Search Results - "Lu, Weisi"

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation by Dumas, Sébastien J, Meta, Elda, Borri, Mila, Goveia, Jermaine, Rohlenova, Katerina, Conchinha, Nadine V, Falkenberg, Kim, Teuwen, Laure-Anne, de Rooij, Laura, Kalucka, Joanna, Chen, Rongyuan, Khan, Shawez, Taverna, Federico, Lu, Weisi, Parys, Magdalena, De Legher, Carla, Vinckier, Stefan, Karakach, Tobias K, Schoonjans, Luc, Lin, Lin, Bolund, Lars, Dewerchin, Mieke, Eelen, Guy, Rabelink, Ton J, Li, Xuri, Luo, Yonglun, Carmeliet, Peter

“…Renal endothelial cells from glomerular, cortical, and medullary kidney compartments are exposed to different microenvironmental conditions and support…”
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The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation by He, Quanyuan, Kim, Hyeung, Huang, Rui, Lu, Weisi, Tang, Mengfan, Shi, Fengtao, Yang, Dong, Zhang, Xiya, Huang, Junjiu, Liu, Dan, Songyang, Zhou

“…In mammals, DNA methylation is essential for protecting repetitive sequences from aberrant transcription and recombination. In some developmental contexts…”
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ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer by Li, Kai, Wu, Jian-lin, Qin, Baifu, Fan, Zongmin, Tang, Qin, Lu, Weisi, Zhang, Haipeng, Xing, Fan, Meng, Manqi, Zou, Shaomin, Wei, Wenxia, Chen, Honglei, Cai, Jian, Wang, Huaiming, Zhang, Hui, Cai, Jiayue, Fang, Ling, Bian, Xiqing, Chen, Chuangqi, Lan, Ping, Ghesquière, Bart, Fang, Lekun, Lee, Mong-Hong

“…The Serine–Glycine–One-Carbon (SGOC) pathway is pivotal in multiple anabolic processes. Expression levels of SGOC genes are deregulated under tumorigenic…”
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Vascular stem/progenitor cells: functions and signaling pathways by Lu, Weisi, Li, Xuri

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Expression and function of PDGF-C in development and stem cells by Tian, Yi, Zhan, Ying, Jiang, Qin, Lu, Weisi, Li, Xuri

“…Platelet-derived growth factor C (PDGF-C) is a relatively new member of the PDGF family, discovered nearly 20 years after the finding of platelet-derived…”
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Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy by Lu, Weisi, Xie, Yunling, Huang, Binjie, Ma, Tenghui, Wang, Huaiming, Deng, Boxiong, Zou, Shaomin, Wang, Wencong, Tang, Qin, Yang, Ziqing, Li, Xuri, Wang, Lei, Fang, Lekun

“…Radiation proctopathy (RP) is characterized by inflammation of colorectal tissue and is a common complication of radiation therapy for pelvic malignancies with…”
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ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development by Fang, Lekun, Lu, Weisi, Choi, Hyun Ho, Yeung, Sai-Ching J., Tung, Jung-Yu, Hsiao, Chwan-Deng, Fuentes-Mattei, Enrique, Menter, David, Chen, Chuangqi, Wang, Lei, Wang, Jianping, Lee, Mong-Hong

“…Biomarkers for predicting prognosis are critical to treating colorectal cancer (CRC) patients. We found that CSN6, a subunit of COP9 signalosome, is…”
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The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency by Lu, Weisi, Yu, Jianping, Shi, Fengtao, Zhang, Jianing, Huang, Rui, Yin, Shanshan, Songyang, Zhou, Huang, Junjiu

“…Small nucleolar RNA host gene 3 (Snhg3) is a long non-coding RNA (lncRNA) that was shown to participate in the tumorigenesis of certain cancers. However,…”
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The Death-inducer Obliterator 1 (Dido1) Gene Regulates Embryonic Stem Cell Self-renewal by Liu, Yinyin, Kim, Hyeung, Liang, Jiancong, Lu, Weisi, Ouyang, Bin, Liu, Dan, Songyang, Zhou

“…The regulatory network of factors that center on master transcription factors such as Oct4, Nanog, and Sox2 help maintain embryonic stem (ES) cells and ensure…”
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Rho GDP‐dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer by Huang, Dandan, Lu, Weisi, Zou, Shaomin, Wang, Huaiming, Jiang, Yuanling, Zhang, Xiya, Li, Pengqing, Songyang, Zhou, Wang, Lei, Wang, Jianping, Huang, Junjiu, Fang, Lekun

