alder-type adducts (MDAAs) are characteristic constituents of the…”
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Concurrent clinical and pathological response predicts favorable prognosis of patients with gastric cancer after neoadjuvant therapy: a real-world study
Published in BMC cancer (18-10-2023)“…Abstract Background Response of locally advanced gastric cancer (LAGC) to neoadjuvant therapy (NAT) may be associated with prognosis, but which of the clinical…”
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3
The molecular mechanisms of CTHRC1 in gastric cancer by integrating TCGA, GEO and GSA datasets
Published in Frontiers in genetics (19-07-2022)“…Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein…”
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4
Erg6 Acts as a Downstream Effector of the Transcription Factor Flo8 To Regulate Biofilm Formation in Candida albicans
Published in Microbiology spectrum (15-06-2023)“…The yeast-to-hyphal morphotype transition and subsequent biofilm formation are important virulence factors of Candida albicans and are closely associated with…”
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Sex disparity, prediagnosis lifestyle factors, and long-term survival of gastric cancer: a multi-center cohort study from China
Published in BMC cancer (16-09-2024)“…This multi-center cohort study aimed to investigate whether sex and prediagnosis lifestyle affect the prognosis of gastric cancer. Patients with gastric cancer…”
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Trends of older gastric cancer incidence, mortality, and survival in the highest gastric cancer risk area in China: 2010-2019 and prediction to 2024
Published in BMC public health (09-09-2024)“…Gastric cancer is a major health problem worldwide, with a high incidence among older adults. Given the aging overall population, it was crucial to understand…”
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The minimum number of examined lymph nodes was 24 for optimal survival of pathological T2-4 gastric cancer: a multi-center, hospital-based study covering 20 years of data
Published in BMC cancer (21-09-2023)“…Abstract Introduction The current National Comprehensive Cancer Network (NCCN) guidelines recommend that at least 16 lymph nodes should be examined for gastric…”
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Effects of perioperative blood transfusion in gastric cancer patients undergoing gastrectomy: A systematic review and meta-analysis
Published in Frontiers in surgery (17-01-2023)“…The short-term and long-term effects of perioperative blood transfusion (PBT) on patients with gastric cancer are still intriguing. This systematic review and…”
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Application of Survival Quilts for prognosis prediction of gastrectomy patients based on the Surveillance, Epidemiology, and End Results database and China National Cancer Center Gastric Cancer database
Published in Journal of the National Cancer Center (01-06-2024)“…Accurate prognosis prediction is critical for individualized-therapy making of gastric cancer patients. We aimed to develop and test 6-month, 1-, 2-, 3-, 5-,…”
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10
Design, synthesis, and biological evaluation of novel N-Benzyl piperidine derivatives as potent HDAC/AChE inhibitors for Alzheimer’s disease
Published in Bioorganic & medicinal chemistry (15-02-2023)“…[Display omitted] •Thirty-one compounds were designed and synthesized as HDAC/AChE inhibitors for AD.•d5 and d10 exhibited balanced dual enzyme inhibitions…”
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11
Palmarumycin P3 Reverses Mrr1-Mediated Azole Resistance by Blocking the Efflux Pump Mdr1
Published in Antimicrobial agents and chemotherapy (15-03-2022)“…Palmarumycin P3 (PP3) reduces fluconazole-induced transcription to reverse azole resistance in clinical strains. Here, we demonstrated that PP3 restores the…”
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Xylarins A–D, Two Pairs of Diastereoisomeric Isoindoline Alkaloids from the Endolichenic Fungus Xylaria sp
Published in Organic letters (15-10-2021)“…Two pairs of diastereoisomeric isoindoline alkaloids, xylarins A–D (1–4), were isolated from the endolichenic fungus Xylaria sp. Xylarins A and B (1 and 2)…”
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13
Structure-Based Optimization of Novel Sterol 24-C-Methyltransferase Inhibitors for the Treatment of Candida albicans Infections
Published in Journal of medicinal chemistry (13-06-2024)“…Interfering with sterol biosynthesis is an important strategy for developing safe and effective antifungal drugs. We previously identified compound H55 as an…”
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Benzamidine Conjugation Converts Expelled Potential Active Agents into Antifungals against Drug-Resistant Fungi
Published in Journal of medicinal chemistry (12-10-2023)“…Fungal infections present a growing global public health concern, necessitating the development of novel antifungal drugs. However, many potential antifungals,…”
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15
Sex Disparity in Patients with Gastric Cancer: A Systematic Review and Meta-Analysis
Published in Journal of oncology (02-11-2022)“…Objective. This systematic review and meta-analysis aimed to ascertain whether sex-based differences influence clinicopathological characteristics and survival…”
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Bioactive specialised metabolites from the endophytic fungus Xylaria sp. of Cudrania tricuspidata
Published in Phytochemistry (Oxford) (01-04-2022)“…Fourteen undescribed compounds, including five 2,5-diarylcyclopentenones xylariaones A1−B2, seven α-pyrone derivatives xylaripyones A−G, one γ-pyrone…”
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Perioperative Chemotherapy Could Not Improve the Prognosis of Gastric Cancer Patients With Mismatch Repair Deficiency: A Multicenter, Real-World Study
Published in The oncologist (Dayton, Ohio) (01-10-2023)“…Abstract Introduction To date, the role of deficient mismatch repair (dMMR) remains to be proven in gastric cancer, and it is difficult to judge its value in…”
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Blood transfusion might not be recommended for gastric cancer patients with pretransfusion minimum hemoglobin values higher than 90 g/L: a real-world study covering 20 years of 13470 patients
Published in International journal of surgery (London, England) (17-05-2024)“…There was no consistent evidence whether perioperative blood transfusion (PBT) affects the long-term survival of gastric cancer (GC) patients after undergoing…”
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Recent advances of small molecule JNK3 inhibitors for Alzheimer’s disease
Published in Bioorganic chemistry (01-11-2022)“…[Display omitted] •JNK3 has become a promising drug target for Alzheimer’s disease.•Recent progress has been made in treating Alzheimer’s disease with JNK3…”
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The interaction of lead exposure and CCM3 defect plays an important role in regulating angiogenesis through eNOS/NO pathway
Published in Environmental toxicology and pharmacology (01-10-2020)“…•Abnormal retinal vascular angiogenesis in CCM3+/− mice was observed after PbAc exposure comparing with WT mice.•CCM3 gene could be the susceptible gene in…”
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