Search Results - "Lu, PeiWen"

De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report by Gandhi, Shiv, Klein, Jonathan, Robertson, Alexander J., Peña-Hernández, Mario A., Lin, Michelle J., Roychoudhury, Pavitra, Lu, Peiwen, Fournier, John, Ferguson, David, Mohamed Bakhash, Shah A. K., Catherine Muenker, M., Srivathsan, Ariktha, Wunder, Elsio A., Kerantzas, Nicholas, Wang, Wenshuai, Lindenbach, Brett, Pyle, Anna, Wilen, Craig B., Ogbuagu, Onyema, Greninger, Alexander L., Iwasaki, Akiko, Schulz, Wade L., Ko, Albert I.

“…SARS-CoV-2 remdesivir resistance mutations have been generated in vitro but have not been reported in patients receiving treatment with the antiviral agent. We…”
Get full text

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling by Israelow, Benjamin, Song, Eric, Mao, Tianyang, Lu, Peiwen, Meir, Amit, Liu, Feimei, Alfajaro, Mia Madel, Wei, Jin, Dong, Huiping, Homer, Robert J, Ring, Aaron, Wilen, Craig B, Iwasaki, Akiko

“…Severe acute respiratory syndrome-coronavirus 2 (SARS-Cov-2) has caused over 13,000,000 cases of coronavirus disease (COVID-19) with a significant fatality…”
Get full text

Neuroinvasion of SARS-CoV-2 in human and mouse brain by Song, Eric, Zhang, Ce, Israelow, Benjamin, Lu-Culligan, Alice, Prado, Alba Vieites, Skriabine, Sophie, Lu, Peiwen, Weizman, Orr-El, Liu, Feimei, Dai, Yile, Szigeti-Buck, Klara, Yasumoto, Yuki, Wang, Guilin, Castaldi, Christopher, Heltke, Jaime, Ng, Evelyn, Wheeler, John, Alfajaro, Mia Madel, Levavasseur, Etienne, Fontes, Benjamin, Ravindra, Neal G, Van Dijk, David, Mane, Shrikant, Gunel, Murat, Ring, Aaron, Kazmi, Syed A Jaffar, Zhang, Kai, Wilen, Craig B, Horvath, Tamas L, Plu, Isabelle, Haik, Stephane, Thomas, Jean-Leon, Louvi, Angeliki, Farhadian, Shelli F, Huttner, Anita, Seilhean, Danielle, Renier, Nicolas, Bilguvar, Kaya, Iwasaki, Akiko

“…Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects multiple organ systems including the central nervous system (CNS)…”
Get full text

Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2 by Wyllie, Anne L, Fournier, John, Casanovas-Massana, Arnau, Campbell, Melissa, Tokuyama, Maria, Vijayakumar, Pavithra, Warren, Joshua L, Geng, Bertie, Muenker, M. Catherine, Moore, Adam J, Vogels, Chantal B.F, Petrone, Mary E, Ott, Isabel M, Lu, Peiwen, Venkataraman, Arvind, Lu-Culligan, Alice, Klein, Jonathan, Earnest, Rebecca, Simonov, Michael, Datta, Rupak, Handoko, Ryan, Naushad, Nida, Sewanan, Lorenzo R, Valdez, Jordan, White, Elizabeth B, Lapidus, Sarah, Kalinich, Chaney C, Jiang, Xiaodong, Kim, Daniel J, Kudo, Eriko, Linehan, Melissa, Mao, Tianyang, Moriyama, Miyu, Oh, Ji E, Park, Annsea, Silva, Julio, Song, Eric, Takahashi, Takehiro, Taura, Manabu, Weizman, Orr-El, Wong, Patrick, Yang, Yexin, Bermejo, Santos, Odio, Camila D, Omer, Saad B, Dela Cruz, Charles S, Farhadian, Shelli, Martinello, Richard A, Iwasaki, Akiko, Grubaugh, Nathan D, Ko, Albert I

