Search Results - "Luan, Jiajie"

Tumor-Associated Macrophages in Hepatocellular Carcinoma: Friend or Foe? by Zhou, Dexi, Luan, Jiajie, Huang, Cheng, Li, Jun

“…Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and it has diverse etiologies with multiple mechanisms. The diagnosis of HCC…”
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TREM2: Potential therapeutic targeting of microglia for Alzheimer's disease by Li, Yueran, Xu, Huifang, Wang, Huifang, Yang, Kui, Luan, Jiajie, Wang, Sheng

“…Alzheimer's disease (AD) is the most common neurodegenerative disease, resulting in the loss of cognitive ability and memory. However, there is no specific…”
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The emerging importance role of m6A modification in liver disease by Wang, Sheng, Gao, Songsen, Ye, Wufei, Li, Yueran, Luan, Jiajie, Lv, Xiongwen

“…N6-methyladenosine (m6A) modification, as one of the most common types of inner RNA modification in eukaryotes, plays a multifunctional role in normal and…”
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Potentiation of the anticancer effect of doxorubicinin drug-resistant gastric cancer cells by tanshinone IIA by Xu, Zhenyu, Chen, Lu, Xiao, Zhangang, Zhu, Yanhong, Jiang, Hui, Jin, Yan, Gu, Cheng, Wu, Yilai, Wang, Lin, Zhang, Wen, Zuo, Jian, Zhou, Dexi, Luan, Jiajie, Shen, Jing

“…Gastric cancer is the fifth commonest cancer and the third cause of cancer-related deaths all over the world. The effectiveness of chemotherapy is still…”
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Cost-effectiveness of sacituzumab govitecan versus single-agent chemotherapy for metastatic triple-negative breast cancer: a trial-based analysis by Wu, Yilai, Hu, Shanshan, Liu, Xiaolin, Chen, Yang, Luan, Jiajie, Wang, Shuowen

“…Sacituzumab govitecan (SG) has recently been approved in China for the post-line treatment of metastatic triple-negative breast cancer (mTNBC). SG…”
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Emerging Importance of Chemokine Receptor CXCR4 and Its Ligand in Liver Disease by Wang, Sheng, Gao, Songsen, Li, Yueran, Qian, Xueyi, Luan, Jiajie, Lv, Xiongwen

“…Chemokine receptors are members of the G protein-coupled receptor superfamily, which together with chemokine ligands form chemokine networks to regulate…”
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Problems and challenges encountered by Chinese medical institutions in implementing the national centralized drug procurement by Zhang, Wen, Xu, Qingwen, Peng, Jing, Zhang, Xiaotong, Chen, Lu, Wu, Yilai, Yang, Kui, Luan, Jiajie, Liu, Xiaoyun

“…Objective: The problems and challenges encountered by Chinese medical institutions in implementing the national centralized drug procurement was investigated…”
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Promising landscape for regulating macrophage polarization: epigenetic viewpoint by Zhou, Dexi, Yang, Kui, Chen, Lu, Zhang, Wen, Xu, Zhenyu, Zuo, Jian, Jiang, Hui, Luan, Jiajie

“…Macrophages are critical myeloid cells with the hallmark of phenotypic heterogeneity and functional plasticity. Macrophages phenotypes are commonly described…”
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Comprehensive genomic signature of pyroptosis-related genes and relevant characterization in hepatocellular carcinoma by Wang, Sheng, Gao, Songsen, Shan, Liang, Qian, Xueyi, Luan, Jiajie, Lv, Xiongwen

“…Currently, the most predominant type of liver cancer is hepatocellular carcinoma (HCC), which is also the fourth leading cause of cancer-related death in the…”
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Harnessing noncoding RNA‐based macrophage polarization: Emerging therapeutic opportunities for fibrosis by Zhou, Dexi, Wu, Yilai, Wang, Sheng, Li, Jun, Luan, Jiajie

