Search Results - "Lu, Yaoyao"
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Contraction reserve in high resolution manometry is correlated with lower esophageal acid exposure time in patients with normal esophageal motility: A retrospective observational study
Published in PloS one (02-11-2023)“…Background In high resolution manometry (HRM), distal contractile integral post multiple rapid swallow augmentation is considered as contraction reserve. The…”
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Prevalence, Risk Factors, and Genotypes of Toxoplasma gondii in Food Animals and Humans (2000-2017) From China
Published in Frontiers in microbiology (11-09-2018)“…as a food-borne pathogen, the infection of it in food animals has relation with human toxoplasmosis, but the trends and epidemiological features of infections…”
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3
Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model
Published in Neurochemical research (01-04-2020)“…Brain injury has been proposed as the major cause of the poor outcomes associated with intracerebral hemorrhage (ICH). Emerging evidence indicates that the…”
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4
CRISPR-Cas9 delivery strategies with engineered extracellular vesicles
Published in Molecular therapy. Nucleic acids (12-12-2023)“…Therapeutic genome editing has the potential to cure diseases by directly correcting genetic mutations in tissues and cells. Recent progress in the CRISPR-Cas9…”
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Prevalence of suicide attempts and correlates among first-episode and untreated major depressive disorder patients with comorbid dyslipidemia of different ages of onset in a Chinese Han population: a large cross-sectional study
Published in BMC psychiatry (04-01-2023)“…Patients with dyslipidemia are at increased risk for suicide, especially those with major depressive disorder (MDD). Few studies have investigated the…”
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Antidepressants in the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis
Published in PloS one (16-06-2016)“…Antidepressants have been empirically used in the treatment of functional dyspepsia (FD). However, results from recent clinical trials investigating their…”
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CRISPR/Cas9-mediated knockout of APOC3 stabilizes plasma lipids and inhibits atherosclerosis in rabbits
Published in Lipids in health and disease (18-12-2021)“…High levels of apolipoprotein C3 (APOC3) can lead to hypertriglyceridemia, which increases the risk of cardiovascular disease. We aim to create APOC3-knockout…”
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Insecticidal Activity of Artemisia vulgaris Essential Oil and Transcriptome Analysis of Tribolium castaneum in Response to Oil Exposure
Published in Frontiers in genetics (25-06-2020)“…Red flour beetle ( Tribolium castaneum ) is one of the most destructive pests of stored cereals worldwide. The essential oil (EO) of Artemisia vulgaris…”
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Prime editing optimized RTT permits the correction of the c.8713C>T mutation in DMD gene
Published in Molecular therapy. Nucleic acids (13-12-2022)“…Duchenne muscular dystrophy is a severe debilitating genetic disease caused by different mutations in the DMD gene leading to the absence of dystrophin protein…”
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A novel liver zonation phenotype-associated molecular classification of hepatocellular carcinoma
Published in Frontiers in immunology (02-03-2023)“…Liver zonation is a unique phenomenon in which the liver exhibits distinct functions among hepatocytes along the radial axis of the lobule. This phenomenon can…”
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Emerging Perspectives on Prime Editor Delivery to the Brain
Published in Pharmaceuticals (Basel, Switzerland) (11-06-2024)“…Prime editing shows potential as a precision genome editing technology, as well as the potential to advance the development of next-generation nanomedicine for…”
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12
A review of deep learning methods for ligand based drug virtual screening
Published in Fundamental research (Beijing) (01-07-2024)“…Drug discovery is costly and time consuming, and modern drug discovery endeavors are progressively reliant on computational methodologies, aiming to mitigate…”
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13
Relationship between anemia and its correlates and cognitive function in Chinese patients with chronic schizophrenia: A large cross-sectional study
Published in Schizophrenia research. Cognition (01-06-2024)“…Although both anemia and schizophrenia (SCZ) can cause cognitive decline, it is unclear whether anemia worsens cognitive decline in patients with SCZ. The…”
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Integrated omics analysis reveals the epigenetic mechanism of visceral hypersensitivity in IBS-D
Published in Frontiers in pharmacology (16-03-2023)“…IBS-D is a common functional bowel disease with complex etiology and without biomarker. The pathological and physiological basis of IBS-D focuses on visceral…”
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Palladium-Catalyzed C2-Selective Direct Arylation of Benzo[b]thiophene 1,1-Dioxides with Arylboronic Acids
Published in ACS omega (09-01-2024)“…A novel oxidative cross-coupling of benzo[b]thiophene 1,1-dioxides with arylboronic acids was reported. The efficient reaction occurred at the C2-position…”
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Generation of hyperlipidemic rabbit models using multiple sgRNAs targeted CRISPR/Cas9 gene editing system
Published in Lipids in health and disease (18-03-2019)“…To generate novel rabbit models with a large-fragment deletion of either LDL receptor (LDLR) and/or apolipoprotein (apoE) genes for the study of hyperlipidemic…”
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Several circulating miRNAs related to hyperlipidemia and atherosclerotic cardiovascular diseases
Published in Lipids in health and disease (22-04-2019)“…In recent years, an increasing number of studies have proved that circulating miRNAs could be used for the early diagnosis of cardiovascular diseases and even…”
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DNA-binding protein prediction based on deep transfer learning
Published in Mathematical biosciences and engineering : MBE (01-01-2022)“…The study of DNA binding proteins (DBPs) is of great importance in the biomedical field and plays a key role in this field. At present, many researchers are…”
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Toxoplasma gondii and Neospora caninum in farm-reared ostriches (Struthio camelus) in China
Published in BMC veterinary research (11-10-2017)“…The parasites Toxoplasma gondii (T. gondii) and Neospora caninum (N. caninum) are globally distributed; they infect warm-blooded animals, including many avian…”
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Study on the mechanism of Danshen-Guizhi drug pair in the treatment of ovarian cancer based on network pharmacology and in vitro experiment
Published in PeerJ (San Francisco, CA) (06-04-2022)“…Our study aims to explore the active components and mechanisms of the Danshen-Guizhi drug pair in treating ovarian cancer by network pharmacology and…”
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