Search Results - "Lu, Sophie D"
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FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Published in Cancer research (Chicago, Ill.) (02-09-2022)“…Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we…”
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DIPG-19. FOXR2 is an oncogenic driver across pediatric and adult cancers
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology…”
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Abstract 3562: Dissecting mechanisms underlying FOXR2 -mediated gliomagenesis in diffuse midline gliomas
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Background: Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating…”
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Abstract 5730: FOXR2 is an oncogenic driver across adult and pediatric cancers
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology…”
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Journal Article