“…Aim Organ fibrosis is a common pathological outcome of persistent tissue injury correlated with organ failure and death. Although current antifibrotic…”
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Combination of Valsartan and Melatonin to Treat Non-Dipping Hypertension Rats via Circadian Clock System by Kui, Yang, Yanyun, Ding, Wan, Jin, Yaqin, Wang, Lu, Chen, Wen, Zhang, Wusan, Wang, Zhangqing, Ma, Jiajie, Luan

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Renal Protection of In Vivo Administration of Tempol in Streptozotocin-Induced Diabetic Rats by Luan, Jiajie, Li, Weiping, Han, Jia, Zhang, Wen, Gong, Huiling, Ma, Rong

“…The present study was carried out to investigate the protective effects of tempol on renal function and the underlying mechanism in streptozotocin-induced…”
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ARMc8: a potential diagnostic and therapeutic target for cancers by Zhou, Dexi, PhD, Zhang, Wen, MS, Wang, Yaqin, MS, Chen, Lu, MS, Luan, Jiajie, PhD

“…[...]ARMc8 might act as an independent prognostic factor for non-small cell lung cancer, which promotes the proliferation and invasion of cancer cells through…”
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Effect of CYP3A5 Gene Polymorphisms on Tacrolimus Blood Concentrations and Adverse Events in Allogeneic Hematopoietic Stem Cell Transplant Patients by Jiang, Jia, Luan, Jiajie

“…Tacrolimus is the core basic immunosuppressant after transplantation. Cytochrome P450 3A5 (CYP3A5) is the main enzyme involved in tacrolimus metabolism, and…”
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Inhibition of Endoplasmic Reticulum Stress Attenuated Ethanol-Induced Exosomal miR-122 and Acute Liver Injury in Mice by Wang, Sheng, Luan, Jiajie, Lv, Xiongwen

“…In acute alcoholic liver injury, alcohol can directly or indirectly induce endoplasmic reticulum stress (ERS) to participate in liver injury, and it is found…”
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Cost–utility analysis of trastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer in Chinese setting by Hu, Shanshan, Wu, Yilai, Luan, Jiajie, Wang, Shuowen, Fan, Guorong

“…Purpose Trastuzumab deruxtecan (T-DXd) expressed substantial improvement in the progression-free survival and overall survival contrasted with trastuzumab…”
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The role of the CD39–CD73–adenosine pathway in liver disease by Wang, Sheng, Gao, Songsen, Zhou, Dexi, Qian, Xueyi, Luan, Jiajie, Lv, Xiongwen

“…Extracellular adenosine triphosphate (ATP) is a danger signal released by dying and damaged cells, and it functions as an immunostimulatory signal that…”
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Chlorogenic acid alleviate kidney fibrosis through regulating TLR4/NF-қB mediated oxidative stress and inflammation by Jiao, Hao, Zhang, Meijuan, Xu, Wuqin, Pan, Tongshuai, Luan, Jiajie, Zhao, Yingjie, Zhang, Zhirui

“…Chlorogenic acid (CGA), a phenolic acid produced by the interaction of Caffeic acid and Quinic acid, is considered to be the main active ingredient in many…”
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Emerging role of m6A modification in fibrotic diseases and its potential therapeutic effect by Ye, Wufei, Lv, Xiongwen, Gao, Songsen, Li, Yueran, Luan, Jiajie, Wang, Sheng

“…[Display omitted] Fibrosis can occur in a variety of organs such as the heart, lung, liver and kidney, and its pathological changes are mainly manifested by an…”
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A Multifunctional Liposome for Synergistic Chemotherapy with Ferroptosis Activation of Triple-Negative Breast Cancer by Chai, Jingjing, Hu, Jiawei, Wang, Tao, Bao, Xing, Luan, Jiajie, Wang, Yan

“…There is an urgent need to develop efficient treatments for highly invasive triple-negative breast cancer (TNBC) with a high rate of postoperative. Baicalin…”
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