Search Results - "Luan, Liming"

Targeting Immune Cell Checkpoints during Sepsis by Patil, Naeem K, Guo, Yin, Luan, Liming, Sherwood, Edward R

“…Immunosuppression is increasingly being recognized as one of the causes of increased morbidity and mortality during sepsis. Both innate and adaptive immune…”
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MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists by Lv, Cong, Li, Fengyin, Li, Xiang, Tian, Yuhua, Zhang, Yue, Sheng, Xiaole, Song, Yongli, Meng, Qingyong, Yuan, Shukai, Luan, Liming, Andl, Thomas, Feng, Xu, Jiao, Baowei, Xu, Mingang, Plikus, Maksim V., Dai, Xing, Lengner, Christopher, Cui, Wei, Ren, Fazheng, Shuai, Jianwei, Millar, Sarah E., Yu, Zhengquan

“…MicroRNA-mediated post-transcriptional regulation plays key roles in stem cell self-renewal and tumorigenesis. However, the in vivo functions of specific…”
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MeCP2 inhibits ischemic neuronal injury by enhancing methylation of the FOXO3a promoter to repress the SPRY2-ZEB1 axis by Meng, Lei, Feng, Bin, Luan, Liming, Fang, Zhihao, Zhao, Guangyu

“…Methyl CpG binding protein 2 (MeCP2) is involved in nerve regeneration following ischemic stroke, but the related mechanism remains unclear. Here, we found low…”
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The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism by Fensterheim, Benjamin A, Young, Jamey D, Luan, Liming, Kleinbard, Ruby R, Stothers, Cody L, Patil, Naeem K, McAtee-Pereira, Allison G, Guo, Yin, Trenary, Irina, Hernandez, Antonio, Fults, Jessica B, Williams, David L, Sherwood, Edward R, Bohannon, Julia K

“…Monophosphoryl lipid A (MPLA) is a clinically used TLR4 agonist that has been found to drive nonspecific resistance to infection for up to 2 wk. However, the…”
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The Metabolic Basis of Immune Dysfunction Following Sepsis and Trauma by McBride, Margaret A, Owen, Allison M, Stothers, Cody L, Hernandez, Antonio, Luan, Liming, Burelbach, Katherine R, Patil, Tazeen K, Bohannon, Julia K, Sherwood, Edward R, Patil, Naeem K

“…Critically ill, severely injured and high-risk surgical patients are vulnerable to secondary infections during hospitalization and after hospital discharge…”
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Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection by Hernandez, Antonio, Patil, Naeem K., Stothers, Cody L., Luan, Liming, McBride, Margaret A., Owen, Allison M., Burelbach, Katherine R., Williams, David L., Sherwood, Edward R., Bohannon, Julia K.

“…[Display omitted] Infectious diseases remain a threat to critically ill patients, particularly with the rise of antibiotic-resistant bacteria. Septic shock…”
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IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function by Guo, Yin, Luan, Liming, Patil, Naeem K, Wang, Jingbin, Bohannon, Julia K, Rabacal, Whitney, Fensterheim, Benjamin A, Hernandez, Antonio, Sherwood, Edward R

“…Interleukin 15 is essential for the development and differentiation of NK and memory CD8 (mCD8 ) T cells. Our laboratory previously showed that NK and CD8 T…”
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MyD88-dependent signaling drives toll-like receptor-induced trained immunity in macrophages by Owen, Allison M, Luan, Liming, Burelbach, Katherine R, McBride, Margaret A, Stothers, Cody L, Boykin, Olivia A, Sivanesam, Kalkena, Schaedel, Jessica F, Patil, Tazeen K, Wang, Jingbin, Hernandez, Antonio, Patil, Naeem K, Sherwood, Edward R, Bohannon, Julia K

“…Immunocompromised populations are highly vulnerable to developing life-threatening infections. Strategies to protect patients with weak immune responses are…”
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Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via Acvr2b Suppression by Feng, Bin, Meng, Lei, Luan, Liming, Fang, Zhihao, Zhao, Peng, Zhao, Guangyu

“…Ischemic cerebrovascular disease is a significant and common public health issue worldwide. The emerging roles of mesenchymal stem cells (MSCs)-derived…”
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IL-15 Superagonist Expands mCD8+ T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection by Patil, Naeem K, Luan, Liming, Bohannon, Julia K, Guo, Yin, Hernandez, Antonio, Fensterheim, Benjamin, Sherwood, Edward R