“…Rho GDP‐dissociation inhibitor α (RhoGDIα) is an essential regulator for Rho GTPases. Although RhoGDIα may serve as an oncogene in colorectal cancer (CRC), the…”
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VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway by Lee, Chunsik, Chen, Rongyuan, Sun, Guangli, Liu, Xialin, Lin, Xianchai, He, Chang, Xing, Liying, Liu, Lixian, Jensen, Lasse D., Kumar, Anil, Langer, Harald F., Ren, Xiangrong, Zhang, Jianing, Huang, Lijuan, Yin, Xiangke, Kim, JongKyong, Zhu, Juanhua, Huang, Guanqun, Li, Jiani, Lu, Weiwei, Chen, Wei, Liu, Juanxi, Hu, Jiaxin, Sun, Qihang, Lu, Weisi, Fang, Lekun, Wang, Shasha, Kuang, Haiqing, Zhang, Yihan, Tian, Geng, Mi, Jia, Kang, Bi-Ang, Narazaki, Masashi, Prodeus, Aaron, Schoonjans, Luc, Ornitz, David M., Gariepy, Jean, Eelen, Guy, Dewerchin, Mieke, Yang, Yunlong, Ou, Jing-Song, Mora, Antonio, Yao, Jin, Zhao, Chen, Liu, Yizhi, Carmeliet, Peter, Cao, Yihai, Li, Xuri

“…Although VEGF-B was discovered as a VEGF-A homolog a long time ago, the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings…”
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Vascular stem/progenitor cells: functions and signaling pathways by Lu, Weisi, Li, Xuri

“…Vascular stem/progenitor cells (VSCs) are an important source of all types of vascular cells needed to build, maintain, repair, and remodel blood vessels…”
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PDGFs and their receptors in vascular stem/progenitor cells: Functions and therapeutic potential in retinal vasculopathy by Lu, Weisi, Li, Xuri

“…Vascular stem/progenitor cells (VSCs) include endothelial progenitor cells, smooth muscle progenitor cells, pericytes, and mesenchymal stem cells. VSCs can…”
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Telomeres—structure, function, and regulation by Lu, Weisi, Zhang, Yi, Liu, Dan, Songyang, Zhou, Wan, Ma

“…In mammals, maintenance of the linear chromosome ends (or telomeres) involves faithful replication of genetic materials and protection against DNA damage…”
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Ten-Eleven Translocation 1 (Tet1) Is Regulated by O-Linked N-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells by Shi, Feng-Tao, Kim, Hyeung, Lu, Weisi, He, Quanyuan, Liu, Dan, Goodell, Margaret A., Wan, Ma, Songyang, Zhou

“…As a member of the Tet (Ten-eleven translocation) family proteins that can convert 5-methylcytosine (5mC) to 5-hydroxylmethylcytosine (5hmC), Tet1 has been…”
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The Trithorax Group Protein Ash2l Is Essential for Pluripotency and Maintaining Open Chromatin in Embryonic Stem Cells by Wan, Ma, Liang, Jiancong, Xiong, Yuanyan, Shi, Fengtao, Zhang, Yi, Lu, Weisi, He, Quanyuan, Yang, Dong, Chen, Rui, Liu, Dan, Barton, Michelle, Songyang, Zhou

“…Embryonic stem (ES) cells exhibit general characteristics of open chromatin, a state that may be necessary for ES cells to efficiently self-renew while…”
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The retinal pigment epithelium: Functions and roles in ocular diseases by Wang, Shasha, Li, Wanhong, Chen, Min, Cao, Yihai, Lu, Weisi, Li, Xuri

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VEGF-B is a potent antioxidant by Arjunan, Pachiappan, Lin, Xianchai, Tang, Zhongshu, Du, Yuxiang, Kumar, Anil, Liu, Lixian, Yin, Xiangke, Huang, Lijuan, Chen, Wei, Chen, Qishan, Ye, Zhimin, Wang, Shasha, Kuang, Haiqing, Zhou, Linbin, Xu, Kai, Chen, Xue, Zeng, Haitao, Lu, Weisi, Cao, Yihai, Liu, Yizhi, Zhao, Chen, Li, Xuri

“…VEGF-B was discovered a long time ago. However, unlike VEGF-A, whose function has been extensively studied, the function of VEGF-B and the mechanisms involved…”
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Novel multi-targeted inhibitors suppress ocular neovascularization by regulating unique gene sets by Yin, Xiangke, Lin, Xianchai, Ren, Xiangrong, Yu, Bo, Liu, Lixian, Ye, Zhimin, Chen, Qishan, Lee, Chunsik, Lu, Weisi, Yu, Dechao, Li, Xuri

“…[Display omitted] Neovascular diseases, such as many cancers and ocular disorders, are life threatening and devastating. Although anti-vascular endothelial…”
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Interaction Between Sympk and Oct4 Promotes Mouse Embryonic Stem Cell Proliferation by Yu, Jianping, Lu, Weisi, Ge, Tianyu, Huang, Rui, Chen, Bohong, Ye, Miaoman, Bai, Yaofu, Shi, Guang, Songyang, Zhou, Ma, Wenbin, Huang, Junjiu

“…The scaffold protein Symplekin (Sympk) is involved in cytoplasmic RNA polyadenylation, transcriptional modulation, and the regulation of epithelial…”
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