Search Results - "Lu, Wei Ping"

Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants by Smith, Bryan D., Kaufman, Michael D., Lu, Wei-Ping, Gupta, Anu, Leary, Cynthia B., Wise, Scott C., Rutkoski, Thomas J., Ahn, Yu Mi, Al-Ani, Gada, Bulfer, Stacie L., Caldwell, Timothy M., Chun, Lawrence, Ensinger, Carol L., Hood, Molly M., McKinley, Arin, Patt, William C., Ruiz-Soto, Rodrigo, Su, Ying, Telikepalli, Hanumaiah, Town, Ajia, Turner, Benjamin A., Vogeti, Lakshminarayana, Vogeti, Subha, Yates, Karen, Janku, Filip, Abdul Razak, Albiruni Ryan, Rosen, Oliver, Heinrich, Michael C., Flynn, Daniel L.

“…Ripretinib (DCC-2618) was designed to inhibit the full spectrum of mutant KIT and PDGFRA kinases found in cancers and myeloproliferative neoplasms,…”
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Differences of yield and nitrogen use efficiency under different applications of slow release fertilizer in spring maize by LI, Guang-hao, CHENG, Gui-gen, LU, Wei-ping, LU, Da-lei

“…Excessive or insufficient application of fertilizer has raised broader concerns regarding soil and environmental degradation. One-time application of slow…”
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Discovery of acyl ureas as highly selective small molecule CSF1R kinase inhibitors by Caldwell, Timothy M., Kaufman, Michael D., Wise, Scott C., Mi Ahn, Yu, Hood, Molly M., Lu, Wei-Ping, Patt, William C., Samarakoon, Thiwanka, Vogeti, Lakshminarayana, Vogeti, Subha, Yates, Karen M., Bulfer, Stacie L., Le Bourdonnec, Bertrand, Smith, Bryan D., Flynn, Daniel L.

“…[Display omitted] Based on the structure of an early lead identified in Deciphera’s proprietary compound collection of switch control kinase inhibitors and…”
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Effects of multimicronutrient supplementation during pregnancy on postnatal growth of children under 5 years of age: a meta-analysis of randomized controlled trials by Lu, Wei-Ping, Lu, Min-Shan, Li, Zong-Hua, Zhang, Cai-Xia

“…The beneficial effect of antenatal multiple micronutrients supplementation on infant birth outcomes has been proposed by previous meta-analyses. However, their…”
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N, P and K use efficiency and maize yield responses to fertilization modes and densities by LI, Guang-hao, CHENG, Qian, LI, Long, LU, Da-lei, LU, Wei-ping

“…Optimal planting density and proper fertilization method are important factors to improve maize yield and nutrient utilization. A two-year (2016 and 2017)…”
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Effects of post-silking water deficit on the leaf photosynthesis and senescence of waxy maize by YE, Yu-xiu, WEN, Zhang-rong, YANG, Huan, LU, Wei-ping, LU, Da-lei

“…Waxy maize is widely cultivated under rainfed conditions and frequently suffers water shortage during the late growth stage. In this study, a pot trial was…”
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Preliminary Evaluation of Rapid Visual Identification of Burkholderia pseudomallei Using a Newly Developed Lateral Flow Strip-Based Recombinase Polymerase Amplification (LF-RPA) System by Li, Jin, Zhong, Qiu, Shang, Mei-Yun, Li, Min, Jiang, Yuan-Su, Zou, Jia-Jun, Ma, Shan-Shan, Huang, Qing, Lu, Wei-Ping

“…is an important infectious disease pathogen that can cause melioidosis. Melioidosis is mainly prevalent in Thailand, northern Australia and southern China and…”
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Weakened carbon and nitrogen metabolisms under post-silking heat stress reduce the yield and dry matter accumulation in waxy maize by YANG, Huan, GU, Xiao-tian, DING, Meng-qiu, LU, Wei-ping, LU, Da-lei

“…Post-silking high temperature is one of the abiotic factors that affects waxy maize (Zea mays L. sinensis Kulesh) growth in southern China. We conducted a pot…”
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Development of a novel integrated isothermal amplification system for detection of bacteria-spiked blood samples by Li, Jin, Shang, Mei-Yun, Deng, Shao-Li, Li, Min, Su, Ning, Ren, Xiao-Dong, Sun, Xian-Ge, Li, Wen-Man, Li, Yu-Wei, Li, Ruo-Xu, Huang, Qing, Lu, Wei-Ping

“…Bloodstream infection (BSI) caused by bacteria is highly pathogenic and lethal, and easily develops whole-body inflammatory state. Immediate identification of…”
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Ski, a modulator of wound healing and scar formation in the rat skin and rabbit ear by Li, Ping, Liu, Ping, Xiong, Ren-Ping, Chen, Xing-Yun, Zhao, Yan, Lu, Wei-Ping, Liu, Xia, Ning, Ya-Lei, Yang, Nan, Zhou, Yuan-Guo

“…We recently demonstrated that Ski is a novel wound healing-related factor that promotes fibroblast proliferation and inhibits collagen secretion. Here, we show…”
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Effects of high temperature during grain filling on physicochemical properties of waxy maize starch by LU, Da-lei, YANG, Huan, SHEN, Xin, LU, Wei-ping