“…Severely burned patients are highly susceptible to opportunistic infections and sepsis, owing to the loss of the protective skin barrier and immunological…”
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Design and Implementation of an Integrated Management System for Backfill Experimental Data by Kou, Yunpeng, Liu, Yuhang, Li, Guoqing, Hou, Jie, Luan, Liming, Wang, Hao

“…With the increase in environmental awareness worldwide, the filling mining method has attracted extensive attention because this method can realize safe and…”
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Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A by Enkhbaatar, Perenlei, Nelson, Christina, Salsbury, John R, Carmical, Joseph R, Torres, Karen E O, Herndon, David, Prough, Donald S, Luan, Liming, Sherwood, Edward R

“…Animal models that mimic human biology are important for successful translation of basic science discoveries into the clinical practice. Recent studies in…”
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Author Correction: MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists by Lv, Cong, Li, Fengyin, Li, Xiang, Tian, Yuhua, Zhang, Yue, Sheng, Xiaole, Song, Yongli, Meng, Qingyong, Yuan, Shukai, Luan, Liming, Andl, Thomas, Feng, Xu, Jiao, Baowei, Xu, Mingang, Plikus, Maksim V., Dai, Xing, Lengner, Christopher, Cui, Wei, Ren, Fazheng, Shuai, Jianwei, Millar, Sarah E., Yu, Zhengquan

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Aldosterone promotes proximal tubular cell apoptosis: role of oxidative stress by Patni, Hitesh, Mathew, Jayant T, Luan, Liming, Franki, Nicholas, Chander, Praveen N, Singhal, Pravin C

“…Aldosterone has attracted significant consideration for its role in the progression of renal injury. Since apoptotic cell loss contributes to the deterioration…”
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Adherens Junction Proteins in the Hamster Uterus: Their Contributions to the Success of Implantation by LIMING LUAN, TIANBING DING, STINNETT, Amanda, REESE, Jeff, PARIA, Bibhash C

“…The adherens junction (AJ) is important for maintaining uterine structural integrity, composition of the luminal environment, and initiation of implantation by…”
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The different HMGA1 expression of total population of glioblastoma cell line U251 and glioma stem cells isolated from U251 by Fan, Haitao, Guo, Hua, Zhang, Ian Y, Liu, Bin, Luan, Liming, Xu, Shangchen, Hou, Xianzeng, Liu, Wei, Zhang, Rui, Wang, Xinsheng, Pang, Qi

“…Abstract The high-mobility group A1 (HMGA1) protein is a non-histone architectural nuclear factor and participates in diverse biological processes, including…”
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Development of a stable, early stage unilateral model of Parkinson's disease in middle-aged rhesus monkeys by Ding, Feng, Luan, Liming, Ai, Yi, Walton, Ashley, Gerhardt, Greg A., Gash, Don M., Grondin, Richard, Zhang, Zhiming

“…An important issue raised in testing new neuroprotective/restorative treatments for Parkinson's disease (PD) is the optimal stage in the disease process to…”
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Pharmacological MRI (phMRI) monitoring of treatment in hemiparkinsonian rhesus monkeys by Luan, Liming, Ding, Feng, Ai, Yi, Andersen, Anders, Hardy, Peter, Forman, Eric, Gerhardt, Greg A, Gash, Don M, Grondin, Richard, Zhang, Zhiming

“…There is a great need for the development of noninvasive, highly sensitive, and widely available imaging methods that can potentially be used to longitudinally…”
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Immunobiology of the IL-15/IL-15Rα complex as an antitumor and antiviral agent by Guo, Yin, Luan, Liming, Patil, Naeem K., Sherwood, Edward R.

“…[Display omitted] •IL-15 potently activates natural killer, NKT and memory CD8+ T cells and is crucial for their normal growth and differentiation.•The…”
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The biology of natural killer cells during sepsis by Guo, Yin, Patil, Naeem K., Luan, Liming, Bohannon, Julia K., Sherwood, Edward R.

“…Summary Natural killer (NK) cells are large granular lymphocytes largely recognized for their importance in tumour surveillance and the host response to viral…”
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