“…In this letter, the investigators report that saliva specimens and nasopharyngeal swab specimens had similar sensitivity in the detection of SARS-CoV-2 RNA in…”
Get full text

Migrant memory B cells secrete luminal antibody in the vagina by Oh, Ji Eun, Iijima, Norifumi, Song, Eric, Lu, Peiwen, Klein, Jonathan, Jiang, Ruoyi, Kleinstein, Steven H., Iwasaki, Akiko

“…Antibodies secreted into mucosal barriers serve to protect the host from a variety of pathogens, and are the basis for successful vaccines 1 . In type I mucosa…”
Get full text

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets by Vogels, Chantal B. F., Brito, Anderson F., Wyllie, Anne L., Fauver, Joseph R., Ott, Isabel M., Kalinich, Chaney C., Petrone, Mary E., Casanovas-Massana, Arnau, Catherine Muenker, M., Moore, Adam J., Klein, Jonathan, Lu, Peiwen, Lu-Culligan, Alice, Jiang, Xiaodong, Kim, Daniel J., Kudo, Eriko, Mao, Tianyang, Moriyama, Miyu, Oh, Ji Eun, Park, Annsea, Silva, Julio, Song, Eric, Takahashi, Takehiro, Taura, Manabu, Tokuyama, Maria, Venkataraman, Arvind, Weizman, Orr-El, Wong, Patrick, Yang, Yexin, Cheemarla, Nagarjuna R., White, Elizabeth B., Lapidus, Sarah, Earnest, Rebecca, Geng, Bertie, Vijayakumar, Pavithra, Odio, Camila, Fournier, John, Bermejo, Santos, Farhadian, Shelli, Dela Cruz, Charles S., Iwasaki, Akiko, Ko, Albert I., Landry, Marie L., Foxman, Ellen F., Grubaugh, Nathan D.

“…The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exemplifies the critical need for accurate and rapid diagnostic assays to…”
Get full text

CD163-Mediated Small-Vessel Injury in Alzheimer's Disease: An Exploration from Neuroimaging to Transcriptomics by Chen, Yuewei, Lu, Peiwen, Wu, Shengju, Yang, Jie, Liu, Wanwan, Zhang, Zhijun, Xu, Qun

“…Patients with Alzheimer's disease (AD) often present with imaging features indicative of small-vessel injury, among which, white-matter hyperintensities (WMHs)…”
Get full text

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation by Kang, Seung Goo, Liu, Wen-Hsien, Lu, Peiwen, Jin, Hyun Yong, Lim, Hyung W, Shepherd, Jovan, Fremgen, Daniel, Verdin, Eric, Oldstone, Michael B A, Qi, Hai, Teijaro, John R, Xiao, Changchun

“…The robust generation of high-affinity antibodies by germinal center B cells requires help provided by T FH cells. Ansel and Xiao and their colleagues show…”
Get full text

Detection of SARS-CoV-2 RNA by multiplex RT-qPCR by Kudo, Eriko, Israelow, Benjamin, Vogels, Chantal B F, Lu, Peiwen, Wyllie, Anne L, Tokuyama, Maria, Venkataraman, Arvind, Brackney, Doug E, Ott, Isabel M, Petrone, Mary E, Earnest, Rebecca, Lapidus, Sarah, Muenker, M Catherine, Moore, Adam J, Casanovas-Massana, Arnau, Omer, Saad B, Dela Cruz, Charles S, Farhadian, Shelli F, Ko, Albert I, Grubaugh, Nathan D, Iwasaki, Akiko

“…The current quantitative reverse transcription PCR (RT-qPCR) assay recommended for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in the…”
Get full text

Characterization of white matter over 1–2 years in small vessel disease using MR-based quantitative susceptibility mapping and free-water mapping by Sun, Yawen, Hu, Ying, Qiu, Yage, Zhang, Yuyao, Jiang, Changhao, Lu, Peiwen, Xu, Qun, Shi, Yuting, Wei, Hongjiang, Zhou, Yan

“…Purpose The aim of this study was to investigate alterations in white matter lesions (WMLs) and normal-appearing white matter (NAWM) with small vessel disease…”
Get full text

