Search Results - "Lu, Robin A"

Onvansertib treatment overcomes olaparib resistance in high-grade ovarian carcinomas by Chiappa, Michela, Decio, Alessandra, Guarrera, Luca, Mengoli, Ilaria, Karki, Anju, Yemane, Divora, Ghilardi, Carmen, Scanziani, Eugenio, Canesi, Simone, Barbera, Maria C., Craparotta, Ilaria, Bolis, Marco, Fruscio, Robert, Grasselli, Chiara, Ceruti, Tommaso, Zucchetti, Massimo, Patterson, Jesse C., Lu, Robin A., Yaffe, Micheal B., Ridinger, Maya, Damia, Giovanna, Guffanti, Federica

“…Occurrence of resistance to olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) approved in ovarian carcinoma, has already been shown in clinical…”
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Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins by Lu, Robin A, Zeki, Amir A, Ram-Mohan, Sumati, Nguyen, Nhan, Bai, Yan, Chmiel, Kenneth, Pecic, Stevan, Ai, Xingbin, Krishnan, Ramaswamy, Ghosh, Chandra C

“…Despite maximal use of currently available therapies, a significant number of asthma patients continue to experience severe, and sometimes life-threatening…”
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Abstract A035: Genome-wide CRISPRi screening reveals determinants of platinum sensitivity and resistance in high-grade serous ovarian cancer by Kong, Yi Wen, Handly, Erika D., Lu, Robin A., Bird, Molly A., Schilling, Hannah-Lou, Yaffe, Samkyu P., Yaffe, Michael B., Koch, David H.

“…Abstract Platinum-based chemotherapeutic drugs induce intra- and interstrand crosslinks between purine residues, resulting in DNA damage and tumor cell death…”
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