Search Results - "Lu, Xiang‐Ran"

PD-L1 negatively regulates antifungal immunity by inhibiting neutrophil release from bone marrow by Yu, Yao, Wang, Rong-Rong, Miao, Nai-Jun, Tang, Jia-Jie, Zhang, Yun-Wei, Lu, Xiang-Ran, Yan, Pei-Yi, Wang, Jing, Jia, Xin-Ming

“…Programmed death ligand 1 (PD-L1) has been shown to be inducibly expressed on neutrophils to suppress host immunity during polymicrobial sepsis, virus and…”
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Functional characterization of 27 CYP3A4 variants on macitentan metabolism in vitro by Li, Ying‐hui, Lu, Xiang‐ran, Lin, Qian‐meng, Huang, Huan‐le, Liang, Xiao‐long, Cai, Jian‐ping, Cui, Ju, Hu, Guo‐xin

“…Objective Macitentan is a new choice for pulmonary hypertension treatment which is converted to active metabolite ACT132577 by human cytochrome P450 3A4. Human…”
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Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro by liu, Qian, Ou‐Yang, Qiu‐Geng, Lin, Qian‐Meng, Lu, Xiang‐Ran, Ma, Ya‐Qing, Li, Ying‐Hui, Xu, Ren‐Ai, Lin, Dong‐dong, Hu, Guo‐Xin, Cai, Jian‐Ping

“…Saxagliptin is a dipeptidyl peptidase 4 (DPP‐4) inhibitor widely used in patients with type 2 diabetes. It can increase the amount of insulin after meals and…”
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Characterization of Genetic Variation in CYP3A4 on the Metabolism of Cabozantinib in Vitro by Lin, Qian-meng, Li, Ying-hui, Lu, Xiang-ran, Wang, Ru, Pang, Ni-hong, Xu, Ren-ai, Cai, Jian-ping, Hu, Guo-xin

“…Cabozantinib is a multityrosine kinase inhibitor and has a wide range of applications in the clinic, whose metabolism is predominately dependent on CYP3A4…”
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Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro by Zhou, Xiao-Yang, Hu, Xiao-Xia, Wang, Chen-Chen, Lu, Xiang-Ran, Chen, Zhe, Liu, Qian, Hu, Guo-Xin, Cai, Jian-Ping

“…Cytochrome P450 3A4 (CYP3A4) enzyme activity is known to show considerable ethnic heterogeneity and inter-individual differences, affecting the outcome of drug…”
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Identification and Enzymatic Activity Evaluation of a Novel CYP2C9 Allelic Variant Discovered in a Patient by Zhou, Xiao-Yang, Lu, Xiang-Ran, Li, Ying-Hui, Ma, Ya-Qing, Zhao, Shi-Wen, Wang, Fang, Xu, Ren-Ai, Hu, Guo-Xin, Cai, Jian-Ping

“…Warfarin is a widely prescribed anticoagulant but the doses required to attain the optimum therapeutic effect exhibit dramatic inter-individual variability…”
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Determination and pharmacokinetic study of Enasidenib in rat plasma by UPLC–MS/MS by Pang, Ni-hong, Liu, Qian, Lu, Xiang-ran, Yang, Su-fen, Lin, Dong-dong, Hu, Guo-xin

“…•There were no published reports of methods for detecting Enasidenib. In a word, this was the first paper to describe measurement of Enasidenib in rat…”
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Amorphization of Ni_（61）Nb_（39） Alloy by Laser Surface Treatment by Zhong-xiang LU Ran LI Yan LI Tao ZHANG

“…The surface of Ni_（61）Nb_（39） crystalline ingot was treated by laser surface melting with different processing parameters.A fully amorphous layer with a…”
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