“…Understanding the waxy maize starch physicochemical properties response to heat stress during grain filling could improve starch quality.The effects of heat…”
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Enhanced Separation Efficiency and Purity of Circulating Tumor Cells Based on the Combined Effects of Double Sheath Fluids and Inertial Focusing by Li, Bo-Wen, Wei, Kun, Liu, Qi-Qi, Sun, Xian-Ge, Su, Ning, Li, Wen-Man, Shang, Mei-Yun, Li, Jin-Mi, Liao, Dan, Li, Jin, Lu, Wei-Ping, Deng, Shao-Li, Huang, Qing

“…Circulating tumor cells (CTCs) play a crucial role in solid tumor metastasis, but obtaining high purity and viability CTCs is a challenging task due to their…”
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The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors by Harney, Allison S., Karagiannis, George S., Pignatelli, Jeanine, Smith, Bryan D., Kadioglu, Ece, Wise, Scott C., Hood, Molly M., Kaufman, Michael D., Leary, Cynthia B., Lu, Wei-Ping, Al-Ani, Gada, Chen, Xiaoming, Entenberg, David, Oktay, Maja H., Wang, Yarong, Chun, Lawrence, De Palma, Michele, Jones, Joan G., Flynn, Daniel L., Condeelis, John S.

“…Abstract Tumor-infiltrating myeloid cells promote tumor progression by mediating angiogenesis, tumor cell intravasation, and metastasis, which can offset the…”
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The infection of Mycoplasma hominis after total knee replacement: Case report and literature review by Qiu, Hong-Jiu, Lu, Wei-Ping, Li, Min, Wang, Zi-Ming, Du, Quan-Yin, Wang, Ai-Min, Xiong, Yan

“…The Mycoplasma hominis infection is a rare postoperative complication after joint replacement. Based on our knowledge, there were only two cases reported by…”
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Effect of Shading During Grain Filling on the Physicochemical Properties of Fresh Waxy Maize by LU, Da-lei, SUN, Xu-li, WANG, Xin, YAN, Fa-bao, LU, Wei-ping

“…Grain physicochemical properties determine the table quality of fresh waxy maize. Two waxy maize varieties, Suyunuo 5 （shading tolerant） and FHN003 （shading…”
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Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers by Peng, Sheng-Bin, Henry, James R., Kaufman, Michael D., Lu, Wei-Ping, Smith, Bryan D., Vogeti, Subha, Rutkoski, Thomas J., Wise, Scott, Chun, Lawrence, Zhang, Youyan, Van Horn, Robert D., Yin, Tinggui, Zhang, Xiaoyi, Yadav, Vipin, Chen, Shih-Hsun, Gong, Xueqian, Ma, Xiwen, Webster, Yue, Buchanan, Sean, Mochalkin, Igor, Huber, Lysiane, Kays, Lisa, Donoho, Gregory P., Walgren, Jennie, McCann, Denis, Patel, Phenil, Conti, Ilaria, Plowman, Gregory D., Starling, James J., Flynn, Daniel L.

“…LY3009120 is a pan-RAF and RAF dimer inhibitor that inhibits all RAF isoforms and occupies both protomers in RAF dimers. Biochemical and cellular analyses…”
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Genomic features and virulence characteristics of a rare Burkholderia thailandensis strain causing human infection by Li, Jin, Zhong, Qiu, Li, Jian, Chong, Hui-Min, Wang, Li-Xin, Xing, Yun, Lu, Wei-Ping

“…is a clinically rare opportunistic pathogen in the genus , and the genomic features and virulence characteristics of strains that cause human infection remain…”
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Vimseltinib: A Precision CSF1R Therapy for Tenosynovial Giant Cell Tumors and Diseases Promoted by Macrophages by Smith, Bryan D, Kaufman, Michael D, Wise, Scott C, Ahn, Yu Mi, Caldwell, Timothy M, Leary, Cynthia B, Lu, Wei-Ping, Tan, Gege, Vogeti, Lakshminarayana, Vogeti, Subha, Wilky, Breelyn A, Davis, Lara E, Sharma, Maitreyi, Ruiz-Soto, Rodrigo, Flynn, Daniel L

“…Macrophages can be co-opted to contribute to neoplastic, neurologic, and inflammatory diseases. Colony-stimulating factor 1 receptor (CSF1R)-dependent…”
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Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment of Tenosynovial Giant Cell Tumor (TGCT) by Caldwell, Timothy M., Ahn, Yu Mi, Bulfer, Stacie L., Leary, Cynthia B., Hood, Molly M., Lu, Wei-Ping, Vogeti, Lakshminarayana, Vogeti, Subha, Kaufman, Michael D., Wise, Scott C., Le Bourdonnec, Bertrand, Smith, Bryan D., Flynn, Daniel L.

“…[Display omitted] Based on knowledge of kinase switch-control inhibition and using a combination of structure-based drug design and standard medicinal…”
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Oxidative metabolism of inorganic sulfur compounds by bacteria by Kelly, D P, Shergill, J K, Lu, W P, Wood, A P

“…The history of the elucidation of the microbiology and biochemistry of the oxidation of inorganic sulfur compounds in chemolithotrophic bacteria is briefly…”
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