The Contribution of White Matter Diffusion and Cortical Perfusion Pathology to Vascular Cognitive Impairment: A Multimode Imaging-Based Machine Learning Study by Wang, Yao, Lu, Peiwen, Zhan, Yafeng, Wu, Xiaowei, Qiu, Yage, Wang, Zheng, Xu, Qun, Zhou, Yan

“…Widespread impairments in white matter and cerebrovascular integrity have been consistently implicated in the pathophysiology of patients with small vessel…”
Get full text

Multi-Dimensional Diffusion Tensor Imaging Biomarkers for Cognitive Decline From the Preclinical Stage: A Study of Post-stroke Small Vessel Disease by Du, Jing, Zhu, Hong, Yu, Ling, Lu, Peiwen, Qiu, Yage, Zhou, Yan, Cao, Wenwei, Lu, Dong, Zhao, Wei, Yang, Jie, Sun, Junfeng, Xu, Qun

“…Objectives: We aim to investigate whether multi-dimensional diffusion tensor imaging (DTI) measures can sensitively identify different cognitive status of…”
Get full text

Would science serve decision-making to adapt the impact of climate change? Introduction to Climate Change Adaptation - scientific evidence, assessment framework and decision-making by Liu, Gin-Rong, Lu, Peiwen

“…We live in challenging times with a heightened sense of uncertainty and unpredictability. Climate change, with its impact on disruptive events as well as…”
Get full text

Successful application of prime and pull strategy for a therapeutic HSV vaccine by Bernstein, David I., Cardin, Rhonda D., Bravo, Fernando J., Awasthi, Sita, Lu, Peiwen, Pullum, Derek A., Dixon, David A., Iwasaki, Akiko, Friedman, Harvey M.

“…One promising approach for a herpes simplex virus vaccine uses a vaccine to prime and a chemoattractant to pull immune cells into the genital tract. We…”
Get full text

Endogenous Retroviruses Provide Protection Against Vaginal HSV-2 Disease by Jayewickreme, Radeesha, Mao, Tianyang, Philbrick, William, Kong, Yong, Treger, Rebecca S, Lu, Peiwen, Rakib, Tasfia, Dong, Huiping, Dang-Lawson, May, Guild, W Austin, Lau, Tatiana J, Iwasaki, Akiko, Tokuyama, Maria

“…Endogenous retroviruses (ERVs) are genomic sequences that originated from retroviruses and are present in most eukaryotic genomes. Both beneficial and…”
Get full text

Examining resilience in local adaptation policies - pilot studies in Taipei and Tainan, Taiwan by Lu, Peiwen, Huang, Ellie Yu-Hui, Liang, Shu-Yun, Liu, Gin-Rong

“…Resilience has gained considerable attention over recent years in both theories and decision-making practices. In Taiwan, the term resilience is generally…”
Get full text

Understanding the notion of resilience in spatial planning: A case study of Rotterdam, The Netherlands by Lu, Peiwen, Stead, Dominic

“…•Urban resilience is a broad concept that is sometimes blurred and abstract.•Urban resilience addresses adaptation as well as mitigation.•Urban resilience is…”
Get full text

Participation beyond a form of urban tactics - Examining contemporary urban spatial development strategies through Taipei PCC's street play activities by Lu, Peiwen, Wang, Chunhung

“…This article investigates the influence of tactical urbanism on planning for everyday living, employing ‘Parks for Children by Children (PCC)’s street play…”
Get full text

From science to practices – lessons learned from the TaiCCAT research programme by Lu, Peiwen, Shen, Yang Ting, Liu, Gin-Rong, Lin, Tang-Huang

Get full text

Identification of a new isoform of the murine Sh2d1a gene and its functional implications by Wu, LongYan, Lu, PeiWen, Ma, WeiWei, Chu, CoCo, Xu, HePing, Qi, Hai

“…Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is a Src homology (SH) domain 2-containing intracellular adaptor protein that is…”
Get full text